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Integrating Clinical Research into Epidemic Response: The Ebola Experience

Gerald Keusch, Keith McAdam, Patricia Cuff, Michelle Mancher, and Emily R. Busta National Academies of Sciences, Engineering, and Medicine (2017) C1

The 2014–2015 Ebola epidemic in western Africa was the longest and most deadly Ebola epidemic in history, resulting in 28,616 cases and 11,310 deaths in Guinea, Liberia, and Sierra Leone. The Ebola virus has been known since 1976, when two separate outbreaks were identified in the Democratic Repub... more

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The social and cultural aspects of mental health in African societies

Mary Amuyunzu-Nyamongo Commonwealth Health Partnerships (2013) C2

The World Health Organization (WHO) defines mental health as ‘a state of well-being in which the individual realizes his or her own abilities, can cope with the normal stresses of life, can work productively and fruitfully, and is able to make a contribution to his or her community’. Mental illn... more

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Antimicrobial stewardship in a rural regional hospital – growing a positive culture

Juanid, E.; L. Jenkins, H. Swanepoel, et al. (2018) CC

S Afr Med J 2018;108(7):546-550. DOI:10.7196/SAMJ.2018.v108i7.13149 Antimicrobial stewardship programmes have been introduced worldwide in response to the rise in antimicrobial resistance. The World Health Organization has mandated each Member State to produce a plan to address this problem. We rep... more

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Global Competency-Based Fistula Surgery Training Manual

FIGO and Partners; UNFPA (2011)

Too few physicians are equipped with the knowledge and skills needed to repair genital fistulae and care for patients following surgery. Most procedures are performed in Africa and Asia by local physicians, with technical support from surgeons from developed countries where these fistulae are rarely... more

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Wits RHI’s Key responses to COVID-19

University of Witwatersrand (2020) C2

Wits Reproductive Health and HIV Institute (Wits RHI) is involved in an effort to curb the COVID-19 pandemic that is facing South Africa and the world at large. Prof. Helen Rees is a member of the team advising the Health Minister on COVID-19 (MAC). She is part of the Clinicians Group, the Research ... more

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The Corona Virus Disease 2019 (COVID-19) Strategic Response Plan for the WHO African Region February – December 2020 (Update 4 May 2020)

World Health Organization WHO (2020) C_WHO

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Variole du singe : Cours d'introduction aux contextes d'épidémies en Afrique

World Health Organization (WHO) (2020) C_WHO

La variole du singe est une maladie infectieuse émergente causée par un virus transmis par des animaux infectés, le plus souvent des rongeurs. Elle peut ensuite se propager d’une personne à l’autre, mais la transmission de personne à personne ne peut à elle seule entretenir une éclosion. ... more

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Monkeypox: Epidemiology, preparedness and response for African outbreak contexts

World Health Organization (WHO) (2021) C_WHO

Monkeypox is a viral zoonotic disease, caused by monkeypox virus, recognized as the most important orthopoxvirus infection after the eradication of smallpox. This course offers public health officers and health workers in-depth information to understand the epidemiology, modes of transmission, clin... more

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Variole du singe : Épidémiologie, préparation et réponse aux contextes d'épidémies en Afrique

World Health Organization (WHO) (2021) C_WHO

L’orthopoxvirose simienne, aussi connu sous les noms de variole du singe ou monkeypox, est une zoonose causée par l'orthopoxvirus simien et reconnue comme l'infection à orthopoxvirus la plus importante depuis l'éradication de la variole. Ce cours offre aux personnel de santé publique et aux a... more

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Monkeypox: Introductory course for African outbreak contexts -جُدري القردة: دورة تدريبية تمهيدية حول سياقات الفاشيات الإفريقية

World Health Organization (WHO) (2022) C_WHO

جُدري القردة مرضٌ معدٍ مستجدٌ، يسبِّبه فيروس ينتقل إلى البشر من الحيوانات المصابة، التي تكون من القوارض في أغلب الأحيان. ويمكن أن تنتشر العدوى به إلى أشخاص آخرين، إ�... more

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African Trypanosomiasis

Chelsea Marie, William A. Petri, Jr. (2022) C2

Human African trypanosomiasis is caused by Trypanosoma brucei gambiense in West and Central Africa and by T. brucei rhodesiense in East Africa; both species are endemic in Uganda. Trypanosoma brucei gambiense accounts for 98% of all cases of African trypanosomiasis, and T. brucei rhodesiense account... more

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New Drugs for Human African Trypanosomiasis: A Twenty First Century Success Story

Dickie, E.A.; Giordani, F.; Gould, M.K.; Mäser, P.; Burri, C.; Mottram, J.C.; Rao, S.P.S.; Barrett, M.P. MDPI Tropical Medicine and Infectious Disease (2020) CC2

The twentieth century ended with human African trypanosomiasis (HAT) epidemics raging across many parts of Africa. Resistance to existing drugs was emerging, and many programs aiming to contain the disease had ground to a halt, given previous success against HAT and the competing priorities associat... more

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The new WHO guideline for control and elimination of human schistosomiasis: implications for the Schistosomiasis Elimination Programme in Nigeria

