Accelerating towards a leprosy-free world
The Guidelines for the Diagnosis, Treatment and Prevention of Leprosy provide state-of-the-art knowledge and evidence on leprosy diagnosis, treatment and prevention based on a public health approach in endemic countries. The target audience of this document includes policy-makers in leprosy or infec...tious diseases in the ministries of health (especially but not limited to endemic countries), nongovernmental organizations, clinicians, pharmaceutical companies, donors and affected persons
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In case of resistance to rifampicin, fluoroquinolones become the preferred category of second-line drugs. Unfortunately, quinolone-resistant strains of Mycobacterium leprae have also been reported in several countries, probably due to the extensive use of quinolones for treating several types of inf...ections. Clofazimine resistance is still rare but this antimicrobial cannot be given alone
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BMC International Health and Human Rights 2012, 12 :12
http://www.biomedcentral.com/1472-698X/12/12
Ce manuel est destiné aux formations sanitaires de base afin qu’elles puissent faire face à la lutte contre la lèpre au Rwanda en s’alignant à la Stratégie mondiale renforcée telle que définie par l’OMS1. Cette stratégie de l’OMS et ses partenaires a pour but de réduire davantage la... charge de la lèpre, et fournir des services de qualité pour le traitement de la maladie dans toutes les communautés affectées, tout en garantissant le respect des principes d’équité et de justice sociale.
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Third Edition: Revised October 2012
Weekly epidemiological record/Relevé épidémiologique hebdomadaire , 1ST SEPTEMBER 2017, 92th YEAR / no.35 (2017) 501-520
Weekly epidemiological record; Relevé épidémiologique hebdomadaire 10 SEPTEMBER 2021, 96th YEAR / 10 SEPTEMBRE 2021, 96e ANNÉE No 36, 2021, 96, 421–444
This chapter discusses the antibacterial treatment of leprosy infections. Antibiotic treatment is
a key component of leprosy treatment, as it is vital to prevent the progression of the infection.
Treatment with rifampin and other antibiotics is highly effective and cures 98% of patients with
the ...leprosy infection. Furthermore, the relapse rate is very low, at about 1% over 5–10 years.
There is little M. leprae drug resistance in leprosy and few reports of multi-drug resistance (1, 2, 3,
4, 5, 6, 7, 8). An antibiotic treatment may take months or years to produce clinical improvement,
especially in patients with an initial high bacterial index (BI).
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