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1
Breakthrough innovations have come to light that have proved to be more than 95% effective in preventing HIV infection with injections just twice a year. Once a year might even be possible. They could also be key for 40 million people living with HIV around the world who need better options for trea
...
tment. It’s not a cure or a vaccine, but it could be a game-changer if made accessible to all who could benefit.
more
Addressing comorbidities and risk factors for tuberculosis (TB) is a crucial component of the World Health Organization (WHO)’s End TB Strategy. This WHO operational handbook on tuberculosis. Module 6: tuberculosis and comorbidities aims to support countries in scaling up people-centred care, base
...
d on the latest WHO recommendations on TB and key comorbidities, and drawing upon additional evidence, best practices and inputs from various experts and stakeholders obtained during WHO processes. It is intended for use by people working in ministries of health, particularly TB programmes and the relevant departments or programmes responsible for comorbidities and health-related risk factors for TB such as HIV, diabetes, undernutrition, substance use, and tobacco use, as well as programmes addressing mental health and lung health. This operational handbook is a living document and will include a separate section for each of the key TB comorbidities or health-related risk factors. The third edition includes guidance for HIV-associated TB, mental health conditions and diabetes, which are three conditions strongly associated with TB and which result in higher mortality, poorer TB treatment outcomes and negatively impact health-related quality of life. The operational handbook aims to facilitate early detection, proper assessment and adequate management of people affected by TB and comorbidities. Full implementation of this guidance is expected to have a significant impact on TB treatment outcomes and health-related quality of life for people affected by TB.
more
This template dossier complements and should be used after fulfilling the criteria and preconditions specified in the Process of validation of elimination of kala-azar as a public health problem in South-East Asia. The national kala-azar programme should be in the consolidation phase of elimination;
...
that is, the annual incidence of kala-azar in the implementation unit is maintained below 1 case (new plus relapse) per 10 000 population for a minimum of 3 consecutive years.
The template is designed to help national kala-azar elimination programmes prepare a dossier documenting the essential evidence supporting the request to the World Health Organization (WHO) to validate the status of kala-azar elimination as a public health problem in their country. The information presented in this document will help independent assessors understand the national programme’s specific context, achievements and relevant epidemiological data.
The dossier should be organized according to the following sections:
- Description of the country context and health system capabilities
- Historical data and delineation of endemic areas
- Surveillance and elimination activities
- Epidemiological data
- Vector control strategy and activities
- Post-validation surveillance plan
Once the dossier is prepared, it should be examined and duly endorsed by the National Task Force on kala-azar elimination and/or neglected tropical diseases, or a similar body, before submission to WHO.
more
- The goal of diagnostic testing for Ebola and Marburg virus diseases is to identify cases to provide timely and appropriate care and to stop disease transmission.
- All individuals meeting the case definition for Ebola or Marburg virus diseases should be tested.
- The recommended sample type
...
for testing for orthoebolaviruses and orthomarburgviruses is whole blood or plasma for living patients, and oral swab for deceased individuals.
- Laboratory confirmation of Orthoebolavirus and Orthomarburgvirus infections and further species identification should be done using nucleic acid amplification testing (NAAT).
- If a suspected case tests negative (living patient) and the blood was drawn less than 72 hours after symptom onset, a second test should be performed with blood drawn more than 72 hours after symptom onset.
- All manipulations in laboratory settings of samples originating from suspected, probable or confirmed cases of Ebola and Marburg virus diseases should be conducted with appropriate biosafety measures according to a risk-based approach.
- Whole or partial genome sequencing can be used to characterize viruses and complement epidemiologic investigations.
- Member States are strongly encouraged to share genetic sequence data (GSD) in publicly accessible databases.
- Member States are required to immediately notify the World Health Organization (WHO) under the International Health Regulations (IHR) 2005 of positive laboratory results.
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The effective vaccine management (EVM) workshop, jointly organized by WHO and UNICEF, was attended by participants from 13 countries, who reviewed the various EVM benchmarks, identified the gaps in policies, guidelines, SOPs and job aids, and developed respective country action plans to fill these g
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aps. This meeting report outlines the proceedings and outcomes of the workshop conducted in Bangkok, Thailand, in December 2024
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La vidéo "Choléra - Questions & Réponses" de l'Organisation Mondiale de la Santé (OMS) explique les aspects essentiels du choléra, une maladie diarrhéique aiguë causée par l'ingestion d'eau ou d'aliments contaminés par la bactérie Vibrio cholerae. Elle met en avant les principaux symptôme
...
s, notamment une diarrhée aqueuse sévère, des vomissements et une déshydratation rapide, pouvant être mortelle sans traitement adéquat. La transmission se fait principalement par l’eau insalubre et les mauvaises conditions sanitaires. Pour prévenir la maladie, il est essentiel d'avoir accès à de l'eau potable, d'améliorer l'hygiène et l'assainissement, et d'utiliser la vaccination dans les zones à haut risque. En cas d'infection, la réhydratation orale ou intraveineuse est le traitement principal, tandis que les antibiotiques sont parfois administrés dans les cas graves. La vidéo insiste sur l'importance d'une intervention rapide et de mesures préventives pour limiter la propagation du choléra et protéger les populations à risque.
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The video "Cholera - Questions & Answers" by the World Health Organization (WHO) explains the essential aspects of cholera, an acute diarrheal disease caused by ingesting water or food contaminated with the Vibrio cholerae bacterium. It highlights the main symptoms, including severe watery diarrhea,
...
vomiting, and rapid dehydration, which can be fatal without proper treatment. Transmission occurs primarily through unsafe water and poor sanitation conditions. To prevent the disease, it is crucial to have access to clean drinking water, improve hygiene and sanitation, and use vaccination in high-risk areas. In case of infection, oral or intravenous rehydration is the primary treatment, while antibiotics are sometimes administered in severe cases. The video emphasizes the importance of rapid intervention and preventive measures to limit the spread of cholera and protect at-risk populations.
