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Standard Treatment Guidelines. Nigeria

Federal Ministry of Health Nigeria , World Health Organisation (WHO) (2008) C_WHO

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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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WHO manual for HIV drug resistance testing using dried blood spot specimens

World Health Organization WHO (2020) C_WHO

HIV-1 drug resistance (HIVDR) genotyping is an essential component of the WHO global HIVDR surveillance strategy. Plasma “gold standard” specimen type for HIVDR genotyping, but its use may not be feasible in rural, remote areas in low- and middle-income countries, since preparing and storing it ... more

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Clinic Supervisor Manual

Management Sciences for Health; USAID (2006) C1

This Clinic Supervisor’s Manual is helpful for focusing managers on the key elements of integrated primary health care as they simultaneously integrate new interventions for HIV/AIDS, tuberculosis, and malaria. This tool contains 12 sections. Section 1 explains how to use the manual. Section 2 hel... more

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Botswana: Guidelines on Good Manufacturing Practices

Ministry of Health, Gabarone, Botswana (2009) C2

Drug Advisory Board

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Community Health Extension Workers Strategy in Uganda (2015/16- 2019/20)

Ministry of Health, Republic of Uganda (2016) C1

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Diagnostics, therapeutics, vaccine readiness, and other health products for COVID-19
recommended

World Health Organization WHO (2021) C_WHO

Interim Guidance, 12 July 2021; This tool was developed to assess present and surge capacities for the treatment of COVID-19 in health facilities. It allows health facilities to assess the availability and status of stockout of critical COVID-19 medicines, equipment and supplies on site and to ident... more

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Report of the United Nations High Commissioner for Human Rights on the situation of Human rights in the Bolivarian Republic of Venezuela (A/HRC/41/18)

UN Human Rights Council (2019) C1

(Advance unedited version)

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Ukraine HIV Program Efficiency Study: Can Ukraine improve value for money in HIV service delivery?

International Bank for Reconstruction and Development The World Bank (2019) C2

Accessed: 04.10.2019 The data collection process was organized by UCDC Director, Natalia Nizova, and M&E Department Head, Igor Kuzin, and implemented by M&E specialists from oblast AIDS Centers: Zhanna Antonenko, Oksana Gorbachuk, Volodymyr Zahorovskyi (Kiev City); Anna Lopatenko, Irina Kozina, I... more

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Guidelines for the Development of Pharmaceutical Services in Primary Health Care

Pan American Health Organization (PAHO) (2011) C_WHO

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Uganda: Food Security and Nutrition Assessment Karamoja Region, June 2015

World Food Programme, UNICEF (2015)

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The World Climate and Security Report 2021

Brock, S.; Barrett, O.L.; Birkman, L.; et al. International Military Council on Climate and Security (2021) CC

The World Climate and Security Report (WCSR) 2021 from the Expert Group of the International Military Council on Climate and Security is a global assessment of the security dimensions of a changing climate and effective means to address them. It is intended to inform timely climate and security po... more

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Strategies to prevent diversion of opioid substitution treatment medications

European Monitoring Centre for Drugs and Drug Addiction (2016) C2

Perspectives on Drugs

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Severe acute respiratory infections treatment centre: practical manual to set up and manage a SARI treatment centre ( Arabic Version)

World Health Organization WHO (2020) C_WHO

آذار / مارس 2020مركز معالجة حالات العدوى التنفسیة الحادة الوخیمةدلیل عملي لإنشاء وإدارة مركز لمعالجة حالات العدوى التنفسیة الحادة الوخیمة وقسم لتحري المصابین بھذه ا�... more

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Public Health Emergency Response Guide for State, Local, and Tribal Public Health Directors - Version 2.0

Centers for Disease Control and Prevention (CDC) (2011) C_CDC

This guide is intended to assist state, local, and tribal public health professionals in the initiation of response activities during the first 24 hours of an emergency or disaster. It should be used in conjunction with existin... more

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National Community Health Worker Strategy in Zambia

Ministry of Health, Zambia (2010) C1

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Sanitation inspections User guide

World Health Organization WHO (2024) C_WHO

Safe sanitation is essential for health, from preventing infections to improving and maintaining mental and social well-being. Lack of adequate sanitation contributes to diarrhoeal diseases, parasitic infections, and undernutrition, as well as posing significant risks and causing anxiety, especial... more

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Human Health: Impacts,Adaptation, and Co-Benefits

Smith, K.R., A. Woodward, D. Campbell-Lendrum, D.D. , et al. (2014) CC

In Climate Change 2014: Impacts, Adaptation, and Vulnerability. Part A: Global and Sectoral Aspects. Contribution of Working Group II to the Fifth Assessment Report of the Intergovernmental Panel on Climate Change

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Health Sector Transformation in Quality: First Edition 2016

Federal Democratic Republic of Ethiopia -Ministry of Health (2016) C1

A guide to support implementation of health service Quality Improvement activities in Ethiopian health facilities

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Sierra Leone: Facility Improvement Team (FIT) Assessment Report, November 2015

Ministry of Health and Sanitation Sierra Leone, Reproductive and Child Health Directorate (2015) C1

Diagnostics, therapeutics, vaccine readiness, and other health products for COVID-19 recommended

Diagnostics, therapeutics, vaccine readiness, and other health products for COVID-19
recommended