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1
In most malaria-endemic countries, temperatures frequently exceed the recommended storage temperatures for malaria RDTs. Correct storage of the RDTs may be difficult, especially during transport and
...
in locations where air-conditioning is unavailable.
This publication is intended to support health personnel who use RDTs. It describes the basic principles for management and storage of RDT stock; outlines practical solutions for protecting RDTs against high temperatures during storage and transport; and describes how to manage waste generated from RDT use in health clinics and central and peripheral storage facilities.
more
Strict storage recommendations for insulin are difficult to follow in hot tropical regions and even more challenging in conflict and humanitarian emergency settings, adding an extra burden to the management of people with diabetes. According to phar
...
macopeia unopened insulin vials must be stored in a refrigerator (2–8°C), while storage at ambient temperature (25–30°C) is usually permitted for the 4-week usage period during treatment. In the present work we address a critical question towards improving diabetes care in resource poor settings, namely whether insulin is stable and retains biological activity in tropical temperatures during a 4-week treatment period. To answer this question, temperature fluctuations were measured in Dagahaley refugee camp (Northern Kenya) using log tag recorders. Oscillating temperatures between 25 and 37°C were observed. Insulin heat stability was assessed under these specific temperatures which were precisely reproduced in the laboratory. Different commercialized formulations of insulin were quantified weekly by high performance liquid chromatography and the results showed perfect conformity to pharmacopeia guidelines, thus confirming stability over the assessment period (four weeks). Monitoring the 3D-structure of the tested insulin by circular dichroism confirmed that insulin monomer conformation did not undergo significant modifications. The measure of insulin efficiency on insulin receptor (IR) and Akt phosphorylation in hepatic cells indicated that insulin bioactivity of the samples stored at oscillating temperature during the usage period is identical to that of the samples maintained at 2–8°C. Taken together, these results indicate that insulin can be stored at such oscillating ambient temperatures for the usual four–week period of use. This enables the barrier of cold storage during use to be removed, thereby opening up the perspective for easier management of diabetes in humanitarian contexts and resource poor settings.
more
High levels of storage iron may increase malaria susceptibility. This risk has not been investigated in semi-immune adolescents. We investigated whether baseline iron status of nonpregnant adolescent girls living in a high malaria transmission area
...
in Burkina Faso affected malaria risk during the following rainy season. For this prospective study, we analysed data from an interim safety survey, conducted six months into a randomised iron supplementation trial. We used logistic regression to model the risk of P. falciparum infection prevalence by microscopy, the pre-specified interim safety outcome, in relation to iron status, nutritional indicators and menarche assessed at recruitment.
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Practical hints are provided for mOPV1 storage and handling at the sub-district and health centre levels
Practical hints are provided for mOPV1 storage and handling at regional stores
Drugs and medical supplies are dispensed at the cutting edge level of the interface between the public health system and the people. Availability or lack of it brings either credit or discredit to the public health system. The primary reason for holding stocks of medicines and medical supplies in a
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proper scientific manner is to ensure continuous and uninterrupted availability to prevent stock-outs, especially of critical items of supply while at the same time ensuring that stocks of medicines do not get expired. An efficient inventory management is a pre-requisite for optimal stock management. It enables the management of health facilities to know the current pattern of consumption of drug trends over a period of time and also variances. The environmental control of the drugs and other medical supplies play an important role to keep the products' efficacy intact. Some medicines and vaccines need special storage temperature, otherwise, there may be wastage. The quality of the medicines can be adversely affected by poor storage, transportation and distribution. Thus, maintaining proper storage condition for health commodities is vital for ensuring their quality. So, by this training, CDMU wants to educate different people dealing with medicines and equip them for the roles they have to perform efficiently so that the wastage does not take place or can be minimized.
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Vaccine handling, storage and Transportation of Pfizer BioNTech
COVID-19 COMIRNATY® (Tozinameran)
This resource offers practical guidance in managing the supply chain, with emphasis on health comodities. The handbook is particularly useful for program managers who design, manage, and assess logistics system for health program. The document includes detailed information about the design and imple
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mentation of logistics management information systems and inventory control systems. It also covers quantification, procurement processes, as well as storage, transport and product selection
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Training on handling, storing and transporting Pfizer BioNTech COVID-19 Vaccine COMIRNATY® (Tozinameran)
recommended
4 August 2021. Currently, Pfizer BioNTech COVID-19 Vaccine COMIRNATY® (Tozinameran) is the only COVID-19 vaccine that should be stored and transported at -60ºC to -86ºC ultra-low temperature (ULT) conditions. Prior to use the vaccine can be transferred to -20ºC freezer or +2-8ºC refrigerator at
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the lower store levels and immunization service points. However, vaccine shelf life is affected when vaccine is transferred to a different storage temperature. Health workers in charge of managing the storage, transport and administration of the vaccine should be well trained to maintain vaccine quality. Good cold chain planning, strong management of vaccine supply, logistics and distribution, including installation and effective monitoring and evaluation of the performance of the storage equipment and infrastructure, are also necessary.
