This document provides information and recommendations for action, based on the current available knowledge around monkeypox. It is a first draft which will be updated in light of evolving evidence and additional information as they become available.
The development of this target product profile (TPP) was led by the WHO Department of Control of Neglected Tropical Diseases (NTD) following standard WHO guidance for TPP development. In order to identify and prioritize diagnostic needs, a WHO NTD Diagnostics Technical Advisory Group (DTAG) was form...ed, and different subgroups were created to advise on specific NTDs, including a subgroup working on the human African trypanosomiasis (HAT) diagnostic innovation needs. This group of independent experts included leading scientists, public health officials and endemic-country end-user representatives. Standard WHO Declaration of Interest procedures were followed. A landscape analysis of the available products and of the development pipeline was conducted, and the salient areas with unmet needs were identified.
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Onchocerciasis – or “river blindness” – is a parasitic disease caused by the filarial worm Onchocerca volvulus transmitted by repeated bites of infected blackflies (Simulium spp.). These blackflies breed along fast-flowing rivers and streams, close to remote villages located near fertile lan...d where people rely on agriculture.
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Human scabies is caused by an infestation of the skin by the human itch mite (Sarcoptes scabiei var. hominis). The microscopic scabies mite burrows into the upper layer of the skin where it lives and lays its eggs.
Scabies is found worldwide and affects people of all races and social classes. Scabi...es can spread rapidly under crowded conditions where close body and skin contact is frequent. Institutions such as nursing homes, extended-care facilities and prisons are often sites of scabies outbreaks. Child care facilities also are a common site of scabies infestations.
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About six to seven million people worldwide, mostly in Latin America, are estimated to be infected with
Trypanosoma cruzi, the parasite that causes Chagas disease (WHO data from 2021). Chagas disease is
found mainly in endemic areas of 21 Latin American countries.
Leishmaniasis is a parasitic disease that is found in parts of the tropics, subtropics, and southern Europe. Leishmaniasis is caused by infection with Leishmania parasites, which are spread by the bite of infected sand flies. There are several different forms of leishmaniasis in people. The most com...mon forms are cutaneous leishmaniasis, which causes skin sores, and visceral leishmaniasis, which affects several internal organs (usually spleen, liver, and bone marrow).
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Es una enfermedad muy contagiosa que se transmite a través de las gotitas de saliva que
viajan por el aire cada vez que alguien enfermo tose, estornuda, escupe, habla o canta.
Los microbios hacen agujeros en los pulmones y pueden causar la muerte.
Anaesthesia Tutorial of the Week
apoyar la incidencia al más alto nivel y el desarrollo de
capacidades de reducción del riesgo de desastre (RRD) y
resiliencia centrada en los niños, niñas, adolescentes y
jóvenes, desde una perspectiva holística, multi-sectorial
integrada y sistemática.
Quick reference guide on clinical management of patients with Dengue
Quick reference guide on clinical management of patients with Dengue Fever