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MSF often responds to outbreaks of cholera in the countries we work. But how do we set up our cholera treatment centres to ensure our patients get the best care possible - and that the disease doesn't spread? Learn more about the layout and activities of an MSF cholera treatment centre in this inter
...
active guide.
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The World Health Organization (WHO) African Region website provides comprehensive information on cholera outbreaks across the continent. In 2024, 14 countries, including the Democratic Republic of the Congo, Ethiopia, and Nigeria, experienced significant outbreaks, with these three nations categoriz
...
ed as being in acute crisis.
The site offers access to Monthly Regional Cholera Bulletins, such as the May 2024 edition, which details the status of outbreaks, affected countries, and response measures.
Additionally, the website emphasizes the importance of coordinated responses to cholera outbreaks, highlighting efforts to enhance surveillance, provide medical supplies, and implement vaccination campaigns in high-risk areas.
Overall, the WHO African Region's cholera page serves as a vital resource for understanding the scope of cholera outbreaks and the ongoing initiatives to control and prevent the disease across the continent.
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This publication discusses official development assistance (ODA) provided by the USA with a focus on health, HIV/AIDS, tuberculosis and malaria. It also reflects upon ODA by the USA in comparison to other donors and funding targets.
Diese Veröffentlichung befasst sich mit der öffentlichen Entwicklungshilfe (Official Development Assistance, ODA) der USA mit Schwerpunkt auf den Bereichen Gesundheit, HIV/AIDS, Tuberkulose und Malaria. Außerdem wird die ODA der USA im Vergleich zu anderen Gebern und Finanzierungszielen betrachte
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t.
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Multi-country outbreak of cholera External Situation Report # 23, published 20 February 2025
The document provides an overview of malaria in the Americas, describing its transmission, symptoms, vulnerable populations, and regional trends, while highlighting prevention strategies and the efforts of PAHO/WHO and member states to eliminate the disease by 2020.
The CDC webpage on the clinical features of malaria outlines the disease's presentation, categorizing it into uncomplicated and severe forms, and emphasizes that prompt and accurate diagnosis and treatment can lead to a cure.
El sitio web de la OMS titulado "Malaria" ofrece una visión completa de la malaria, una enfermedad potencialmente mortal causada por parásitos del género Plasmodium y transmitida principalmente por picaduras de mosquitos en países tropicales. Proporciona información sobre los síntomas, los gru
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pos de riesgo, las medidas de prevención y las opciones de tratamiento. El sitio también presenta estadísticas recientes: en 2023, se estimaron 263 millones de casos de malaria y 597,000 muertes en 83 países, siendo la región africana la más afectada, con el 94 % de los casos y el 95 % de las muertes. Los niños menores de cinco años representaron aproximadamente el 76 % de las muertes en esta región.
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The WHO website titled "Malaria" provides a comprehensive overview of malaria, a potentially fatal disease caused by Plasmodium parasites and primarily transmitted through mosquito bites in tropical countries. It offers information on symptoms, at-risk groups, preventive measures, and treatment opti
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ons. The site also presents recent statistics: in 2023, an estimated 263 million malaria cases and 597,000 deaths occurred in 83 countries, with the African region being the most affected—accounting for 94% of cases and 95% of deaths. Children under the age of five made up approximately 76% of the deaths in this region.
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The WHO website titled "Malaria" provides a comprehensive overview of malaria, a potentially fatal disease caused by Plasmodium parasites and primarily transmitted through mosquito bites in tropical countries. It offers information on symptoms, at-risk groups, preventive measures, and treatment opti
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ons. The site also presents recent statistics: in 2023, an estimated 263 million malaria cases and 597,000 deaths occurred in 83 countries, with the African region being the most affected—accounting for 94% of cases and 95% of deaths. Children under the age of five made up approximately 76% of the deaths in this region.
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L’article du Manuel MSD en français sur le paludisme offre un aperçu détaillé de cette maladie parasitaire grave causée par des protozoaires du genre Plasmodium, transmis par les piqûres de moustiques Anopheles. Il décrit les différentes espèces responsables, les mécanismes d’infection
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, les symptômes cliniques comme la fièvre et l’anémie, ainsi que les méthodes de diagnostic et les options thérapeutiques, notamment les traitements antipaludiques.
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La page du Manuel MSD Professionnel consacrée au paludisme présente une synthèse complète de cette maladie parasitaire grave causée par des protozoaires du genre Plasmodium, transmis par les piqûres de moustiques Anopheles. Elle décrit les différentes espèces responsables, les cycles de vie
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du parasite, les signes cliniques typiques (comme la fièvre cyclique), les complications possibles, ainsi que les méthodes de diagnostic et les traitements antipaludiques disponibles. Le contenu s’adresse aux professionnels de santé et met l’accent sur la reconnaissance rapide, la prise en charge adaptée et la prévention du paludisme, notamment chez les voyageurs et les populations à risque.
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La page « Paludisme » du Centre de collaboration nationale des maladies infectieuses (CCNMI) offre une synthèse complète sur cette maladie parasitaire transmise par les moustiques Anopheles. Elle aborde les causes, les symptômes similaires à ceux de la grippe, les complications possibles,
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ainsi que les méthodes de diagnostic et les options thérapeutiques. De plus, elle traite de la déclaration obligatoire des cas au Canada et des mesures de surveillance en place. Cette ressource s'adresse aux professionnels de la santé publique canadienne, en fournissant des informations essentielles pour la gestion et la prévention du paludisme.
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