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Improving the global diagnosis and management of asthma in children

Lenney, W.; Bush, A.; Fitzgerald, D.A. et al. BMJ Journals (2018) CC

Asthma is the most common chronic condition in children worldwide. It affects daytime activities, sleep and school attendance and causes anxiety to parents, families and other carers. The quality of asthma diagnosis and management globally still needs substantial improvement. From infancy to the tee... more

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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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WHO manual for HIV drug resistance testing using dried blood spot specimens

World Health Organization WHO (2020) C_WHO

HIV-1 drug resistance (HIVDR) genotyping is an essential component of the WHO global HIVDR surveillance strategy. Plasma “gold standard” specimen type for HIVDR genotyping, but its use may not be feasible in rural, remote areas in low- and middle-income countries, since preparing and storing it ... more

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Botswana: Guidelines on Good Manufacturing Practices

Ministry of Health, Gabarone, Botswana (2009) C2

Drug Advisory Board

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Healthcare waste

USAID (2019) C1

Sector Environmental Guidelines, Full technical Update

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COVID-19 and Food Safety: Guidance for Food Businesses

World Health Organization WHO (2020) C_WHO

External Link

Novel vaccination approaches to prevent tuberculosis in children

J. A. Triccas, C. Counoupas Pneumonia; BioMed Central (2016) CC

Review Triccas and Counoupas Pneumonia (2016) 8:18; DOI 10.1186/s41479-016-0020-z

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Policy brief on tuberculosis-associated disability

World Health Organization WHO (2023) C_WHO

People affected by impairments and disabilities associated with TB are even more likely to belong to marginalized segments of society and are more likely to have their human rights unprotected. The challenges faced by people affected by TB include the consequences of impairment and disability associ... more

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Recommendacónes para o manejo da coinfeccáo TB-HIV em servicos de actencáo especializada a pessoas vivendo com HIV/AIDS

Ministério da saúde; TB HIV; Junitos pelo fin da Tuberculose (2013) C2

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Global Land Outlook Second Edition: Land Restoration for Recovery and Resilience

UN Convention to Combat Desertification (2022) CC

27 April 2022 Chronic land degradation: UN offers stark warnings and practical remedies in Global Land Outlook 2. GLO2 offers hundreds of examples from around the world that demonstrate the potential of land restoration. The way land resources – soil, water and biodiversity – are currently mi... more

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Profil Penanggulangan Krisis Kesehatan Kabupaten / Kota Rawan Bencana : Kabupaten Mamasa

Pusat Krisis Kesehatan Ministry of Health of Republic of Indonesia (2016) C1

Profile of health crisis response in potential areas of natural disaster in Indonesia : District of Mamasa

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The treatment of epilepsy in developing countries: where do we go from here?

Robert A. Scott, Samden D. Lhatoo & Josemir W.A.S. Sander WHO (2001) C_WHO

Bulletin of the World Health Organization, 2001, 79 (4)

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WHO implementation tool for pre-exposure prophylaxis of HIV infection - Module 9

World Health Organization (WHO) World Health Organization (WHO) (2017) C_WHO

Module 9 Strategic planning July 2017 Module 9: Strategic planning. As WHO recommends offering PrEP to people at substantial HIV risk, this module offers public health guidance for policy-makers on how to prioritize services, in order to reach those who could benefit most from PrEP, and in wh... more

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Africa, WASH, and the Millennium Development Goals: A Local Systems Case Study of How Senegal Achieved MDG Target 7c

McGahey, Christopher USAID (2017) C1

Nationally, Senegal met the MDG target for water supply access. It did this by engaging the public and private sectors to effectively invest and report on investments. It focused on larger population centers, less on remote regions of the country. Its achievements set the stage for more equitable an... more

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HOW TO CONDUCT MATERNAL DEATH REVIEWS (MDR)

De Brouwere V., Zinnen V., Delvaux T. (2013)

Guidelines and tools for Health Professionals

External Link

Instrumentos internacionales de Derechos Humanos

Naciones Unidas; Oficina del Alto Comisionado de las Naciones Unidas para los Derechos Humanos (OACNUDH), et al. (2006) C1

Convención sobre los Derechos de las Personas con Discapacidad, Protocolo Facultativo de la Convención sobre los Derechos de las Personas con Discapacidad

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Invisible Wounds. The impact of six years of war on the mental health of Syria’s children

Save the Children (2017) C1

“The children are psychologically crushed and tired. When we do activities like singing with them, they don’t respond at all. They don’t laugh like they would normally. They draw images of children being butchered in the war, or tanks, or the siege and the lack of food.” Teacher in the... more