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Target product profile for a point-of-care diagnostic test for dermal leishmaniases - Control of Neglected Tropical Diseases

World Health Organization World Health Organization WHO (2022) C_WHO

Localized cutaneous leishmaniasis and its evolving forms (diffuse cutaneous leishmaniasis, mucosal leishmaniasis and cutaneous leishmaniasis recidivans), together with the sequela of visceral leishmaniasis (post-kala-azar dermal leishmaniasis), acco ... more

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The Sphere Handbook. Interactive Version
recommended

The Sphere Project (2019) CC

Sphere has recently updated its Interactive Handbook, making it quicker and easier to browse and access its content. New features allow users to browse the Handbook in multiple languages, access ad ... more

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Therapeutics and COVID-19 (Living Guideline, 10 November 2023)

World Health Organization WHO (2023) C_WHO

WHO has updated its guidelines for COVID-19 therapeutics, with revised recommendations for patients with non-severe COVID-19. This is the 13th update to these guidelines. Updated risk rates for hospital admission in patients with non-severe COVID ... -19 The guidance includes updated risk rates for hospital admission in patients with non-severe COVID-19. The current COVID-19 virus variants tend to cause less severe disease while immunity levels are higher due to vaccination, leading to lower risks of severe illness and death for most patients. This update includes new baseline risk estimates for hospital admission in patients with non-severe COVID-19. The new ‘moderate risk’ category now includes people previously considered to be high risk including older people and/or those with chronic conditions, disabilities, and comorbidities of chronic disease. The updated risk estimates will assist healthcare professionals to identify individuals at high, moderate or low risk of hospital admission, and to tailor treatment according to WHO guidelines: **High: **People who are immunosuppressed remain at higher risk if they contract COVID-19, with an estimated hospitalization rate of 6%. **Moderate: **People over 65 years old, those with conditions like obesity, diabetes and/or chronic conditions including chronic obstructive pulmonary disease, kidney or liver disease, cancer, people with disabilities and those with comorbidities of chronic disease are at moderate risk, with an estimated hospitalization rate of 3%. Low: Those who are not in the high or moderate risk categories are at low risk of hospitalization (0.5%). Most people are low risk. Review of COVID-19 treatments for people with non-severe COVID-19 WHO continues to strongly recommend nirmatrelvir-ritonavir (also known by its brand name ‘Paxlovid’) for people at high-risk and moderate risk of hospitalization. The recommendations state that nirmatrelvir-ritonavir is considered the best choice for most eligible patients, given its therapeutic benefits, ease of administration and fewer concerns about potential harms. Nirmatrelvir-ritonavir was first recommended by WHO in April 2022. If nirmatrelvir-ritonavir is not available to patients at high-risk of hospitalization, WHO suggests the use of molnupiravir or remdesivir instead. WHO suggests against the use of molnupiravir and remdesivir for patients at moderate risk, judging the potential harms to outweigh the limited benefits in patients at moderate risk of hospital admission. For people at low risk of hospitalization, WHO does not recommend any antiviral therapy. Symptoms like fever and pain can continue to be managed with analgesics like paracetamol. WHO also recommends against use of a new antiviral (VV116) for patients, except in clinical trials. The update also includes a strong recommendation against the use of ivermectin for patients with non-severe COVID-19. WHO continues to advise that in patients with severe or critical COVID-19, ivermectin should only be used in clinical trials. more

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Snakebite envenoming: Snakebite Information and Data Platform

World Health Organization World Health Organization WHO (2023) C_WHO

As part of its 2019–2030 global strategy for the prevention and control of snakebite envenoming, WHO is launching a new Snakebite Information and Data Platform. This is the result of collaboration between the Departments of Control of Neglected Tr ... more

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Emergency Appeal - Kenya April - September 2020

UN Office for the Coordination of Humanitarian Affairs; Humanitarian Response et al. (2020) C2

Kenya reported its first case of COVID-19 on 12 March 2020 and, as at 7 April 2020, 172 cases had been confirmed and 6 deaths reported. The Government of Kenya has taken a number of measures to curb the spread of the virus, including implementing a ... more

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Polio transition planning and polio post-certification: Report by the Director-General

World Health Organization WHO (2022) C_WHO

The Executive Board at its 150th session noted an earlier version of this report.1 The present report provides an update on the implementation of the Strategic Action Plan on Polio Transition (2018–2023)2 at the start of 2022, within the context o ... more

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Hidden in Plain Sight: A statistical analysis of violence against children

