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Publication Years
3038
5098
755
45
6
1
Category
3172
891
472
429
321
257
124
3
Toolboxes
1101
886
565
530
423
339
307
306
227
175
170
142
140
139
131
122
104
99
87
65
50
49
47
36
34
1
Научная справка
24 апреля 2020 г.
При инфицировании в естественных условиях выработка иммунитета к патогенному микроорганизму проходит в несколько этапов и заним
...
ет от 1 до 2 недель. При вирусной инфекции врожденный иммунитет обеспечивает немедленную реакцию организма, которая заключается в активации неспецифического иммунного ответа, приводящего к замедлению инфекционного процесса макрофагами, нейтрофилами и дендритными клетками, и которая в ряде случаев обусловливает бессимптомное течение инфекции. Затем происходит активация адаптивного иммунного ответа, при котором в организме начинается выработка специфических антител, способных к связыванию с вирусными частицами. Данные антитела являются белками и носят название иммуноглобулинов. Кроме того, в организме образуются Т-клетки, способные распознавать и уничтожать другие клетки, пораженные вирусом. Это звено иммунитета носит название клеточного. Функционирование нескольких звеньев иммунитета при адаптивном ответе может способствовать элиминации вируса из организма, а при достаточной активности реакции – препятствовать переходу заболевания в тяжелую форму и повторному заражению той же инфекцией. Количественной мерой данного процесса является уровень антител в крови.
more
Patients with suspected coronavirus disease 2019 (COVID-19) can infect others at any time, including during transfer and transport. COVID-19 is a new infectious disease that requires contact and droplet precautions; lapses in infection prevention and control (IPC) can easily happen at vulnerable mom
...
ents such as during transfer. This guide aims to identify key steps to prepare the community and health system response to ensure IPC is maintained during transfer and transport. This guide is intended for personnel involved in coordinating and performing transfer and transport of patients with suspected COVID-19 requiring hospital care.
more
People with underlying noncommunicable diseases (NCDs) such as hypertension, diabetes, cardiovascular disease, chronic respiratory disease and cancer have a high risk for developing severe and even fatal COVID-19. It is important for them to strictly follow basic protective measures and make sure th
...
eir chronic diseases are well managed. However, pandemics cripple health systems and compromise provision routine medical care. This technical note gives general guidance to people living with NCDs, their caregivers and family members, the public, health programme managers and health-care workers on how to reduce risks of a COVID-19 infection and maintain care for people living with NCDs during the outbreak.
more
This topic last updated: Apr 28, 2020.
The content on the UpToDate website is not intended nor recommended as a substitute for medical advice, diagnosis, or treatment. Always seek the advice of your own physician or other qualified health care professional regarding any medical questions or condi
...
tions.
View in: English, Italian, French, German, Japanese, Brazilian Portuguese, Video in Spanish
more
This topic last updated: Apr 28, 2020.
The content on the UpToDate website is not intended nor recommended as a substitute for medical advice, diagnosis, or treatment. Always seek the advice of your own physician or other qualified health care professional regarding any medical questions or conditi
...
ons.
View in: English, Italian, French, German, Japanese, Brazilian Portuguese, Video in Spanish
more
Accessed: 02.05.2020
Coronaviruses are a large family of viruses that are known to cause illness ranging from the common cold to more severe diseases such as Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS).
Emerg Infect Dis. 2020 Jul [date cited]. https://doi.org/10.3201/eid2607.200915
Infection control instructions call for use of alcohol-based hand rub solutions to inactivate severe acute respiratory syndrome coronavirus 2. We determined the virucidal activity of World Health Organization–recommen
...
ded hand rub formulations, at full strength and multiple dilutions, and of the active ingredients. All disinfectants demonstrated efficient virus inactivation.
more
Presently, there is no evidence that the virus responsible for the current COVID-19 pandemic is carried by domestic food-producing animals, such as chickens, ducks, other poultry, pigs, cattle, camels, horses, sheep, goats, rabbits, guinea pigs or fish. While live animals can be a source of pathogen
...
s, all types of food can potentially be contaminated through contact with contaminated equipment, surfaces or environments. Proper cleaning and the prevention of cross-contamination are critical in the control of foodborne illnesses. The application of sound principles of environmental sanitation, personal hygiene and established food safety practices will reduce the likelihood that harmful pathogens will threaten the safety of the food supply, regardless of whether the food is sourced from intensive agriculture, small stakeholders or wildlife.
more
Basic psychosocial support skills are at the core of any Mental Health and PsychosocialSupport (MHPSS) intervention. Such skills are also indispensable for many others involvedin the COVID-19 response, whether they identify as an MHPSS provider or not. Thus, this guide is meant for all COVID-19 resp
...
onders.
