The Committee examined the clinical development of Ebola virus vaccines and conducted an inventory of available data on their safety. It also reviewed 3 generic issues: updating a global strategy on vaccine safety, use of a network of distributed data ... to monitor the safety of vaccines and case studies of communication about the safety of human papillomavirus (HPV) vaccines.
Weekly epidemiological record/Relevé épidémiologique hebdomadaire 12 JULY 2019, 94th YEAR / 12 JUILLET 2019, 94e ANNÉENo 28, 2019, 94, 309–316
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Clinical management standard operating procedures.
Ebola virus disease (EVD) is a life-threatening multisystem illness associated with fever and gastrointestinal (GI) symptoms that frequently leads to hypovolaemia, metabolic acidosis, hypoglycaemia, and multi-organ failure. The prolonged 2013–201...6 EVD outbreak in West Africa allowed for an evolution of care such that by outbreak end many patients received individualized and optimized supportive care (oSoC), including volume resuscitation, symptom control, laboratory and bedside monitoring of glucose, electrolyte levels and organ dysfunction, as well as rapid detection and treatment of co-infections, potentially contributing to the downward trend in the case fatality rate (CFR).
This guidance should serve as a foundation for oSoC that should be followed to ensure both the best possible chance for survival and allow for reliable comparison of investigational therapeutic interventions as part of a randomized controlled trial. This guideline provides recommendations for the management of adults and children.
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The course consist of one module, which provides information on the history of the Ebola virus, diagnosis and treatment. In addition the module covers topics such as transmission pathways and vaccines.
All healthcare workers have free online access to this course.
The module is written to unders...tand more about the Ebola virus: How it spreads, how it can be controlled, the clinical symptoms and current and potential treatment.
Ebola[e]Education is a free available course. Register to gain access to the free courses.
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The GO training package was developed by the World Health Organization for use by staff, consultants and partners who are part of the emergency response, so that they can work safely as part of the teams working to bring the outbreak under control.
Training outline:
Module 1: Pre-deployment tr...aining
Module 2: Introduction to Ebola
Module 3: Global Ebola response
Module 4: Pillars of the global Ebola response
Module 5: Working with WHO
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A new FMP was opened in Lutaya (Yei County), bringing the total number of EVD-related FMPs within South Sudan to 14. Six additional FMPs are operated in cooperation with DTM Uganda on the Ugandan side of the border due to access issues on the South Sudanese side.
A field mission was carried ou...t in Yambio County to scope potential new FMP locations, provide the enumerators in Gangura with refresher training and improve arrangements for data upload.
Installation of incinerators and waste pits for medical waste management is ongoing at Morobo and Panyume Primary Health Care Centres (PHCC).
Two new POE screening sites established in Lasu and Birigo were officially opened and have started screening activities on the reporting period, making the total active IOM-supported PoE screening sites at 13
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En réponse à la réduction de l’espace humanitaire au Nord Kivu, en République démocratique du Congo (RDC), ce rapport met en lumière les pratiques des ONG opérant dans la zone, en termes de négociation d’accès. Il explore la manière dont les communautés et les Acteurs Armés Non Etati...ques (AANE) perçoivent les différents intervenants humanitaires actifs dans la région et comment les ONG négocient leur accès. Sur cette base, le rapport liste des recommandations visant à améliorer l’accès humanitaire au Nord Kivu, permettant ainsi une meilleure réponse aux besoins des populations civiles.
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An example of integration of research into epidemic response.
Cependant depuis le début du mois de décembre, une augmentation importante de l’incidence des nouveaux cas est observée particulièrement le long du corridor vers le grand centre urbain de Butembo (zones de santé de Butembo et Katwa) et au-delà dans la zone de santé de Kayna située à envir...on 150 km de Goma. Par ailleurs, des foyers actifs ont émergé vers le nord notamment dans les zones de santé de Komanda et Oicha.
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This brief summarises key considerations about the social, political and economic context of Goma in relation to the outbreak of Ebola in the DRC as of March 2019. Goma is the administrative capital of North Kivu province and a major urban centre in the Great Lakes Region. The city is home to an est...imated 1.5 million people and serves as an important economic and transportation hub that links eastern Congo to the broader East African sub-region. The arrival of Ebola in Goma would substantially increase the at-risk population and heighten the potential for cross-border transmission to neighbouring countries, particularly Rwanda. This brief therefore focuses on local social and political structures that can be leveraged to promote preparedness and readiness actions.
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Risk of spill-over of EVD to Uganda has been categorised as very high. On 28 September 2018, WHO elevated the risk at the regional level which includes Uganda from ‘high’ to ‘very high’. Uganda has a very long and largely porous border with the DRC. High population movements across the borde...rs occur for various reason including for trade, social activities and services and asylum. There are cross-border markets in several border districts in Uganda and DRC that involve thousands of people crossing into and out of DRC and Uganda for trade purposes several days in a week.
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Risk communication is a core public health intervention in any disease outbreak and health emergency. It refers to the real-time exchange of information, advice and opinions between experts, officials and people who face a threat to their wellbeing, to enable informed decision-making and to adopt pr...otective behaviors.
Learning objective: By the end of this course, participants should be able to understand the core principles of risk communication and its application to disease outbreaks and health emergencies.
Course duration: This course consists of an introductory video lecture, presentation slides that can be downloaded and reviewed at your own pace, and instructions for simulation exercises. Course duration may vary. It will take most participants approximately 8 hours to thoroughly complete all components.
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This brief draws out some recommendations for Ebola response actors in North Kivu. It includes lessons learned primarily from (i) historical outbreaks in Congo; (ii) outbreaks in Uganda in 2000-01 and 2012; (iii) the 2014-2016 West African epidemic; (iv) the outbreak in Equateur Province in DRC (May...- July 2018), and (v) the ongoing outbreak in North Kivu and Ituri Provinces in DRC (August 2018 - ongoing). The full report can be accessed here: https://opendocs.ids.ac.uk/opendocs/handle/123456789/14160.
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La flambée de maladie à virus Ebola (MVE) se poursuit avec une intensité modérée. Katwa et Butembo demeurent les principales zones sanitaires inquiétantes, tandis que de petites grappes continuent d’apparaître dans diverses zones géographiquement dispersées. Au cours des 21 derniers jours... (6 - 26 février 2019), 77 nouveaux cas ont été notifiés dans 33 secteurs de neuf zones sanitaires (Figure 1) : Katwa (45), Butembo (19), Vuhovi (4), Kyondo (3), Kalunguta (2), Oicha (1), Beni (1), Mandima (1) et Rwampara (1).
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The World Health Organization (WHO) and the Uganda Red Cross Society today signed an agreement to strengthen the screening of travellers at 25 points of entry in eight districts on the border between Uganda and the Democratic Republic of the Congo (DRC).
The support will also go towards training 22...9 frontline health workers and volunteers on infection prevention and control.
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