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Clinical guidelines - Diagnosis and treatment manual Chapter 6: Parasitic diseases

MSF, Dubois, G.; Vasseur-Binachon, B.; Yoshimoto, C. Médecins Sans Frontières (2022) CC

Chapter 6 contents Malaria Human African trypanosomiasis (sleeping sickness) American trypanosomiasis (Chagas disease) Leishmaniases Intestinal protozoan infections (parasitic diarrhoea) Flukes Schistosomiases Cestodes Nematode infections Filariasis ... more

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Trainer Manual: Managing FGS in Primary Health Care

Countdown Calling Time on Neglected Tropical Diseases Sightsavers (2021) CC

This trainer toolkit is a guide for Neglected Tropical Diseases (NTD) program implementers in Nigeria to train primary health care health workers to diagnose and provide care for women and girls with symptoms of female genital schistosomiasis (FGS). It has been developed based on a pilot study in ... more

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Supply chain management of NTD health products for NTD programmes

Open WHO; World Health Organization WHO (2022) C_WHO

A key component of achieving control and elimination of neglected tropical diseases (NTDs) is effective supply chain management of preventive chemotherapy drugs for Mass Drug Administration (MDA) for trachoma, river blindness, lymphatic filariasis, soil-transmitted helminthiasis and schistosomiasis.... more

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Für eine gesunde Zukunft: Gemeinsam gegen übertragbare tropische Armutskrankheiten, Mangel- und Unterernährung

Global Network for Neglected Tropical Diseases (2015) C2

Dieses Kurzdossier konzentriert sich besonders auf den Zusammenhang zwischen zwei übertragbaren tropischen Armutserkrankungen – dem Wurmbefall des Darms durch Geohelminthen wie Spul-, Peitschen- und Hakenwürmer sowie der Schistosomiasis (Bilharziose). Es zeigt Möglichkeiten zu deren Bekämpf... more

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Water sanitation and hygiene for accelerating and sustaining progress on neglected tropical diseases: A global strategy 2015-2020

World Health Organization (WHO) (2015) C_WHO

Water, sanitation and hygiene (WASH) are critical in the prevention and care for all of the 17 neglected tropical diseases (NTDs) scheduled for intensified control or elimination by 2020.
Provision of safe water, sanitation and hygiene is one of the five key interventions within the global NTD ... more

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Current epidemiological evidence for predisposition to high or low intensity human helminth infection: a systematic review

Wright J.E., Werkman M., Dunn J.C. et al Parasites and Vectors (2018) C2

Background: The human helminth infections include ascariasis, trichuriasis, hookworm infections, schistosomiasis, lymphatic filariasis (LF) and onchocerciasis. It is estimated that almost 2 billion people worldwide are infected with helminths. Whilst the WHO treatment guidelines for helminth infecti...ons are mostly aimed at controlling morbidity, there has been a recent shift with some countries moving towards goals of disease elimination through mass drug administration, especially for LF and onchocerciasis. However, as prevalence is driven lower, treating entire populations may no longer be the most efficient or cost-effective strategy. Instead, it may be beneficial to identify individuals or demographic groups who are persistently infected, often termed as being “predisposed” to infection, and target treatment at them. Methods: The authors searched Embase, MEDLINE, Global Health, and Web of Science for all English language, humanbased papers investigating predisposition to helminth infections published up to October 31st, 2017. The varying definitions used to describe predisposition, and the statistical tests used to determine its presence, are summarised. Evidence for predisposition is presented, stratified by helminth species, and risk factors for predisposition to infection are identified and discussed. Results: In total, 43 papers were identified, summarising results from 34 different studies in 23 countries. Consistent evidence of predisposition to infection with certain species of human helminth was identified. Children were regularly found to experience greater predisposition to Ascaris lumbricoides, Schistosoma mansoni and S. haematobium than adults. Females were found to be more predisposed to A. lumbricoides infection than were males. Household clustering of infection was identified for A. lumbricoides, T. trichiura and S. japonicum. Ascaris lumbricoides and T. trichiura also showed evidence of familial predisposition. Whilst strong evidence for predisposition to hookworm infection was identified, findings with regards to which groups were affected were considerably more varied than for other helminth species. Conclusion: This review has found consistent evidence of predisposition to heavy (and light) infection for certain human helminth species. However, further research is needed to identify reasons for the reported differences between demographic groups. Molecular epidemiological methods associated with whole genome sequencing to determine ‘who infects whom’ may shed more light on the factors generating predisposition. more

