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On 4 September 2025, the Ministry of Health of the Democratic Republic of the Congo (DRC) declared an outbreak of Ebola Virus Disease (EVD) in Kasai Province, following confirmation of Zaire ebolavirus by the National Institute of Biomedical Researc
...
h (INRB) in Bulape and Mweka Health Zones. As of 19 September, there have been 48 total cases (38 confirmed, 10 probable) with 31 deaths (21 confirmed, 10 probable) and a CFR of 64.5%. Among laboratory confirmed cases, 16 deaths were recorded (CFR: 45.7%). Four deaths occurred among health workers, underscoring the risk of nosocomial transmission. Most cases (39.7%) are among adults aged 20 years and above, in a densely populated, remote, and under-resourced area.
The outbreak is driven by multiple risk factors, including transmission in health facilities with limited infection prevention and control (IPC) measures and personal protective equipment (PPE), incomplete contact tracing, delayed detection, and unsafe burial practices. High population mobility between Bulape and Tshikapa, reliance on traditional healers, and the concurrent mpox outbreak are further straining the fragile health system and increasing the risk of geographic spread.
more
Building on the WHO guidelines for disclosure to children up to age 12 in 2011, this implementation guidance provides evidence on existing interventions that support children and adolescents living with HIV in the process of disclosure. It includes interventions that focuses on safe disclosure, as w
...
ell as supporting children and adolescents with onwards disclosure. Specifically, this brief collates existing interventions via a scoping review; assesses key interventions through a realist evaluation lens, identifying what works, for whom, and in what contexts; and highlights emerging considerations, key gaps, and key actions.
more
This brief report summarizes recent information on HIV drug resistance (HIVDR) in the era of integrase-strand transfer inhibitors (INSTI) for HIV prevention and treatment.
Adolescents and young adults aged 10-24 remain underserved in the global response against HIV. Combination prevention, treatment and care programmes use a mix of evidence-based interventions to meet the current HIV prevention needs of adolescents and young adults. However, there needs to be a focus
...
on priority interventions that are evidence-based, practical, contextual and sustainable. This document highlights interventions and recommendations that have passed through the evidence-based lens of the WHO.
more
Operational Guidance. This operational guidance provides a structured approach to support countries in sustaining priority services for HIV, viral hepatitis and sexually transmitted infections in the context of reduced external funding. The guidance is intended for national governments, public
...
health programmes, community-led organizations, civil society, technical partners and donors working to safeguard priority services, support phased adaptation, protect health outcomes and preserve hard-won gains.
more
Policy information sheet
These 2025 guidelines respond to the need for better approaches to identify advanced HIV disease, improve the poor outcomes of people living with HIV being discharged from hospital and provide updated guidance for treatment for Kaposi’s sarcoma through evidence-informed recommendations. The public
...
ation contains recommendations that are from previously published WHO guidelines documents on advanced HIV disease and introduces new recommendations that were developed in 2025.
more
Ces orientations opérationelles ont pour but de soutenir les pays dans le processus d’introduction d’un antibiotique. Leur objectif est de garantir un accès rapide aux antimicrobiens et l’utilisation appropriée de ces produits ainsi que des résultats optimaux pour les patients, tout en ré
...
duisant le risque de résistance émergente, en offrant des conseils sur la manière d’introduire un antibiotique dans les systèmes de santé nationaux. Elles se concentrent principalement sur les antibiotiques relevant des groupes de classification « Watch » (utilisation sélective) et « Reserve » (dernier recours), qui sont généralement utilisés comme traitements de deuxième et troisième intention en milieu hospitalier. Ceux-ci sont essentiels pour traiter les organismes multirésistants mais sont souvent confrontés à des difficultés spécifiques en matière d’accès, en particulier dans les pays à revenu faible ou intermédiaire. Les présentes orientations décrivent une approche de planification pour l’introduction et la mise en oeuvre de ces produits, en tenant compte de leurs caractéristiques uniques et des besoins connexes, dans le but d’améliorer l’accès au traitement pour les patients et de promouvoir globalement l’utilisation appropriée des antibiotiques.
