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Investment Case - At a glance - Eighth Replenishment 2025

The Global Fund (2025) CC
This is a moment of reckoning in the fight against HIV, tuberculosis (TB) and malaria. For our Eighth Replenishment, the Global Fund needs US$18 billion to save 23 million lives, cut the death rate from the three diseases by 64% and help build a healthier, safer and more equitable world.
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Global Fund Launches Private Sector Investment Opportunity Ahead of Critical Eighth Replenishment

The Global Fund The Global Fund (2025) CC
Private sector engagement opens pathways for a game-changing US$2 billion investment opportunity in the fight against HIV, tuberculosis and malaria.
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The cost of inaction on health equity and its social determinants

Yerramilli P., Chopra M., Rasanathan K. BMJ Global Health (2024) CC
Rising levels of inflation, debt and macrofiscal tightening are putting expenditures on the social sectors including health under immense scrutiny. Already, there are worrying signs of reductions in social sector investments. However, even before the pandemic, evidence showed the significant returns ... more
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Declaration by African Youth to End Malaria in Africa by 2030

RBM Partnership to End Malaria (2023) C2
​The Declaration by African Youth to End Malaria in Africa by 2030 is a commitment from young people across Africa to eradicate malaria by the year 2030. In this document, they outline specific strategies and actions they pledge to undertake, emphasizing the importance of youth involvement in mala ... more
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Declaration for accelerated malaria mortality reduction in Africa

RBM Partnership to End Malaria (2024) C2
The “Declaration for Accelerated Malaria Mortality Reduction in Africa” is a statement signed by African health ministers reaffirming their commitment to reducing malaria-related mortality. It pledges strengthened leadership, increased domestic financing for malaria control programs, and the imp ... more
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Why Is There So Little Contractually Contingent Financing?

Dissanayake R. Center for Global Development (2024) CC
Most foreign aid comes in one of two forms: either we pay a person or an institution today in exchange for delivering some beneficial activity in the future, or we observe something bad happen to them and then give them support to recover from it. This kind of aid is simple to design and deliver, b ... more
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WHO guidelines on meningitis diagnosis, treatment and care. Web Annex B. Qualitative and economic evidence reports
recommended

World Health Organization WHO (2025) C_WHO
The guidelines are primarily intended for health-care professionals working in first- or second-level health-care facilities, including emergency, inpatient and outpatient services. They are also directed at policy-makers, health-care planners and programme managers, academic institutions, non-gover ... more
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Disability-inclusive Employment Promotion: Lessons learned from five GIZ projects

Deutsche Gesellschaft für Internationale Zusammenarbeit GIZ (2019) CC2
In the initial chapters, you will find different approaches that describe how to support job creation for entrepreneurs or employees who live with disabilities. The interventions are often initiated by the readiness to find and pick the right opportunities, such as an engaged entrepreneur or an open ... more
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Theory of Change

Nutrition and Food Security Alliance of Namibia; UNFPA; UNICEF; et al. (2020) CC2
Early Identification and Early Intervention Services for Young Children with Developmental Delays and Disabilities in Namibia Republic of Namibia Namibia Regional Consultations Report
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Message Guide for the Fight Against Malaria in Malawi

Ministry of Health of Malawi (2023) CC
This document was developed by the Ministry of Health in Malawi in collaboration with national and international partners. It introduces a Social and Behaviour Change (SBC) malaria message guide that is aligned with the National Malaria Communication Strategy (NMCS) for the period 2023–2030. The g ... more
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Lil Mosquito, Big Problem Campaign: Phase I

Breakthrough ACTION Guyana; Ministry of Health of Guyana; United States Agency for International Development USAID (2024) C1
Activity Brief.Formative research revealed that gold miners in remote regions of Guyana viewed malaria as an unavoidable and minor risk compared to other dangers. Building on these insights, Breakthrough ACTION co-created the 'Lil Mosquito, Big Problem' (LMBP) social and behavioural change campaign, ... more
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Current Developments in Malaria Vaccination: A Concise Review on Implementation, Challenges, and Future Directions

Sallam, M.; A.O.Al-Kathib, K.S.Al-Mazhoum, et al. Dove Press (2025) CC
Clinical Pharmacology: Advances and Applications, 2025:17 29–47
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Global research agenda on malaria vaccine introduction and implementation

World Health Organization WHO (2024) C_WHO
Technical Report
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Continuing malaria education modules: Module 1 Severe malaria—triage, diagnosis, and treatment

United States Agency for International Development USAID; U.S. President´s Malaria Initiative; Save the Children, et al. (2017) C1
The MalariaCare Toolkit. Tools for maintaining high-quality malaria case management services. Developed by MalariaCare, this module supports health supervisors in improving the management of severe malaria by providing focused, case-based learning and mentorship. It provides clinical supervisors w ... more
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National Strategic Plan for Malaria Elimination in Bangladesh: 2021-2025

National Malaria Elimination Programme - Directorate General of Health Services Ministry of Health & Family Welfare - Government of Bangladesh (2021) C2
The National Strategic Plan for Malaria Elimination 2021–2025 outlines Bangladesh’s roadmap to achieve zero indigenous malaria cases by 2030, with an interim goal to reduce transmission to near-zero levels by 2025. The strategy builds upon earlier successes in malaria control and shifts focus to ... more
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Systematic review of values and preferences for lenacapavir as pre-exposure prophylaxis and other forms of long-acting injectable PrEP
recommended

World Health Organization WHO (2025) C_WHO
Guidelines on lenacapavir for HIV prevention and testing strategies for long-acting injectable pre-exposure prophylaxis. Web Annex C
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Should HIV testing services with rapid diagnostic tests and/or self-tests be used for initiation or continuation of injectable long-acting PrEP?
recommended

World Health Organization WHO (2025) C_WHO
Guidelines on lenacapavir for HIV prevention and testing strategies for long-acting injectable pre-exposure prophylaxis. Web Annex D
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Declaration for accelerated malaria mortality reduction in Africa: commitment that “No one shall die from malaria”

Ministers of Health of High Burden High Impact (HBHI) Countries in Africa (2024) CC
Issued by the Ministers of Health of High Burden High Impact (HBHI) countries in Africa. Yaounde Declaration. Ministers committed to strengthening their health systems, stepping up domestic resources, enhancing multisectoral action and ensuring a robust accountability mechanism,” notes Dr Daniel ... more
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Analytical Fact Sheet: Diabetes, a silent Killer in Africa

Integrated African Health Observatory iAHO; World Health Organization African Region (2023) C_WHO
Diabetes is an increasingly prevalent yet under-recognised health crisis in Africa, driven by demographic and socioeconomic transitions. In 2021, 24 million adults in the region were living with diabetes, and this figure is expected to increase by 129% by 2045.
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Country guidance for planning triple elimination of mother-to-child transmission of HIV, syphilis and hepatitis B virus programmes

World Health Organization WHO (2025) C_WHO
This publication provides guidance for planning country-specific programming to achieve the triple elimination of mother-to-child (or vertical) transmission of HIV, syphilis and hepatitis B virus. It is based on the WHO Triple Elimination Framework, which promotes an integrated, person-centred appro ... more