Akinola Stephen Oluwole, Uwem Friday Ekpo, Obiageli Josephine Nebe et al. Infectious Diseases of Poverty (2022) CC

With some 134,073,166 people living in endemic communities at risk of infection, Nigeria is the most endemic country in Africa and requires preventive chemotherapy (PC) for a total of 26.3 million persons. The National Schistosomiasis Elimination Programme (NSCHEP), with the support of international... more

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WHO Eritrea 2022 Annual Report

World Health Organisation (WHO) (2023) C_WHO

During the year 2022, COVID-19 continued to be a significant challenge in Eritrea as in many other countries across the world. As COVID-19 devastated communities around the world, WHO worked with the MoH to strengthen the National and Sub-National health systems in order to meet community needs and ... more

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The elimination of human African trypanosomiasis: Achievements in relation to WHO road map targets for 2020

Franco JR, Cecchi G, Paone M, Diarra A, Grout L, et al. (2022) CC

Human African trypanosomiasis (HAT) is a lethal neglected tropical disease (NTD) transmitted by the bite of infected tsetse flies. The disease is also known as “sleeping sickness”. During the 20th century it caused enormous suffering in the endemic areas in sub-Saharan Africa. HAT transmission l... more

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African Regional Convening to Support Parents and Caregivers

World Health Organisation (WHO) (2023) C_WHO

The African Regional Convening of the Global Initiative to Support Parents (GISP) stimulated the interest or engagement of almost 1500 individuals from 742 unique organizations in the fields of health, education, social welfare, women’s affairs, early childhood, water and sanitation, mental health... more

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WHO South Sudan Annual Report 2022

World Health Organisation (WHO) (2023) C_WHO

A lot has happened this year. While we continued to tackle the COVID-19 pandemic, we were hit by disease outbreaks and humanitarian crises. Yet, despite these challenges, we marched on, resolute in resolving critical health systems issues to increase access to quality healthcare services. To furth... more

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Annual Report of the WHO Country Office in Zimbabwe, 2022

World Health Organisation (WHO) (2023) C_WHO

This report highlights the work of the World Health Organization (WHO) in Zimbabwe towards contributing to the triple billion targets in the context of the Sustainable Development Goals (SDGs

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The Abuja Declaration: Ten Years On

World Health Organization (WHO) World Health Organization (WHO) (2010) CC

Follow up to the so called Abuja Declaration ten years later: In April 2001, heads of state of African Union countries met and pledged to set a target of allocating at least 15% of their annual budget to improve the health sector. At the same time, they urged donor countries to "fulfil the yet to be... more

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Management of a cholera epidemic - Practical guide for doctors, nurses, laboratory technicians, medical auxiliaries, water and sanitation specialists and logisticians
recommended

Médecins Sans Frontières MFS (2023) CC

Cholera is a transmissible diarrhoeal infection caused by Vibrio cholerae. Endemic and/or epidemic in over 40 countries (mainly in Africa and Asia), cholera continues to be a major global public health issue. The World Health Organization (WHO) estimates that the number of cases reported worldwid...e represents in reality only 5 to 10% of actual cases. This guide is intended for medical and non-medical staff responding to a cholera outbreak. It attempts to provide concrete answers to the questions and problems faced by staff, based on the recommendations of reference organisations, such as WHO and UNICEF, as well as Médecins Sans Frontières’ experience in the field. It is divided into 8 chapters. Chapter 1, Cholera overview, outlines the epidemiological and clinical features of cholera. Chapter 2, Outbreak investigation, explains the method and stages of a field investigation, from the alert to implementation of initial activities. Chapter 3, Cholera control measures, details measures and tools to prevent and/or control cholera transmission and mortality in populations affected, or at risk of being affected, by an epidemic (curative care, prevention means and health promotion activities). Chapter 4, Strategies for epidemic response, addresses the roll-out strategies of the measures described in Chapter 3 which depend on context (e.g. urban, rural, endemic, non-endemic setting, etc.), resources and particular constraints. Chapter 5, Cholera case management, details the different stages of cholera treatment, from diagnosis through to cure. Chapter 6, Setting up cholera treatment facilities, focuses on the installation of treatment facilities that vary in size and complexity according to operational requirements (treatment centres and units and oral rehydration points). Chapter 7, Organisation of cholera treatment facilities, describes the organisation of these specialized facilities in terms of human resources, supply, water, hygiene and sanitation, etc. Chapter 8, Monitoring and evaluation, presents the key data to be collected and analysed during an epidemic to facilitate a tailored response and evaluate its quality and effectiveness. The guide includes various practical tools in the appendices to facilitate activities (e.g. water quality tests, job descriptions, documents, etc.). Moreover, the toolbox also contains additional tools in editable formats (individual patient file, cholera case register, pictograms). Despite all efforts, it is possible that certain errors may have been overlooked in this guide. Please inform the authors of any errors detected. To ensure that this guide continues to evolve while remaining adapted to field realities, please send any comments or suggestions. more

Management of a cholera epidemic - Practical guide for doctors, nurses, laboratory technicians, medical auxiliaries, water and sanitation specialists and logisticians recommended

Management of a cholera epidemic - Practical guide for doctors, nurses, laboratory technicians, medical auxiliaries, water and sanitation specialists and logisticians
recommended