Since the description of the first case of COVID-19 in Wuhan, Hubei province in China, in December 2019, much knowledge has been accumulated about the dynamics of evolution of the SARS-CoV-2 virus, contagion, disease progression, prevention and treatment.
Solidarity” is an international clinical trial to help find an effective treatment for COVID-19, launched by the World Health Organization and partners.
The Solidarity Trial will compare four treatment options against standard of care, to assess their relative effectiveness against COVID-19. By... enrolling patients in multiple countries, the Solidarity Trial aims to rapidly discover whether any of the drugs slow disease progression or improve survival. Other drugs can be added based on emerging evidence.
Until there is sufficient evidence, WHO cautions against physicians and medical associations recommending or administering these unproven treatments to patients with COVID-19 or people self-medicating with them. WHO is concerned by reports of individuals self-medicating with chloroquine and causing themselves serious harm.
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Development of cardiovascular disease (CVD) is influenced by risk factors such as:
tobacco use, an unhealthy diet, physical inactivity, obesity (which can result from
a combination of unhealthy diet, physical inactivity, and other factors), elevated
blood pressure (hypertension), abnormal blood l...ipids (dyslipidaemia) and elevated blood glucose (diabetes mellitus). Continuing exposure to these risk factors leads
to further progression of atherosclerosis, resulting in clinical manifestations of these diseases, including angina pectoris, myocardial infarction, heart failure and stroke. Total CVD risk depends on the individual’s overall risk-factor profile.
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The article discusses chronic obstructive pulmonary disease (COPD) as a common but under-recognized occupational disease. While smoking is the main cause, occupational exposure to vapors, gases, dusts, and fumes (VGDF) significantly contributes to the development and progression of COPD. Epidemiolog...ical studies indicate that up to 14% of COPD cases are attributable to occupational factors. The article highlights the need for better physician training in obtaining occupational exposure histories and emphasizes early diagnosis to prevent disease progression. Additionally, it stresses the importance of collaboration among general practitioners, respiratory specialists, and occupational health professionals to reduce the health and socio-economic impact of COPD.
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Cette note d'information souligne l'importance d'intégrer une approche sensible au genre dans les efforts de lutte contre le paludisme dans le monde entier. Il montre que la prise en compte des vulnérabilités et des besoins spécifiques à chaque sexe - en particulier ceux des femmes et des enfan...ts - peut produire un « double dividende » en améliorant les résultats sanitaires et en faisant progresser l'égalité entre les sexes
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Ainsi, le présent profil peint le faciès épidémiologique du pays pour l’année 2015
avec un clin d’œil sur le niveau de réalisation des Objectifs du millénaire pour le
développement (OMD) et un focus particulier sur l’appropriation des Objectifs de
développement durable (ODD). Il e...st composé de six chapitres que sont (i)
Introduction au contexte du pays ; (ii) Etat et tendance des indicateurs de santé ; (iii)
Système de santé ; (iv) Progrès des objectifs de développement durable ; (v)
Programmes et services spécifiques ; (vi) Déterminants clés de la santé.
C’est un outil recommandé par l’OMS et est indispensable pour le pays en prélude à
la mise en place de l’Observatoire national de la santé. Son élaboration a connu un
processus participatif avec l’implication des différents acteurs intervenant dans le
domaine de la santé.
Profil sanitaire complet du Burkina Faso 2015 Page 8
Le document du profil pays a été organisé en 4 modules à savoir :
Module 1 : La situation socio-sanitaire du Burkina Faso et mise en œuvre des ODD ;
Module 2 : Le Système de santé au Burkina Faso ;
Module 3 : Les programmes et services spécifiques de santé au Burkina Faso ;
Module 4 : Les déterminants clés de la santé
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La publication des résultats de l’EDSC-V intervient quelques années seulement après l’échéance en 2015 des Objectifs du millénaire pour le développement (OMD), le lancement de l’Agenda 2065 de l’Union Africaine, de l’Agenda 2030 des Nations Unies pour le Développement Durable, et a...u moment de la finalisation de la
Stratégie nationale de développement de la deuxième génération (2020-2027) dans le cadre de la Vison 2035.Nul doute qu’ils serviront à établir la situation finale ou la situation de référence pour le suivi évaluation des progrès accomplis dans le cadre de ces agendas nationaux et internationaux.