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Standard operating procedures for supply chain management of health products for neglected tropical diseases amenable to preventive chemotherapy
recommended

World Health Organization WHO (2022) C_WHO

Tis first edition describes the standard operating procedures for health products for NTDs amenable to preventive chemotherapy and the medicines donated to treat them. These include albendazole for lymphatic filariasis and soil-transmitted helminthiases; azithromycin for trachoma and yaws; diethylca... more

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ANNUAL REPORT NTDs 2023

World Health Organization WHO (2024) C_WHO

This report represents the WHO-supported NTDs program activities and key performances in 2023. It is categorized into three sections: The first section states on the disease targeted for eradication (Guinea worm disease); the second section is on the Preventive Chemotherapy (PC)-NTDs (Trachoma, ... more

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Burden of disease from inadequate water, sanitation and hygiene for selected adverse health outcomes: An updated analysis with a focus on low- and middle-income countries

Prüss-Ustün A., Wolf J., Bartram J., et al. (2019) CC

Int J Hyg Environ Health. 2019 Jun; 222(5): 765–777. doi: 10.1016/j.ijheh.2019.05.004; To develop updated estimates in response to new exposure and exposure-response data of the burden of diarrhoea, respiratory infections, malnutrition, schistosomiasis, malaria, soil-transmitted helminth infec... more

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Boîte à outils pour une gestion vectorielle intégrée en Afrique subsaharienne

Organisation mondiale de la Santé (OMS) (2016) C_WHO

This toolkit for integrated vector management (IVM) is designed to help national and regional programme managers coordinate across sectors to design and run large IVM programmes. The toolkit provides the technical detail required to plan, implement, monitor and evaluate an IVM approach. IVM can be ... more

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A toolkit for integrated vector management in sub-Saharan Africa

World Health Organization (WHO) (2016) C_WHO

This toolkit for integrated vector management (IVM) is designed to help national and regional programme managers coordinate across sectors to design and run large IVM programmes.
The toolkit provides the technical detail required to plan, implement, monitor and evaluate an IVM approach. IVM can... more

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Water, Sanitation and Hygiene: Foundations of Development

Brocklehurst C. (2011) CC

The disease burden caused by poor water, sanitation and hygiene is significant. For instance, soil transmitted helminthes (hookworm, roundworm, ringworm) infest approximately two billion people. Shistosomiasis infects and debilitates 200 million people. Trachoma, a disease related to poor sanitation... more

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Baseline Mapping of Neglected Tropical Diseases in Africa: The Accelerated WHO/AFRO Mapping Project

Rebollo M.P., Onyeze A.N., Tiendrebeogo A. et al The American Society of Tropical Medicine and Hygiene (2021) C2

ajtmh.20-1538 Volume 104, 6. Mapping is a prerequisite for effective implementation of interventions against neglected tropical diseases (NTDs). Before the accelerated World Health Organization (WHO)/Regional Office for Africa (AFRO) NTD Mapping Project was initiated in 2014, mapping efforts in man... more

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داء البلهارسيات

World Health Organization WHO (2023) C_WHO

داء البلهارسيات هو مرض طفيلي حاد ومزمن تسبّبه الديدان المثقوبة الدموية (المثقوبات) من جنس البلهارسية. وتشير التقديرات إلى أن 251.4 مليون شخص على الأقل كانوا بحاجة إلى �... more