Atherosclerotic lower-extremity peripheral artery disease (PAD) is increasingly recognized as an important cause of cardiovascular morbidity and mortality that affects more than 230 million people worldwide. Traditional cardiovascular risk factors, including advanced age, smoking, and diabetes, are ...strongly linked to an increase risk of PAD. Although PAD has been historically underappreciated compared to coronary artery disease and stroke, greater attention on PAD in recent years has led to important new epidemiologic insights in the areas of thrombosis, inflammation, dyslipidemia, and microvascular disease. In addition, the concept of polyvascular disease, or clinically-evident atherosclerosis in multiple arterial beds, is increasingly identified as a particularly malignant cardiovascular disease worthy of special clinical attention and further study. It is noteworthy that PAD may increase the risk of adverse outcomes in similar or even greater magnitude than coronary disease or stroke. In this review, we highlight important new advances in the epidemiology of PAD with a particular focus on polyvascular disease, emerging biomarkers, and differential risk pathways for PAD compared to other atherosclerotic diseases.
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Lancet Planet Health 2019; 3: 469–77
The report provides a brief introduction to patents and licences and their effect on the market for antiretroviral (ARV) medicines. It gives an overview of the patent landscape with respect to a select number of ARV medicines in developing countries as of April 2014. The focus is primarily on those ...ARVs that are recommended by the World Health Organization (WHO) as well as new ARVs that have either recently obtained regulatory approval or are in phase III clinical trials.
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The aim of this handbook is to provide network members and other laboratories involved in the diagnosis of tuberculosis, with an agreed list of key diagnostic methods and their protocols in various areas of TB diagnosis, ranging from microbiological diagnosis of active TB to the diagnosis of latent ...TB infection. This handbook offers a single source of reference by compiling all methods, with a strong focus on standard (reference) and evidence-based methods. In so doing, it will also contribute to the improvement of disease surveillance data for Europe.
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PQDx 0181-031-00
WHO PQ Public Report
March/2017, version 3.0
Malar J (2017) 16:174 DOI 10.1186/s12936-017-1808-x
Background: Since 2004, artemisinin-based combination therapy (ACT) has been the first-line treatment for uncomplicated malaria in Benin. In 2016, a medicine outlet survey was implemented to investigate the availability, price, and market share of... anti-malarial treatment and malaria diagnostics. Results provide a timely and important benchmark to measure future interventions aimed at increasing access to quality malaria case management services.
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orientations provisoires, 23 avril 2020
A thesis submitted for the Degree of Master of Theology at the South African Theological Seminary
The global coronavirus pandemic, which has brought death to hundreds of thousands and serious illness to millions more, also poses profound spiritual questions and real challenges to Christians everywhere.
The pandemic itself has become a fundamental test of our faith in God and God’s providence,... and it urges us to earnest re-examination of our relationship to God, each other, and the natural world.
In Healing the World, the World Council of Churches offers these eight Bible studies to facilitate our coming to terms—as individuals, groups, and communities of faith—with the loss, fear, and confusion engendered by the pandemic, and the bracing prospect of building the world anew.
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Discussions about climate change often focus on the future, but millions of children are experiencing its devastating impacts now. The scale of the crisis is huge, and growing fast. It is children that will bear the brunt of climate change, yet its impact on them is understudied, their voices are no...t being heard, and current solutions are woefully inadequate. It is a perfect storm that we must stop in its path – before it is too late.
Available in English, French, Spanish, Portuguese, Arabic
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Die Klimakrise stellt die größte Bedrohung der menschlichen Gesundheit im21. Jahrhundert dar. Die mit ihr
einhergehenden Umweltveränderungen, die unter anderem zu Hitzewellen, Überflutungen und Unterernährung durch
Ernährungsunsicherheit führen, wirken sich bereits heute negativ auf die Ge...sundheit einer großen Anzahl von Menschen aus.
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Review
S Afr Med J 2014;104(3):174-177. DOI: 10.7196/SAMJ.7968
This assessment seeks to better understand what types of legal migration pathways and other protection services Iraqi refugees and other migrants are aware of and attempt to access at different points during their migration journey. Furthermore, it highlights when, where and why Iraqi refugees and o...ther migrants fail to access protection services.
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This report serves as a background paper to five short studies Yemeni-international researcher tandems will jointly develop in the course of 2019. It places a particular focus on ‘peace requirements’, a term that seeks to draw attention to the manifold challenges to establishing stab...ility and building peace in Yemen and the resulting efforts which will be required. This report analyzes the current situation in Yemen by looking at social structures, current conflict dynamics, the role and situation of state institutions and external factors, and then moves on to focus on what is required to build peace in Yemen. In laying out these peace requirements, the report focuses on the following relevant sectors: economy, politics, culture and society, as well as security and justice. In a last step, it takes a look at the challenges to and capacities of five different actor groups in Yemen to address these needs: civil society, women, youth, the media and the private sector
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Over 244,000 displaced people remain in camps or camp-like situations in Kachin, Shan, Rakhine
and Kayin states. Children make up at least 50 per cent of this population, while women and„Myanmar: 2019 Humanitarian Needs Overview - Myanmar“. ReliefWeb. Zugegriffen 4. Januar 2019. https://reliefw...eb.int/report/myanmar/myanmar-2019-humanitarian-needs-overview.
children together make up about 77 per cent. This includes approximately 97,000 people in
Kachin, 8,800 in Shan and 10,300 in Kayin who remain displaced as a result of the armed conflict.
It also includes about 128,000 people in Rakhine, the vast majority of whom are stateless, who
were displaced as a result of the violence in 2012.
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This document was prepared in response to a need to review and potentially update the current recommendations for the antibiotic treatment of both inpatient and outpatient management of severe acute malnutrition (SAM). The current recommendations (Table 1) are based on guidelines published in 2013 i...n the WHO Pocketbook for Hospital Care for Children, and the 2013 update on SAM (outpatient management). The global threat of increasing antimicrobial resistance and new data on efficacy and safety profiles requires a re-review of the current evidence to ensure recommendations are the most appropriate. The evidence base for the use of antibiotics in children presenting with uncomplicated SAM has been recently enlarged.
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Mental health disorders remain widely under-reported — in our section on Data Quality & Definitions we discuss the challenges of dealing with this data. Figures presented in this entry should be taken as estimates of mental health disorder prevalence — they do not strictly reflect diagnosis data... (which would provide the global perspective on diagnosis, rather than actual prevalence differences), but are imputed from a combination of medical, epidemiological data, surveys and meta-regression modelling where raw data is unavailable. Further information can be found here.
Accessed April 15, 2019
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ESTA NOTA INFORMATIVA SUBSTITUI A NOTA INFORMATIVA Nº 11/2020-SE/GAB/SE/MS, DE 15 DE JUNHO DE 2020, QUE SUBSTITUIU A NOTA INFORMATIVANº 9/2020-SE/GAB/SE/MS, DE 20 DE MAIO DE 2020