Ce glossaire actualisé sur le paludisme vise à améliorer la communication et la compréhension mutuelle au sein de la communauté scientifique, ainsi qu'avec les organismes de financement, les responsables de la santé publique chargés des programmes de lutte contre le paludisme et les décideur...s des pays où le paludisme est endémique.
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Antimalarial drug resistance has emerged as a threat to global malaria control efforts, particularly in the Greater Mekong subregion. Drawing on data collected through more than 1000 therapeutic efficacy studies as well as molecular marker studies of Plasmodium falciparum drug resistance, the Report... on antimalarial drug efficacy, resistance and response: 10 years of surveillance (2010–2019) presents a decade’s worth of data on drug efficacy and surveillance, as well as recommendations to monitor and protect the efficacy of malaria treatment in the decades to come.
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procédures : guide méthodologique
La page du PNLP Côte d’Ivoire présente une synthèse du paludisme, une maladie parasitaire grave transmise par les moustiques Anopheles. Elle décrit les espèces de Plasmodium, les symptômes principaux, le cycle de transmission et souligne l’importance de la prévention et du traitement rapi...de pour réduire les décès liés à la maladie.
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Le plan stratégique de la RBM Partnership to End Malaria pour 2021-2025 présente les priorités stratégiques du partenariat mondial visant à éliminer le paludisme. Le document se concentre sur trois objectifs stratégiques principaux : optimiser les programmes régionaux et nationaux, maximiser... le financement et faciliter le déploiement de nouveaux produits et stratégies. Le plan met l'accent sur la collaboration multisectorielle, en exploitant les partenariats au niveau mondial, régional et national pour lutter efficacement contre le paludisme. Il souligne également l'importance du partage de données, du plaidoyer et de la communication pour garantir que le paludisme reste une priorité en matière de santé. Le document met aussi en lumière les défis posés par la pandémie de COVID-19 et la nécessité de maintenir l'élan dans la lutte contre le paludisme.
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Lancet 2020 ; 396 : 1829-40
Pour l'achat de tests de diagnostic rapide du paludisme (TDR), plusieurs critères sont recommandés pour garantir la qualité et l'efficacité des tests. Ces critères se basent notamment sur la performance des tests, leur stabilité, leur facilité d'utilisation, leur coût et leur conformité aux... standards de l'Organisation Mondiale de la Santé (OMS)
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Ce document intitulé « Diagnostic, traitement et prévention du paludisme : directive pour le personnel médical », publié par les Nations Unies en avril 2019, fournit des recommandations pratiques pour le personnel médical travaillant dans des zones à risque de paludisme. Il décrit les signe...s cliniques du paludisme, les méthodes de diagnostic (tests rapides et microscopie), et détaille les traitements recommandés selon l’espèce de Plasmodium et la gravité de l’infection. Il aborde également les cas particuliers, comme les femmes enceintes et les enfants, ainsi que la prévention à travers les moustiquaires, les répulsifs et la chimioprophylaxie. Enfin, il donne des consignes pour les voyageurs de l’ONU, y compris la conduite à tenir en cas de fièvre après un retour de zone endémique.
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How can we eradicate malaria? Explore cutting-edge science and technology, and examine policies needed, to control and eliminate malaria.
The reports bring together the latest findings and conclusions about the state of resistance to artemisinins and artemisinin-based combination therapy (ACT), summarize WHO’s current policy and treatment recommendations, and highlight areas of concern.
This WHO information note provides an updated list of recommended criteria for selecting RDTs for malaria, and highlights the performance of RDTs evaluated by the WHO malaria RDT product testing programme. It also provides an overview of additional considerations in the procurement of rapid tests.
(African Development Bank policy research document 1)
The report examines financing in the battle against malaria, focusing on the role of foreign aid. It analyzes whether or not a disease such as malaria can be controlled or eliminated in Africa without health aid. It also presents a theoretic...al model of the economics of malaria and shows how health aid can help avoid the “disease trap.” While calling for increased funding from international sources to fight malaria, it also recommends that African countries step up their own efforts, including on domestic resource mobilization. In 2016, governments of endemic countries contributed 31% of the estimated total of US $ 2.7 billion.
Between 2000 and 2014, malaria control efforts were scaled up and worldwide deaths were cut in half. But declining health aid and deprioritized vertical aid (as for malaria), despite its potentially great efficiency, have led to rising numbers of cases. In 2016, 216 million cases of malaria were reported, up from 211 million in 2015. Africa was home to 90% of all malaria cases and 91% of malaria deaths in 2016. Progress appears to have stalled in the global fight against the disease.
