Globalization and Health201612:63; DOI: 10.1186/s12992-016-0195-3
Pan African Medical Journal 2017;27:215. doi: 10.11604/pamj.2017.27.215.12994
Of the 50 antibiotics in the pipeline, 32 target WHO priority pathogens but the majority have only limited benefits when compared to existing antibiotics. Two of these are active against the multi-drug resistant Gram-negative bacteria, which are spreading rapidly and require urgent solutions.
Gr...am-negative bacteria, such as Klebsiella pneumoniae and Escherichia coli, can cause severe and often deadly infections that pose a particular threat for people with weak or not yet fully developed immune systems, including newborns, ageing populations, people undergoing surgery and cancer treatment.
The report highlights a worrying gap in activity against the highly resistant NDM-1 (New Delhi metallo-beta-lactamase 1), with only three antibiotics in the pipeline. NDM-1 makes bacteria resistant to a broad range of antibiotics, including those from the carbapenem family, which today are the last line of defence against antibiotic-resistant bacterial infections.
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The global tripartite self-assessment survey of country progress in addressing antimicrobial resistance (AMR) is a component of a broader approach for monitoring and evaluation of the global action plan on AMR. This report analyses the results of the second tripartite self-assessment survey. It has ...been developed and run by the three Tripartite organizations (Food and Agriculture Organization of the United Nations (FAO), World Organisation for Animal Health (OIE) and World Health Organization (WHO)) and reflects progress in the human, animal (terrestrial and aquatic), plant, food safety and environmental sectors. 154 countries out of 194 WHO Member States responded to this round of the self-assessment survey – a response rate of 79.4%.
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The ECDC, the EFSA and the EMA have for the first time jointly explored associations between consumption of antimicrobials in humans and food-producing animals, and antimicrobial resistance in bacteria from humans and food-producing animals, using 2011 and 2012 data currently available from their re...levant five EU monitoring networks. Combined data on antimicrobial consumption and corresponding resistance in animals and humans for EU MSs and reporting countries were analysed using logistic regression models for selected combinations of bacteria and antimicrobials. A summary indicator of the proportion of resistant bacteria in the main food-producing animal species was calculated for the analysis, as consumption data in food-producing animals were not available at the species level
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PERC produces regional and member state situation analyses, updated regularly.
PERC produces regional and member state situation analyses, updated regularly.
PERC produces regional and member state situation analyses, updated regularly.
PERC produces regional and member state situation analyses, updated regularly.
PERC produces regional and member state situation analyses, updated regularly.
PERC produces regional and member state situation analyses, updated regularly.
PERC produces regional and member state situation analyses, updated regularly.
PERC produces regional and member state situation analyses, updated regularly.
PERC produces regional and member state situation analyses, updated regularly.
PERC produces regional and member state situation analyses, updated regularly.
PERC produces regional and member state situation analyses, updated regularly.
PERC produces regional and member state situation analyses, updated regularly.
PERC produces regional and member state situation analyses, updated regularly.