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Afin de mesurer le niveau et les tendances des indicateurs relatifs à la situation des enfants et des femmes, l'UNICEF a élaboré, depuis les années 1990, le programme mondial des enquêtes MICS. Ce programme international permet une comparabilité des indicateurs entre les différents pays. Cett...e enquête dénommé MICS Urbaine Dakar fait suite aux MICS1 et MICS2 réalisées respectivement en 1996 et 2000. Les résultats présentés dans ce rapport constituent à la fois une évaluation des progrès réalisés dans le respect des engagements convenus au niveau international par l’Etat du Sénégal, et une situation de référence pour le suivi des Objectifs de Développement Durable à l’horizon 2030.
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Les Perspectives mondiales de la biodiversité (PMB) sont la publication phare de la Convention sur la diversité biologique (CDB). Il s'agit d'un rapport périodique qui résume les dernières données sur l'état et les tendances de la biodiversité et tire des conclusions pertinentes pour la pour...suite de la mise en œuvre de la Convention.
Le GBO-5 fournit un résumé mondial des progrès accomplis en vue de la réalisation des objectifs d'Aichi en matière de biodiversité et se fonde sur une série d'indicateurs, d'études de recherche et d'évaluations (en particulier l'évaluation mondiale de la biodiversité et des services écosystémiques de l'IPBES), ainsi que sur les rapports nationaux fournis par les pays sur leur mise en œuvre de la CDB. Les rapports nationaux fournissent de riches informations sur les mesures prises dans les pays du monde entier en faveur de la conservation de la biodiversité, de son utilisation durable et du partage juste et équitable des avantages. Ce corpus d'informations fournit une foule de renseignements sur les réussites et les difficultés de la mise en œuvre du Plan stratégique pour la biodiversité 2011-2020 et de la réalisation des objectifs d'Aichi en matière de biodiversité.
Ces Perspectives s'appuient sur les enseignements tirés des deux premières décennies de ce siècle pour clarifier les transitions nécessaires si nous voulons concrétiser la vision convenue par les gouvernements mondiaux pour 2050, "Vivre en harmonie avec la nature".
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La evidencia disponible a nivel internacional sobre el uso de un segundo refuerzo muestra una mayor duración de la respuesta inmune y una disminución de la internación y la mortalidad por COVID 19 en la población de adultos mayores y huéspedes inmunocomprometidos. Por otra parte, el personal de... salud se beneficiaría considerando el mayor riesgo de exposición y la caída de la respuesta inmune con el tiempo. En base a lo señalado previamente se recomienda incorporar y
priorizar un segundo refuerzo al esquema de vacunación contra la COVID-19 del:
- Personal de salud independientemente de la edad
- Personas de 50 años o mayores
- Personas de 12 años o más con inmunocompromiso
A la vez, se progresará de manera escalonada y simultánea con la vacunación de segundo refuerzo del:
- Personal estratégico
- Personas de 18 a 49 años con factores de riesgo
Continuando en la estrategia de segundo refuerzo todas las personas a partir de los 18 años. Las personas gestantes con indicación de segundo refuerzo, se recomienda vacunas de plataforma de ARNm (Pfizer-BioNTech o Moderna)
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Ainsi, le présent profil peint le faciès épidémiologique du pays pour l’année 2015
avec un clin d’œil sur le niveau de réalisation des Objectifs du millénaire pour le
développement (OMD) et un focus particulier sur l’appropriation des Objectifs de
développement durable (ODD). Il e...st composé de six chapitres que sont (i)
Introduction au contexte du pays ; (ii) Etat et tendance des indicateurs de santé ; (iii)
Système de santé ; (iv) Progrès des objectifs de développement durable ; (v)
Programmes et services spécifiques ; (vi) Déterminants clés de la santé.
C’est un outil recommandé par l’OMS et est indispensable pour le pays en prélude à
la mise en place de l’Observatoire national de la santé. Son élaboration a connu un
processus participatif avec l’implication des différents acteurs intervenant dans le
domaine de la santé.
