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European Union - Overview

Drug War Facts; Common Sense for Drug Policy (2019) C2
Accessed: 28.03.2019
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Medication in Prison Associated with Reductions in Fatal Opioid Overdoses After Release

National Institute on Drug Abuse (2018) C2
Science Spotlight February 14, 2018
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Trends in World seizures: 2000 - 2010

United Nations Office on Drugs and Crime (2019) C2
Accessed: 14.03.2019
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Improving access to testing for Chagas disease in Colombia

Caicedo Díaz, RA,; Forsyth, C.; Bernal, OA; et al. Drugs for Neglected Diseases initiative DNDi (2019) CC
This is a summary of the following peer-reviewed, scientific article: Comparative Evaluation of Immunoassays to Improve Access to Diagnosis for Chagas Disease in Colombia.
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Chagas Clinical Research Platform

Drugs for Neglected Diseases Initiative DNDi Latin America (2022) CC
To support its R&D activities on Chagas disease, DNDi launched the Chagas Clinical Research Platform (CCRP). The platform brings together partners, experts, and stakeholders to provide support for evaluation and development of new treatments for Chagas disease. The patient-centred platform aims to f... more
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Chagas disease factsheet

Drugs for Neglected Diseases initiative DNDi - Latin America (2019) CC
Chagas is a parasitic disease that affects over 6 million people in the world. As the disease typically remains asymptomatic for years, new cases often go unnoticed and unreported, and most people with the disease are unaware of their condition. Less than 10% of people affected are diagnosed and... more
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Human African Trypanosomiasis (HAT) - Sleeping Sickness

Drugs for Neglected Diseases initiative DNDi (2008) C2
At the forefront of DNDi’s efforts to develop new treatments is the need to understand the realities and treatment needs of patients and health care staff in the field. The ultimate goal for human African trypanosomiasis (HAT) is a truly simplified treatment which can be orally administered, impl... more
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Fexinidazole for T.b. rhodesiense

Drugs for Neglected Diseases initiative DNDi (2021) C1
DNDi’s long-term goal for sleeping sickness, also known as human African trypanosomiasis (HAT), is to develop and register two new drugs that are effective against both Stage 1 and Stage 2 of the disease and both subspecies of the parasite, T.b. gambiense and T.b. rhodesiense. T.b. rhodesiense is ... more
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Fexinidazole for T.b. gambiense (Sleeping Sickness)

Drugs for Neglected Diseases initiative DNDi (2022) C2
DNDi is now striving to make fexinidazole available to the majority of people who have T.b. gambiense sleeping sickness. We are supporting a three-year access and pharmacovigilance study that began in 2020 and have so far carried out in-country training of relevant staff in 250 hospitals and... more
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Enfermedad de Chagas ESP

Drugs for Neglected Diseases initiative DNDi - Latin America (2019) CC
La enfermedad de Chagas es parasitaria y afecta a más de 6 millones de personas en el mundo. Como normalmente es asintomática durante años, los nuevos casos suelen no detectarse ni reportarse y la mayoría de las personas con la enfermedad no tiene conciencia de su condición. Se diagnostica ... more
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Full prescribing information Fexinidazole tablets, for oral use

Drugs for Neglected Diseases initiative DNDi (2021) C1
Full Perscribing information on Fexinidazole Tablet for oral use INDICATIONS AND USAGE Fexinidazole Tablets are indicated for the treatment of both the first-stage (hemolymphatic) and second-stage (meningoencephalitic) human African trypanosomiasis (HAT) due to Trypanosoma brucei gambiense in pati... more
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New hope for leishmaniasis

Drugs for Neglected Diseases initiative DNDi (2022) CC
Leishmaniasis is a climate-sensitive disease. Changes in temperature, rainfall, and humidity can have strong impacts on the sandfly vector, altering their distribution and influencing their survival and population sizes. Increased temperatures shorten vector development time, reduce Leishmania p... more
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Una Nueva Esperanza Para Pacientes Con Leishmaniasis

Drugs for Neglected Diseases initiative DNDi (2022) CC
La leishmaniasis es una enfermedad tropical desatendida sensible al clima, trasmitida por la picadura de insectos flebótomos y se calcula que amenaza a mil millones de personas en todo el mundo. Esta enfermedad altamente compleja se presenta de varias formas clínicas, causadas por 20 especies ... more
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Mycetoma: New hope for neglected patients?

Drugs for Neglected Diseases initiative DNDi (2019) CC
Mycetoma is a slow-growing bacterial or fungal infection, most often of the foot, that may spread to other parts of the body and can cause severe deformity. It is a debilitating disease that most often affects poor people in rural areas with limited access to health care.
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Visceral leishmaniasis

Drugs for Neglected Diseases initiative DNDi (2023) CC
Visceral leishmaniasis, the most severe form of leishmaniasis also known as kala-azar, is a life-threatening disease caused by Leishmania parasites which are transmitted by female sandflies. Visceral leishmaniasis causes fever, weight loss, spleen and liver enlargement, and, if not treated, death. P... more
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Webinar: Knowledge gaps and challenges in managing patients suffering from cutaneous leishmaniasis

Drugs for Neglected Diseases initiative DNDi (2021) CC
Cutaneous leishmaniasis is a painful disease that exerts a serious toll on societies around the world that are afflicted by it. Although not life-threatening, the skin ulcers and scars it causes can lead to isolation and psychosocial pathologies due to social stigma, and its occurrence is often asso... more
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Towards new generation treatments for leishmaniasis

Drugs for Neglected Diseases initiative DNDi (2019) CC
1 billion people are at risk of infection with leishmaniasis, a neglected disease strongly linked to poverty. There’s no single, simple cure: current treatments are complex and need to be adapted to the form of the disease and geographical region.
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The Mark of Neglect: Cutaneous Leishmaniasis

Drugs for Neglected Diseases initiative DNDi (2014) CC
Leishmaniasis is among the most neglected diseases. The most common form is cutaneous leishmaniasis that forms lesions on the skin. The only treatment available for cutaneous leishmaniasis is highly toxic. In some cases, patients have died because of the treatment, even though cutaneous leishmania... more
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From neglect to hope: Voices of leishmaniasis

Drugs for neglected diseases initiative DNDi (2023) C2
Website last accessed on 14.04.2023 Health workers Luke (Kenya), Juliana (Colombia), and Shishu (India) share the same hope for their patients with leishmaniasis: simple, oral treatments. For the first time ever, it seems leishmaniasis research is moving from neglect to a sense of hope.
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LEAP Platform | DNDi

Drugs for neglected diseases initiative DNDi (2023) C2
Website last accessed on 22.05.2023 The LEAP platform aims to strengthen clinical research capacity, which is lacking in part due to the remoteness and geographic spread of the patients, most of whom live in the most impoverished regions of Africa.