It is available in different languages: English, French, Spanish, Arabic, Amharic, Greek, Chinese, Bahasa Indonesia, Russian
more
As of 15 May 2020, more than 4 million confirmed cases of COVID-19, including more than 285,000 deaths have been reported to WHO. The risk of severe disease and death has been highest in older people and in persons with underlying noncommunicable diseases (NCDs), such as hypertension, cardiac diseas
...
e, chronic lung disease and cancer.
more
This guidance note identifies strategic action for policy-makers and managers at the national, subnational and facility level to address these different challenges.
This document provides brief information answering common questions regarding COVID-19 diagnostic tests and how to prioritize them to the patients most in need.
This document offers guidance to Member States in the African region on the key steps used to conduct contact tracing related to the COVID-19 response. It is to be used by national and local health authorities in the implementation of tracing of contacts of probable and confirmed COVID-19 cases.
While the COVID-19 pandemic threatens all members of society, persons with disabilities are disproportionately impacted due to attitudinal, environmental and institutional barriers that are reproduced in the COVID-19 response.
This technical brief was developed by the UNFPA Global Ageing Network to complement the UN Department of Economic and Social Affairs' (UN DESA) Issue Brief: Older Persons and COVID-19, which emphasized the humanitarian imperative of addressing older persons' specific needs within preparedness and re
...
sponse to the COVID-19 pandemic.
more
Supporting the continuity of health and nutrition services in the context of COVID-19 in refugee settings
recommended
The 2014–2015 Ebola outbreak was catastrophic in West Africa but the indirect impact of increasing the mortality rates of other conditions was also substantial. The increased number of deaths caused by malaria, HIV/AIDS, and tuberculosis attributable to health system failures exceeded deaths from
...
Ebola.
With a relatively limited COVID-19 caseload, health systems may have the capacity to maintain routine service delivery in addition to managing COVID-19 cases. When caseloads are high, and/or health workers are directly affected, strategic adaptations are required to ensure that increasingly limited resources provide maximum benefit for the refugees and surrounding host population. The following are key considerations for UNHCR operations on prioritized health care services in the event of a COVID-19 outbreak. These are based on WHO Guidance for Maintaining Essential Health Services and UNHCR guidance for operations and where relevant operation or site level outbreak preparedness and response plans.
more
Throughout the gestational period, it is important for obstetric health care facilities to strengthen health counselling, screening, and follow-ups for pregnant women, while incorporating screening, hand hygiene practice, good respiratory etiquette and infection prevention control precautions. These
...
screening procedures will help determine individualised precautions necessary, such as the wearing of face masks during consultations.
more
Nested case-control study of health workers exposed to confirmed COVID-19 patients.
Similar objectives to the cohort study but case-control studies may be cheaper and provide robust evidence to characterize and assess the risk factors for SARS-CoV-2 infection in health workers exposed to COVID-19 p
...
atients.
Health workers with confirmed COVID-19 will be recruited as cases and other health workers in the same health care setting without infection will be recruited as controls (incidence density sampling).
Secondary objectives are similar to the cohort study.
more
A list of some of the many free documents and websites that can add to the information in the papers published in this issue of SSMJ. Many are regularly updated. Let us know of other resources relevant to those working in and with South Sudan.
This document provides guidance to African Union Member States on key mental health and psychosocial support (MHPSS) considerations in relation to the coronavirus disease 2019 (COVID-19) pandemic. It contains useful guidance on MHPSS for the community, healthcare workers, caregivers of vulnerable po
...
pulations and people in quarantine, isolation or treatment centers(1)
(2). This guidance aims to provide practical steps to reduce stress, anxiety, stigma and psychological disorders associated with COVID-19 and improve overall mental health and well being. This guidance can be used for planning purposes by policy makers and Ministries of
health and institutions coordinating emergency response to COVID-19 response by Member States. It can also be disseminated to stakeholders.
more