Profil sanitaire complet du Burkina Faso 2015 Page 8
Le document du profil pays a été organisé en 4 modules à savoir :
Module 1 : La situation socio-sanitaire du Burkina Faso et mise en œuvre des ODD ;
Module 2 : Le système de santé au Burkina Faso ;
Module 3 : Les programmes et services spécifiques de santé au Burkina Faso ;
Module 4 : Les déterminants clés de la santé.
more
Ainsi, le présent profil peint le faciès épidémiologique du pays pour l’année 2015
avec un clin d’œil sur le niveau de réalisation des Objectifs du millénaire pour le
développement (OMD) et un focus particulier sur l’appropriation des Objectifs de
développement durable (ODD). Il e...st composé de six chapitres que sont (i)
Introduction au contexte du pays ; (ii) Etat et tendance des indicateurs de santé ; (iii)
Système de santé ; (iv) Progrès des objectifs de développement durable ; (v)
Programmes et services spécifiques ; (vi) Déterminants clés de la santé.
C’est un outil recommandé par l’OMS et est indispensable pour le pays en prélude à
la mise en place de l’Observatoire national de la santé. Son élaboration a connu un
processus participatif avec l’implication des différents acteurs intervenant dans le
domaine de la santé.
Profil sanitaire complet du Burkina Faso 2015 Page 7
Le document du profil pays a été organisé en 4 modules à savoir :
Module 1 : La situation socio-sanitaire du Burkina Faso et mise en œuvre des ODD ;
Module 2 : Le Système de santé au Burkina Faso ;
Module 3 : Les programmes et services spécifiques de santé au Burkina Faso ;
Module 4 : Les déterminants clés de la santé.
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Background
Asthma education, a key component of long-term asthma management, is challenging in resource-limited settings with shortages of clinical staff. Task-shifting educational roles to lay (non-clinical) staff is a potential solution. We conducted a randomised controlled trial of an enhanced a...sthma care intervention for children in Malawi, which included reallocation of asthma education tasks to lay-educators. In this qualitative sub-study, we explored the experiences of asthmatic children, their families and lay-educators, to assess the acceptability, facilitators and barriers, and perceived value of the task-shifting asthma education intervention.
Methods
We conducted six focus group discussions, including 15 children and 28 carers, and individual interviews with four lay-educators and a senior nurse. Translated transcripts were coded independently by three researchers and key themes identified.
Results
Prior to the intervention, participants reported challenges in asthma care including the busy and sometimes hostile clinical environment, lack of access to information and the erratic supply of medication. The education sessions were well received: participants reported greater understanding of asthma and their treatment and confidence to manage symptoms. The lay-educators appreciated pre-intervention training, written guidelines, and access to clinical support. Low education levels among carers presented challenges, requiring an open, non-critical and individualised approach.
Discussion
Asthma education can be successfully delivered by lay-educators with adequate training, supervision and support, with benefits to the patients, their families and the community. Wider implementation could help address human resource shortages and support progress towards Universal Health Coverage.
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The One Health (OH) High-Level Expert Panel (OHHLEP) of the Quadripartite Organizations defined OH as an integrated, unifying approach that aims to sustainably balance and optimize the health of people, animals and ecosystems.”
It recognizes the health of humans, domestic and wild animals, plan...ts, and the wider environment (including ecosystems) are closely linked and interdependent [1]. The Tripartite which comprised the Food and Agriculture Organization (FAO) of the United Nations (UN), the World Health Organization (WHO), and the World Organisation for Animal Health (WOAH) later became the Quadripartite organizations when the United Nations Environment Programme (UNEP) joined the OH alliance in 2022. There are Global and Regional Quadripartite Secretariats consisting of officials of headquarters and regional offices, respectively.
Over the years, the Tripartite/Quadripartite organizations and other partner agencies have developed several OH assessment and operational tools to support Member States in assessing their core capacities to achieve compliance with the requirements of international standards such as the International Health Regulations 2005 (IHR), WOAH’s Terrestrial and Aquatic Animal Health Codes, World Trade Organization’s Sanitary and Phytosanitary Measures (WTO-SPS), FAO/WHO Codex standards, etc. Technical areas that the existing tools currently support include progress monitoring, coordination and collaboration mechanisms, and capacity building for prevention, detection, preparedness, and response to health threats emerging at human-animal-environment interface. More OH B operational tools are in the pipeline.