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This manual is part of a series of guides devised by the Oxfam Public Health Engineering Team to help provide a reliable water supply for populations affected by conflict or natural disaster. The equipment is designed to be used with any or all of the following Oxfam water equipment: Water Pumping e
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quipment, Water Storage equipment, Water Filtration equipment, Water Distribution equipment, Hand-dug Well equipment, and Water Testing Kit. All are designed using available, easily transported equipment which is simple, rapidly assembled, and fully self-contained, to provide an adequate, safe water supply at moderate cost. The principles used in these packages may often be useful in long-term development projects.
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A model quality assurance system for procurement agencies
World Health Organization
World Health Organization, United Nations Children's Fund, United Nations Development Programme, United Nations Populations Fund, World Bank
(2007)
C_WHO
This interagency report provides recommendations for assuring quality of medicines during key activities of country-level procurement agencies, namely prequalification of pharmaceutical products and manufacturers; purchase of pharmaceutical products; stora
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ge of pharmaceutical products; and distribution of pharmaceutical products.
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A technical guide for sputum smear microscopy, initiated by the International Union against Tuberculosis, is designed to be an easy to use reference standard for the collection, storage and transport of sputum specimens and for the examination of sp
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utum smears by direct microscopy. This edition includes updates addressing bio-safety and quality assurance aspects of sputum smear microscopy.
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This technical guideline has been prepared for the water supply operators to facilitate them identifying the risks of water contamination in source, treatment process, storage and distribution system, and the means to control these risks. The guidel
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ines have been prepared with extensive use of photograph to make it convenient for the water supply operators and mechanics who are working at different steps of a water supply system. Use of this document will help the water supply operators to supply safe water at consumer end
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These National Operational Guidelines for Viral Load Testing detail how routine viral load testing will be implemented at the facility level in India. They include frequency and interpretation of monitoring, sample collections, storage and transport
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ation, receipt of results, adherence counseling, and reporting requirements. Roles and responsibilities are outlined as well as turnaround time requirements.
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The Pocket Guide to Managing Contraceptive Supplies addresses one of
the most important components of any program that provides family
planning services—the logistics system that manages the delivery,
quality, and storage of contraceptive suppl
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ies. These supplies are
essential; without them, family planning services cannot be provided.
This guide is for the staff of family planning or health clinics who
manage contraceptive supplies and for the supervisor who oversees
these logistics activities. This booklet is not a complete logistics text;
its purpose is to be a quick reference for logistics formulas and
principles to help you manage your supplies (both contraceptives and
other commodities) correctly and efficiently.
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UNICEF trucks water to the camps where people displaced by the conflict have temporarily settled. UNICEF also installed latrines, showers and water storage tanks in the camps and distributed family hygiene kits to protect children against waterborne
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diseases.
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Strengthening supply chains to meet the growing demand for family planning will require systems diagnostics, supply chain redesign or adjustments, strategically located storage and distribution systems, adequate staffing and training, and better inf
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ormation about inventory and financing.
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The aim of the operational framework is to ensure 1) accurate collection, handling, shipment and storage of specimens collected in countries implementing HIV drug resistance surveillance; and 2) the availability of quality-assured HIV genotyping lab
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oratory services producing comparable and reliable results at the national, regional and global levels.
This publication updates the WHO HIVResNet HIV drug resistance laboratory operational framework published in 2017 and reflects technical and strategic developments over the past three years.
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This document aims to support public health preparedness planning and response activities on the safe handling of bodies of deceased persons with suspected or confirmed COVID-19: at the site of death, during transport, storage and preparation before
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burial/cremation, and during burial/cremation.
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Health Care Facilities (HCFs) are primarily responsible for management of the healthcare waste generated within the facilities, including activities undertaken by them in the community. The health care facilities, while generating the waste are responsible for segregation, collection, in-house trans
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portation, pre-treatment of waste and storage of waste, before such waste is collected by Common Bio-medical Waste Treatment Facility(CBWTF) Operator. Thus, for proper management of the waste in the healthcare facilities the technical requirements of waste handling are needed to be understood and practiced by each category of the staff in accordance with the BMWM.
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