There is an urgent need for safer, simpler, more efficacious and accessible treatment regimens for all forms of TB. The development of Target Product Profiles for TB treatment regimens (referred to as Target Regimen Profiles or TRPs) seeks to guide the drug development process towards important regi...men characteristics corresponding to the needs of end-users.
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Q10: For carers of people with dementia, does respite care when compared to care as usual, produce benefits/harm in the specified outcomes?
WHO working group on HIV incidence assays meeting report
10–11 December 2015
Glion, Switzerland
UNAIDS/WHO working group on global HIV/AIDS and STI surveillance
WHO/HIV/2017.03
Mpox continues to affect people around the world. A new framework released today by WHO will guide health authorities, communities and other stakeholders in preventing and controlling mpox outbreaks, eliminating human-to-human transmission of the disease, and reducing spillover of the virus from ani...mals to humans.
Mpox is a viral illness caused by the monkeypox virus (MPXV). It can cause a painful rash, enlarged lymph nodes and fever. Most people fully recover, but some get very sick. The virus transmits from person to person through close, including sexual, contact. It also has animal reservoirs in east, central and west Africa, where spillovers from animals to humans can occasionally occur, sparking further outbreaks.
There are two different clades of the virus: clade I and clade II. Clade I outbreaks are deadlier than clade II outbreaks.
A major emergence of mpox linked to clade II began in 2017, and since 2022, has spread to all regions of the world. Between July 2022 and May 2023, the outbreak was declared a Public Health Emergency of International Concern. While that outbreak has largely subsided, cases and deaths continue to be reported today, illustrating that low-level transmission continues around the world.
Currently, there is also a major outbreak of clade I virus in the Democratic Republic of the Congo (DRC), where cases have been on the rise for decades. Since the beginning of the year, over 6500 cases and 345 deaths have been reported in the DRC. Almost half of these are among children under the age of 15 years.
The Strategic framework for enhancing prevention and control of mpox (2024–2027) provides a roadmap for health authorities, communities, and stakeholders worldwide to control mpox outbreaks in every context, advance mpox research and access to countermeasures, and to minimize zoonotic transmission.
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What school closures under COVID-19 mean for children and young people in
crisis-affected contexts
On the global scale, the impacts of the current food system on the environment are severe. The agro-industrial revolution has made it possible to increase food production at a price.
Is the first appendix for the Psychological First Aid Field for Schools (PFA-S) Operations Guide. This appendix provides recommendations for school staff (including principals and administrators, teachers, health-related professionals, and support staff) on providing Psychological First Aid at a sch...ool.
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Цель данного доклада – стать ресурсом, позволяющим руководителям и другим заинтересованным сторонам рассматри-вать предупреждение самоубийств как императив. То...ько в этом случае страны смогут предпринять своевременные и эффективные меры на национальном уровне и, таким образом, избавить граждан, семьи, местные сообществаи общество в целом от бремени страданий, вызываемых самоубийствами и суицидальными попытками.
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Во многих странах суицид является одной из главных причин смерти среди детей и подростков. Одна из главных задач психиатрических служб – выяв-ление молодых людей ...з группы риска и предложение эффективных методов лечения. Данная глава содержит обзор суицидальности детей и подростков. Несуицидальные самоповреждения также будут рассмотрены, но основное внимание будет уделено суицидальным попыткам и завершенным суицидам. Обзор включает данные эпидемиологии, сведения о факторах риска и осо-бенностях этиологии, клинических проявлениях, диагностике, лечении и про-филактике. Поскольку акцент мы сделали на клинических проблемах, в этот обзор не вошли сведения о нейропсихобиологии суицидальности.
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Practical considerations
It provides more detailed and practical guidance for continuing services for each life stage across the life-course continuum. As such, both documents should be read and used together. The countries in South-East Asia and the Pacific regions would like to adapt the guidance... within the national and sub-national continuity plans, based on the local situation of COVID-19 transmission, containment response and health system capacity.
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As of 21 May 2020, 4.8 million confirmed cases of Coronavirus disease 2019 (COVID-19) have been reported globally. In South America, COVID-19 was first detected on 26 February 2020, when Brazil confirmed a case in São Paulo.