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The International Rescue Committee (IRC) is a leading humanitarian agency dedicated to helping people whose lives have been shattered by conflict and disaster to survive, recover, and gain control of their future. Health comprises nearly half of IRC’s program portfolio globally and encompasses thr...ee sectors: 1) Primary Health (including child health, sexual and reproductive health and rights, and mental health); 2) Nutrition; and 3) Environmental Health. IRC health programming across its portfolio, in terms of the size and breadth, responds to significant needs in crisis affected settings, improving health and wellbeing while reducing causes of ill-health.
This five-year Health Strategy sharpens our focus on where we can have the most impact. It guides our efforts in planning, technical assistance, business development, advocacy, and internal and external collaboration. Through this strategy, we will invest and grow in areas that will help us achieve high impact at scale for our clients. For the next five years these priorities will include: Nutrition; Immunization: Infectious Disease Prevention and Control; Last Mile Delivery of Primary Health Care: Clean Water.
Our strategy aligns with Strategy 100 (S100) and Strategy Action Plans (SAPs). It lays out how IRC, through health, nutrition, and Environmental Health (EH) programming, will advance the IRC’s S100 ambitions, respond to global trends, and capitalize on our value add. The strategy will be complemented by delivery plans that detail investments, actions, and roles and responsibilities to advance our priorities. At the end of FY24, we will take stock of the implementation of the strategy, measure progress towards achieving our goals, and review if it continues to be fit for purpose.
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In 2015, the United Nations set important targets to reduce premature
cardiovascular disease (CVD) deaths by 33% by 2030. Africa disproportionately
bears the brunt of CVD burden and has one of the highest risks of dying
from non-communicable diseases (NCDs) worldwide. There is currently
an epide...miological transition on the continent, where NCDs is projected
to outpace communicable diseases within the current decade. Unchecked
increases in CVD risk factors have contributed to the growing burden of three
major CVDs—hypertension, cardiomyopathies, and atherosclerotic diseasesleading to devastating rates of stroke and heart failure. The highest age
standardized disability-adjusted life years (DALYs) due to hypertensive heart
disease (HHD) were recorded in Africa. The contributory causes of heart failure
are changing—whilst HHD and cardiomyopathies still dominate, ischemic
heart disease is rapidly becoming a significant contributor, whilst rheumatic
heart disease (RHD) has shown a gradual decline. In a continent where health
systems are traditionally geared toward addressing communicable diseases,
several gaps exist to adequately meet the growing demand imposed by CVDs.
Among these, high-quality research to inform interventions, underfunded
health systems with high out-of-pocket costs, limited accessibility and
affordability of essential medicines, CVD preventive services, and skill
shortages. Overall, the African continent progress toward a third reduction
in premature mortality come 2030 is lagging behind. More can be done in
the arena of effective policy implementation for risk factor reduction and
CVD prevention, increasing health financing and focusing on strengthening
primary health care services for prevention and treatment of CVDs, whilst
ensuring availability and affordability of quality medicines. Further, investing
in systematic country data collection and research outputs will improve the accuracy of the burden of disease data and inform policy adoption on
interventions. This review summarizes the current CVD burden, important
gaps in cardiovascular medicine in Africa, and further highlights priority
areas where efforts could be intensified in the next decade with potential
to improve the current rate of progress toward achieving a 33% reduction
in CVD mortality.
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The Event-based Surveillance Framework is intended to be used by authorities and agencies responsible for
surveillance and response. This framework serves as an outline to guide stakeholders interested in implementing
event-based surveillance (EBS) using a multisectoral, One Health approach. To ...that end, the document is arranged
in interlinked chapters and annexes that can be modified and adapted, as needed, by users.
This is a revised version of the original “Framework for Event-based Surveillance” that was published in 2018. This
framework does not replace any other available EBS materials, but rather builds on existing relevant or related
documents and serves as a practical guide for the implementation of EBS in Africa. This framework is aligned with
the third edition of the WHO Joint External Evaluation for the following indicators: strengthened early warning
surveillance systems that are able to detect events of significance for public health and health security (Indicator
D2.1); improved communication and collaboration across sectors and between National, intermediate and local
public health response levels of authority regarding surveillance of events of public health significance (Indicator
D2.2); and improved national and intermediate-level capacity to analyse data (Indicator D2.3). As countries begin
to implement and demonstrate EBS functionality they will ensure an increase in JEE scores and progress towards
meeting the requirements outlined in the IHR3F
Additionally, in African Union Member States that have adopted the Integrated Disease Surveillance and
Response (IDSR) strategy, this document is a complement to and can enhance the implementation of IDSR,
especially for the 3rd edition (2019) that includes components related to EBS.