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This report, published in conjunction with a summary overview of results of rounds 1–8, is the eighth and final report in a series of laboratory-based evaluations of rapid diagnostic tests (RDTs) for malaria. It provides a comparative measure of their performance in a standardized way to distingui...sh between well and poorly performing tests.
These results constitute the laboratory evaluation component of the WHO prequalification process for malaria RDTs and inform the current WHO procurement recommendations. In round 8, 35 RDTs from 17 manufacturers were assessed. For the first time the evaluation included an assessment of product performance against a panel of P. falciparum parasites with pfhrp2/3 gene deletions and therefore not expressing HRP2.
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Le panorama du paludisme a profondement changé durant la dernière décénnie. Les financements ont augmenté, les outils permettant de sauver des vies ont été mis en œuvre à plus grande échelle, la charge du paludisme a diminué et un nombre grandissant de pays envisagent son élimination.
C...e cadre actualisé fait le point sur les outils, les activités et les stratégies nécessaires pour atteindre l'élimination du paludisme et empêcher la reprise de la transmission dans les pays, quelle que soit l'étape à laquelle ils se trouvent sur la route menant à l'élimination ou l’intensité de la transmission. Le cadre est destiné à servir de référence pour élaborer des plans stratégiques d’élimination du paludisme au niveau national et doit être adapté aux contextes locaux.
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The document provides an overview of malaria in the Americas, describing its transmission, symptoms, vulnerable populations, and regional trends, while highlighting prevention strategies and the efforts of PAHO/WHO and member states to eliminate the disease by 2020.
The document WHA70.16, adopted during the 70th World Health Assembly, outlines a global strategy for an integrated response to vector-borne diseases. It emphasizes the urgent need to strengthen national and global capacities for vector control amid rising threats such as insecticide resistance, clim...ate change, and the spread of vectors like mosquitoes. Member States are urged to align their national strategies with WHO’s integrated approach, improve surveillance, promote research, and ensure cross-sector and cross-border collaboration. The WHO Director-General is requested to provide technical support, promote innovation, and monitor progress, with regular updates to future World Health Assemblies.
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Le Cadre stratégique de la communication pour le changement social et comportemental concernant le paludisme 2018–2030, élaboré par le Partenariat RBM, propose une approche coordonnée pour renforcer la communication dans la lutte contre le paludisme. Il vise à influencer positivement les comp...ortements individuels, communautaires et institutionnels à travers des stratégies adaptées aux contextes locaux. Le document met l’accent sur la participation communautaire, l’utilisation des données pour orienter les interventions, et la collaboration entre secteurs afin de soutenir les efforts mondiaux d’élimination du paludisme d’ici 2030.
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The document titled "Checklist for Assessing Management of Severe Malaria" is part of the MalariaCare Toolkit. It provides a structured tool for supervisors conducting outreach training and supportive supervision (OTSS) visits in healthcare facilities. The checklist is designed to evaluate and guide... the clinical management of severe malaria cases, including diagnostics, treatment planning, complication management, patient monitoring, and the administration of injectable artesunate. It also includes sections for direct observation of clinical procedures and supervisor feedback to help improve healthcare worker performance and adherence to national treatment guidelines.
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2nd edition. WHO's recommendation has not changed: the standard WHO susceptibility tests should remain a primary method by which resistance is detected. However, it was considered necessary to update the existing resistance-monitoring procedures to also highlight the need for operationally meaningfu...l data.
Two new assays were included in this expanded version: an intensity assay and a synergist assay.
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This toolkit for integrated vector management (IVM) is designed to help national and regional programme managers coordinate across sectors to design and run large IVM programmes.
The toolkit provides the technical detail required to plan, implement, monitor and evaluate an IVM approach. IVM can... be used when the aim is to control or eliminate vector-borne diseases and can also contribute to insecticide resistance management. This toolkit provides information on where vector-borne diseases are endemic and what interventions should be used, presenting case studies on IVM as well as relevant guidance documents for reference.
The diseases that are the focus of this toolkit are malaria, lymphatic filariasis, dengue, leishmaniasis, onchocerciasis, human African trypanosomiasis and schistosomiasis. It also includes information on other viral diseases (Rift Valley fever, West Nile fever, Chikungunya, yellow fever) and trachoma. If other vector-borne diseases appear in a country or area, vector control with an IVM approach should be adopted, as per national priorities.
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