United Nations Children's Fund (UNICEF) (2014)

Interpersonal violence – in all its forms – has a grave effect on children: Violence undermines children’s future potential; damages their physical, psychological and emotional well-being; and in many cases, ends their lives. The report sheds ... more

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Safe Strong & Smiling. 20 Messages for Children to Learn and Share

Children for Health (2018) CC

This Ebola Poster with its 20 Messages was developed with people working with children in schools in Sierra Leone during the Ebola crisis in 2014. It has been adapted in 2018. CfH has 100 other messages for children to learn and share in 10 health t ... more

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Chagas Clinical Research Platform Newsletter

Drugs for Neglected Diseases Initiative DNDi Latin America (2022) CC

To support its R&D activities on Chagas disease, DNDi launched the Chagas Clinical Research Platform (CCRP). The platform brings together partners, experts, and stakeholders to provide support for evaluation and development of new treatments for Cha ... more

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Renewable energy solutions improve children’s health and wellbeing in Malawi

Unicef (2021) C_UNICEF

UNICEF Malawi and its partners are prioritizing renewable energy solutions for children and communities across the country to access clean and affordable electricity, with a focus on hard-to-reach, rural communities unable to access the national ele ... more

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Learn more about monkeypox as we record first confirmed case in SA

Saphra (2022) CC

South Africa has recorded its first case of monkeypox today, 23 June 2022. The Minister of Health Dr. Joe Phaahla explained that he received a report from the National Health Laboratory Services’ CEO that they have confirmed through laboratory t ... more

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Profiles of Peripheral CD4+T Cells Count during Antiretroviral Treatment in Senegalese Adults Infected by HIV: Impact of Therapeutic Associations

Niang M. S., R. Derwiche, B. Mbengue Journal of Immunology, Infection & Inflammatory Diseases (2017) CC

Thirty-three years after its discovery, the Human Immunodeficiency Virus (HIV), responsible for the AIDS pandemic, remains a major public health problem despite advanced researches providing better diagnostic and therapeutic tools. The virus targets ... more

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Catholic Social Teaching

Caritas Australia (2021) CC

With human dignity at its centre, a holistic approach to development founded on the principles of CST, is what Pope Paul VI called ‘authentic development’. Explore the Catholic Social Teaching principles and how they guide our work

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Syria: 2016 Humanitarian Response Plan Monitoring Report, January-June 2016

UN Office for the Coordination of Humanitarian Affairs (2016) C1

Now entering its sixth year, the conflict in Syria continues to take a drastic toll on the lives of the Syrian people and to drive an unprecedented humanitarian and protection crisis: some 13.5 million people are now in need of humanitarian assistan ... more

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Gender in Humanitarian Action Brief No. 5. Rohingya Refugee Crisis Response - Cox’s Bazar, Bangladesh (July 2018)

Inter Sector Coordination Group (ISCG) (2018) C1

UNHCR and its partners implement interventions focusing on adolescent girls and boys, including:
▪ Formation and capacity building of adolescent girls and boys’ clubs as peer groups for awareness raising, and SGBV prevention and response me ... more

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Country Office Annual Report 2020 Namibia - Update on the context and situation of children

UNICEF (2021) C_UNICEF

Namibia recorded its first COVID-19 case on 14 March 2020, with cumulative cases reaching 15,773 and 118 deaths by 10 December 2020. Namibia has done relatively well to contain the outbreak. However, positivity rates have shown a consistent increas ... more

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What next for UK development assistance under the next government?

Buse K., McKee M. British Medical Journal (BMJ) (2024) CC

The UK could regain its leadershipin the provision of development assistance for healthunder the next government. But this doesn’t seem likely if the party manifestos are any guide.

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Burundi Regional Refugee Response Plan: January - December 2018

United Nations High Commissioner for Refugees (UNHCR) (2017) C1

As the Burundi refugee crisis enters its fourth year, some 430,000 Burundian refugees are being hosted across the region by the governments and people of Tanzania, Rwanda, the Democratic Republic of the Congo, and Uganda. Although the spectre of mas ... more

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Myanmar (Burma): Disaster Management Reference Handbook

Center for Excellence in Disaster Management and Humanitarian Assistance (2017) C1

Myanmar has made significant progress in its disaster management policies, plans, and procedures since 2008, when Cyclone Nargis impacted the country leaving devastation in its aftermath. The Govern ... more

The Sphere Handbook. Interactive Version recommended

The Sphere Handbook. Interactive Version
recommended