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The WHO Global Antimicrobial Resistance and Use Surveillance System (GLASS) was launched in 2015 to foster AMR surveillance and inform strategies to contain AMR. The system started with surveillance of AMR in bacteria causing common human infections and has expanded its scope to include surveillance... of antimicrobial consumption (AMC), invasive fungal infections, and a One Health surveillance model relevant to human health. To meet future challenges, it is in continuous evolution to enhance the quality and representativeness of data to inform the AMR burden accurately. As of the end of 2022, 127 countries, territories and areas participate in GLASS.
The fifth GLASS report, produced in collaboration with Member States, summarizes 2020 data on AMR rates in common bacteria from countries, territories, and areas. The report brings new features, including analyses of population testing coverage or AMR trends. For the first time, the report presents 2020 data on AMC at the national level. A new interactive dashboard allow users to explore AMR and AMC global data, country profiles and download the data.
This report marks the end of the early implementation phase of GLASS. In addition to presenting data collected through the latest data call, this report provides a summary of five years of national AMR surveillance data contributed to GLASS from its initiation, presents AMR findings in the context of progress of country participation in GLASS and in global AMR surveillance coverage and laboratory quality assurance systems at (sub)national level.
Patterns of antimicrobial consumption are presented by country with a particular focus on antibacterials. The report also presents the antimicrobial consumption according to the WHO AWaRe antibiotic classification, for penicillins and cephalosporines. From a One Health perspective, the report presents antimicrobial consumption data in the human sector expressed in tons to allow a comparison with antimicrobial consumption from other sectors (not included in this report).
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To assess national-level responses to NCDs, WHO has implemented NCD country capacity surveys periodically since 2001. This report is the latest in that series. Since the first survey round, the NCD Country Capacity Survey (NCD CCS) has been conducted a further seven times, most recently in 2021. In ...the survey, completed by the NCD focal point within each country’s ministry of health or similar agency, countries are asked to report on the following topics relating to NCDs: (i) public health infrastructure, partnerships and multisectoral collaboration; (ii) policies, strategies and action plans; (iii) health information systems and surveillance; (iv) health system capacity for detection, treatment and care; and, added for 2021, (v) the impact of the COVID-19 pandemic on NCD-related resources and activities. The questionnaire is web-based and requires supporting documentation wherever possible. In the 2021 round, data were collected from May onwards, with the last survey responses arriving in September. Validation was carried out by WHO regional offices and WHO headquarters. Country responses to previous rounds of the survey were incorporated into the analysis to assess progress since 2010. Although all 194 Member States responded to the survey, data comparisons were restricted to the 160 countries that had responded to all rounds of the survey since 2010.
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Cardiovascular diseases (CVD) represent the highest burden of disease globally. Medicines are a critical intervention used to prevent and treat CVD. This review describes access to medication for CVD from a health system perspective and strategies that have been used to promote access, including pro...viding medicines at lower cost, improving medication supply, ensuring medicine quality, promoting appropriate use, and managing intellectual property issues. Using key evidence in published and gray literature and systematic reviews, we summarize advances in access to cardiovascular medicines using the 5 health system dimensions of access: availability, affordability, accessibility, acceptability, and quality of medicines. There are multiple barriers to access of CVD medicines, particularly in low- and middle-income countries. Low availability of CVD medicines has been reported in public and private healthcare facilities. When patients lack insurance and pay out of pocket to purchase medicines, medicines can be unaffordable. Accessibility and acceptability are low for medicines used in secondary prevention; increasing use is positively related to country income. Fixed-dose combinations have shown a positive effect on adherence and intermediate outcome measures such as blood pressure and cholesterol. We have a new opportunity to improve access to CVD medicines by using strategies such as efficient procurement of low-cost, quality-assured generic medicines, development of fixed-dose combination medicines, and promotion of adherence through insurance schemes that waive copayment for long-term medications. Monitoring progress at all levels, institutional, regional, national, and international, is vital to identifying gaps in access and implementing adequate policies.
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