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This technical brief describes promising models that demonstrate how FBOs could contribute to expanded access to improved HIV and other services for men. These models incorporate a range of WHO-recommended interventions and highlights operational considerations and key success factors. By capitalizi
...
ng on their strengths, FBOs can potentially serve as useful platforms for engaging men and other priority populations, promoting greater demand, uptake, and retention in care.
more
The WHO publication “Surveillance, case investigation and contact tracing for mpox: interim guidance” provides updated global technical guidance on monitoring and responding to mpox (formerly known as monkeypox). It explains how countries should conduct surveillance to detect new outbreaks, car
...
ry out case investigation including clinical assessment and lab specimen collection, and perform contact tracing to monitor people exposed to confirmed or probable cases in order to stop transmission and protect at-risk groups. The guidance includes practical recommendations for how long contacts should be monitored (e.g., daily for 21 days without requiring quarantine if symptom-free) and advising good hygiene and reduced exposure risk during the monitoring period. This interim guidance is intended to support public health authorities worldwide in strengthening mpox outbreak detection, response, and reporting.
more
This guide aims to support the implementation of evidence-based practices to reduce morbidity and mortality due to postpartum haemorrhage (PPH). Implementation is a multidisciplinary process that requires engagement from multiple stakeholders. Furthermore, implementation can and should be pursued in
...
a systematic and evidence-based manner.
This Implementation guide presents a structured process that will aid countries in their efforts to incorporate the latest PPH recommendations into national PPH guidelines and clinical practice.
more
A guide for training at a village and clinic level
Preparedness and response to bacterial meningitis outbreaks: toolkit for frontline healthcare workers
recommended
Designed as a suite of job aids on acute bacterial meningitis, this document serves as a resource for frontline healthcare professionals globally, including in settings where the risk of outbreaks and excess mortality is highest. With a primary focus on acute bacterial meningitis in children aged ov
...
er 1 month, adolescents and adults, the toolkit provides clinical guidance on the causative pathogens, clinical manifestations, diagnostic investigations, antibiotic therapy, adjunctive treatment, supportive care, post-exposure antibiotic prophylaxis, and infection prevention and control in healthcare settings.
more
The purpose of this interim guidance is to provide recommendations for planning and implementing RCCE activities that protect and empower communities during MVD outbreaks. The guidance is designed for national and subnational health responders invol
...
ved in RCCE for MVD readiness and response. It is also relevant to other stakeholders, such as partner organizations, ministries (such as those involved in social protection), and academics, who contribute to RCCE activities. The document is meant to be adapted alongside national multi-risk/ multisectoral plans, leveraging existing expertise, coordination mechanisms and partnerships.
more
The revised guidelines contain recommendations for specific administrative, environmental controls and respiratory protection, following the assessment made by an external group of experts convened as members of the Guideline Development Group. Moreover, these guidelines focus on interventions speci
...
fic to preventing transmission of Mycobacterium tuberculosis bridging with the core components of infection prevention and control programmes at the national and acute health care facility level
more
В этом руководстве использован комплексный подход к укреплению системы здравоохранения на границах с целью оказания поддержки национальным координационным цент
...
рам по ММСП и другим национальным учреждениям в разработке и осуществлении основанных на фактических данных планов действий по развитию возможностей по ММСП в пунктах пересечения границы. Этот подход включает в себя перемещение лиц, совершающих поездки, и багажа, грузов, контейнеров, перевозочных средств, товаров и почтовых посылок через наземные переходы, а также взаимодействие с соседними пограничными сообществами. При необходимости в ходе оценки риска могут учитываться и другие факторы.
Переведено с помощью www.DeepL.com/Translator (бесплатная версия)
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This guidance provides interim guidance for the integration of SARS-CoV-2 and influenza virologic and genomic surveillance, from sentinel site case enrolment and sampling to the eventual sharing of the virus sequence data, a process known as end-to-end surveillance. This guidance builds on experienc
...
es and lessons learned as countries adapted their influenza surveillance systems in the context of the COVID-19 pandemic and reviews new evidence to provide guidance on end-to-end surveillance. The guidance includes new algorithms and strategies to adapt sentinel systems to make them resilient and agile for addressing global and national surveillance needs for influenza and COVID-19.covid-
more
These guidelines present evidence-based recommendations and best practice statements on use of medically important antimicrobials in food-producing animals, based on the WHO list of critically important antimicrobials for human medicine (WHO CIA List). These guidelines aim primarily to help preserve
...
the effectiveness of medically important antimicrobials, particularly those antimicrobials judged to be critically important to human medicine and also help preserve the effectiveness of antimicrobials for veterinary medicine, in direct support of the WHO global action plan on antimicrobial resistance
more
To provide a foundation for the strategic policy and programme development needed to ensure the sustainable implementation of effective interventions for reducing the global burden of PPH
