10 May 2021. Manufactureres:
SK Bioscience Co. Ltd. [COVID-19 Vaccine (ChAdOx1-S [recombinant])]
Serum Institute of India Pvt. Ltd. [COVISHIELD™, ChAdOx1 nCoV-19 Corona Virus Vaccine (Recombinant)]
The ChAdOx1-S/nCoV-19 [recombinant] vaccine is a replication-deficient adenoviral vecto...r vaccine against coronavirus disease 2019 (COVID-19). The vaccine expresses the SARS-CoV-2 spike protein gene, which instructs the host cells to produce the protein of the S-antigen unique to SARS-CoV-2, allowing the body to generate an immune response and to retain that information in memory immune cells. Efficacy shown in clinical trials in participants who received the full series of vaccine (2 doses) irrespective of interval between the doses was 63.1%, based on a median follow-up of 80 days, but tended to be higher when this interval was longer. The data reviewed at this time support the conclusion that the known and potential benefits of ChAdOx1-S/nCoV-19 [recombinant] vaccine outweigh the known and potential risks.
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13 May 2021
To avoid a reversal of progress from the adverse impacts of the COVID-19 pandemic, new knowledge and lessons from successful programmatic innovations are urgently needed to improve TB prevention and care. Experience can provide evidence for innovative approaches and strategies to mainta...in and scale up high-quality TB services. WHO therefore called for case studies on programmatic innovations that address emerging challenges in TB prevention and care during the pandemic in order to collect and disseminate the findings to the TB community. Between November 2020 and February 2021, a total of 23 case studies relevant to the call were accepted from 19 countries in the six regions of WHO. The lessons learnt from these country activities to ensure the continuity of essential services like TB care in the face of the crippling crisis may also inform strategies for minimizing the impact of future emerging pathogens on health services.
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Mit dem One Health Ansatz für gesunde Menschen, gesunde Tiere und eine gesunde Umwelt weltweit. Briefing paper.
Der One Health Ansatz nimmt das Zusammenspiel der Gesundheit von Mensch, Tier und Umwelt in
den Blick. Der Ansatz betont den Mehrwert einer trans-, multi- und interdisziplinären Zusamm...enarbeit zu den verschiedenen Themenbereichen. Ein multi-dimensionaler One Health Ansatz hat in den letzten Jahren zunehmend an Bedeutung gewonnen und wird nun von verschiedenen Akteuren als Ansatz zur Prävention und Reaktion auf zukünftige Pandemien gesehen
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Many critical questions remain about the effectiveness of COVID-19 vaccines in real-world settings. These questions can only be answered in post-introduction vaccine effectiveness studies.This guidance document outlines an approach to leverage existing surveillance systems for Severe Acute Respirato...ry Infection (SARI) to estimate COVID-19 vaccine effectiveness (VE) in preventing SARI associated with laboratory-confirmed SARS-CoV-2 using existing SARI surveillance systems. The approach uses the test-negative design to evaluate VE; cases are SARI patients who tested positive for SARS-CoV-2, and controls are SARI patients who tested negative for SARS-CoV-2.
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The report presents the latest data on more than 50 health-related Sustainable Development Goal and "triple billion" target indicators. The 2021 edition includes preliminary estimates for global excess deaths attributable to COVID-19 for 2020 and the state of global and regional health trends from 2...000-2019. It also focuses on persistent health inequalities and data gaps that have been accentuated by the pandemic, with a call to urgently invest in health information systems to ensure the world is better prepared with better data.
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Module appartenant à la série d’évaluations des capacités des services de santé dans le cadre de la pandémie de COVID-19: orientations provisoires, 12 mai 2021. L'outil d'évaluation de la continuité des services de santé essentiels : Facility Assessment Tool peut être utilisé par les pa...ys pour évaluer rapidement la capacité des établissements de santé à maintenir la prestation des services de santé essentiels pendant la pandémie de COVID-19. Il peut aider à alerter les autorités et les autres parties prenantes sur les points où la prestation et l'utilisation des services peuvent nécessiter des modifications et/ou des investissements. Cet outil d'évaluation couvre les aspects suivants des services de santé essentiels :
le personnel de santé (effectifs, absences, infections au COVID-19, gestion du personnel de santé, formation et soutien) ;
gestion financière et obstacles ;
prestation et utilisation des services (fermetures d'établissements, changements dans la prestation des services, campagnes de communication communautaires, changements dans l'utilisation des services et stratégies de rattrapage) ;
capacités en matière de prévention des infections (protocoles, mesures de sécurité, directives et disponibilité d'équipements de protection individuelle (EPI) pour le personnel) ;
la disponibilité des thérapeutiques, des diagnostics et des fournitures, et la disponibilité des vaccins ; et
la fourniture de services de soins primaires COVID-19.
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módulo del conjunto de evaluaciones de la capacidad de los servicios de salud en el contexto de la pandemia de COVID-19: orientaciones provisionales, 12 de mayo de 2021; La herramienta de evaluación de la continuidad de los servicios sanitarios esenciales: Herramienta de evaluación de instalacion...es puede ser utilizada por los países para evaluar rápidamente la capacidad de los centros de salud para mantener la prestación de servicios sanitarios esenciales durante la pandemia de COVID-19. Puede ayudar a alertar a las autoridades y a otras partes interesadas sobre los casos en que la prestación y utilización de los servicios puede requerir modificaciones y/o inversiones. Esta herramienta de evaluación abarca los siguientes aspectos de los servicios sanitarios esenciales
personal sanitario (número, ausencias, infecciones por COVID-19, gestión del personal sanitario, formación y apoyo)
gestión financiera y obstáculos;
prestación y utilización de los servicios (cierre de centros, cambios en la prestación de servicios, campañas de comunicación con la comunidad, cambios en la utilización de los servicios y estrategias de recuperación);
capacidades de CIP (protocolos, medidas de seguridad, directrices y disponibilidad de equipos de protección personal (EPP) para el personal)
la disponibilidad de terapias, diagnósticos y suministros, y la disponibilidad de vacunas; y
la prestación de servicios de atención primaria COVID-19.
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Available in Russian
A detailed overview is provided of the implementation of alcohol policies described in the 10 action areas of the European Action Plan to Reduce the Harmful Use of Alcohol 2012–2020 (EAPA), including the current status of implementation of the five action areas of the WHO-led... SAFER initiative:
Strengthen restrictions on alcohol availability;
Advance and enforce drink–driving countermeasures;
Facilitate access to screening, brief interventions and treatment;
Enforce bans or comprehensive restrictions on alcohol advertising, sponsorship and promotion; and
Raise prices on alcohol through excise taxes and pricing policies.
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orientaciones provisionales, primera publicación: 24 de mayo de 2021, actualización: 21 de octubre de 2021, actualización: 15 de marzo de 2022
Tuberculosis (TB) is, and should be, a curable disease; however, each year significant numbers of patients acquire or develop drug-resistant TB, which has a much lower cure rate. Patients with drug-resistant TB have a high prevalence of symptoms; hence, staff caring for these patients should h...ave some familiarity with palliative care, so that general palliative care principles are available to all patients. The timely identification, and addressing, of adverse events occurring during the treatment course is considered as general palliative care for those receiving curative treatment. This publication summarizes the general palliative care approach, which is recommended for use in settings and services that occasionally treat palliative care patients, but do not provide palliative care as the main focus of their work. The review focuses on 18 high TB priority countries of the WHO European Region.
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This brief summarizes current evidence and guidance for maintaining safe and effective care across the spectrum of maternal, newborn and infant care while protecting mother and child and health care providers during COVID-19. Furthermore, implications of the principle of “do no harm” are reviewe...d for maternal, newborn and infant care delivery during COVID-19, so that this information is conveniently and readily available to clinical and health system policy leaders and stakeholders in countries and communities. Additionally, considerations for safe oxygen delivery as well as key Infection Prevention and Control (IPC) measures at home and in healthcare facilities for pregnant women, newborns and children are described in detail in the brief.
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People-centered approaches that help communities maintain protective behaviours and follow guidelines set out by public health and government agencies are more important than ever. The evidence is clear, communities play a role in preventing and controlling epidemics and they are best able to take a...ction and slow or stop the spread of disease when properly engaged and empowered. This toolbox in 2 parts offers best practice approaches to community engagement with families. Promoting individual and joint responsibilities for the safety of the family, this toolbox aims to bring families and households together to manage shared risks and agree to safe behaviours critical for their safety and the safety of their community.
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Scientific Brief, 17 June 2021
Interim guidanceAnnex to: Policy considerations for implementing a risk-based approach to international travel in the context of COVID-19, 2 July 2021
This publication is based on the list of clinical interventions selected from clinical guidelines on prevention, screening, diagnosis, treatment, palliative care, monitoring and end of life care. This publication addresses medical devices for six types of cancer: breast, cervical, colorectal, leukem...ia, lung and prostate. The first section defines the global increase in cancer cases, the global goals to manage NCDs and the WHO activities related to these goals. The second section presents the methodology used for the selection of medical devices that support clinical interventions required to screen, diagnose, treat and monitor cancer stages, as well as the provision of palliative care, based on evidence-based information. The third section lists the priority medical devices required to manage cancer in seven different units of health care services: 1. Vaccination, clinical assessment and endoscopy, 2. Medical imaging and nuclear medicine, 3. Surgery, 4. Laboratory and pathology, 5. Radiotherapy, 6. Systemic therapy and 7. Palliative and end of life care
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Updated May 2021. Manual 3. The Practical Approach to Care Kit – PACK – is used by nurses, doctors and community health workers in their everyday work to care for patients at the clinic and in the community –PACK Adult, PACK Adolescent, PACK Child and PACK Community.PACK Home is designed for p...eople seeking more information about how to care for their own health and the health of their family at home.Collect and read all the PACK Home volumes in English, Afrikaans, isiXhosa, isiZulu or Sesotho
Download the different languages: https://knowledgetranslation.co.za/pack/pack-home/
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Practical Approach to Care Kit
Kit de Cuidados em Atenção Primária
Guia de manejo clínico da COVID 19 para Atenção Primária
O PACK Brasil é uma parceria entre a Unidade de Tradução do Conhecimento (KTU), Secretaria Municipal de Saúde de Florianópolis/SC, BMJ e Fundação ProAR. A Fund...ação ProAR é a líder oficial das atividades do PACK no Brasil. Mais informações sobre a ProAR podem ser encontradas em: www.fundacaoproar.org.br
O PACK foi adaptado, traduzido, implementado e avaliado em serviços de atenção primária brasileiros entre 2015 e 2017. Um ensaio clínico randomizado concluiu que o PACK qualificou o atendimento clínico de pacientes adultos com doenças respiratórias crônicas na atenção primária e apoiou o compartilhamento do cuidado entre médicos e enfermeiros. Desde então, foi revisado anualmente, estando alinhado com as políticas públicas locais. Em 2021, foi desenvolvido conteúdos adicionais sobre o manejo da COVID-19.
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