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1
This document highlights the latest WHO recommendations designed to optimize health outcomes, streamline delivery and address persistent barriers to prevention and care. It especially focuses on people often left behind in service delivery, includin
...
g adolescents and young people, key populations and people with advanced HIV disease. The guidance emphasizes integration, simplification, choice and equity.
more
The World Health Organization recently redefined leprosy elimination as a phased process, with the first milestone being the
interruption of transmission, achieved when no new child cases (defined as younger than 15 years) are reported for five con
...
secutive years.
In Pakistan, the well-functioning leprosy programme, with effective case management, context-specific active case-finding strategies and
a robust data management system, has contributed to a decrease in new cases. Between 2001 and 2023, new adult cases dropped by 75%
(from 878 cases to 220 cases annually) and child cases by 83% (from 93 to 16). To support the country’s goal of no new child cases by 2030
and ultimately eliminate the disease, the nongovernmental organizations Marie Adelaide Leprosy Centre and Aid to Leprosy Patients, with
support from the German Leprosy and Tuberculosis Relief Association, have developed a zero leprosy roadmap. As part of this roadmap,
the leprosy elimination strategy emphasizes improving active case-finding and providing post-exposure prophylaxis for contacts of leprosy
cases, who are at the highest risk
more
The objective of this guideline is to present the complete set of all WHO recommendations and best practice statements relating to abortion. While legal, regulatory, policy and service-delivery contexts may vary from country to country, the recommendations and best practices described in this docume
...
nt aim to enable evidence-based decision-making with respect to quality abortion care.
more
On 4 September 2025, the Ministry of Health of the Democratic Republic of the Congo (DRC) declared an outbreak of Ebola Virus Disease (EVD) in Kasai Province, following confirmation of Zaire ebolavirus by the National Institute of Biomedical Researc
...
h (INRB) in Bulape and Mweka Health Zones. As of 19 September, there have been 48 total cases (38 confirmed, 10 probable) with 31 deaths (21 confirmed, 10 probable) and a CFR of 64.5%. Among laboratory confirmed cases, 16 deaths were recorded (CFR: 45.7%). Four deaths occurred among health workers, underscoring the risk of nosocomial transmission. Most cases (39.7%) are among adults aged 20 years and above, in a densely populated, remote, and under-resourced area.
The outbreak is driven by multiple risk factors, including transmission in health facilities with limited infection prevention and control (IPC) measures and personal protective equipment (PPE), incomplete contact tracing, delayed detection, and unsafe burial practices. High population mobility between Bulape and Tshikapa, reliance on traditional healers, and the concurrent mpox outbreak are further straining the fragile health system and increasing the risk of geographic spread.
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Building on the WHO guidelines for disclosure to children up to age 12 in 2011, this implementation guidance provides evidence on existing interventions that support children and adolescents living with HIV in the process of disclosure. It includes interventions that focuses on safe disclosure, as w
...
ell as supporting children and adolescents with onwards disclosure. Specifically, this brief collates existing interventions via a scoping review; assesses key interventions through a realist evaluation lens, identifying what works, for whom, and in what contexts; and highlights emerging considerations, key gaps, and key actions.
more
Adolescents and young adults aged 10-24 remain underserved in the global response against HIV. Combination prevention, treatment and care programmes use a mix of evidence-based interventions to meet the current HIV prevention needs of adolescents and young adults. However, there needs to be a focus
...
on priority interventions that are evidence-based, practical, contextual and sustainable. This document highlights interventions and recommendations that have passed through the evidence-based lens of the WHO.
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Polic brief. In this policy brief, we give an update on those parts of the guidelines which are relevant for men who have sex with men.
Policy brief. In this policy brief, we give an update on those parts of the guidelines which are relevant for sex workers
These 2025 guidelines respond to the need for better approaches to identify advanced HIV disease, improve the poor outcomes of people living with HIV being discharged from hospital and provide updated guidance for treatment for Kaposi’s sarcoma through evidence-informed recommendations. The public
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ation contains recommendations that are from previously published WHO guidelines documents on advanced HIV disease and introduces new recommendations that were developed in 2025.
more
WHO's Department for HIV, Tuberculosis, Hepatitis and Sexually Transmitted Infections (STIs) has consolidated all existing normative guidance on STIs into a single publication. Structured around 10 chapters that follow the STI prevention and care cascade, the handbook covers primary prevention, synd
...
romic management and asymptomatic case identification, diagnostics, treatment, partner management, surveillance, service delivery, and integration within primary health care, community-based clinics, or other platforms (HIV, sexual health, antenatal clinics, etc).
more
Successful retention and re-engagement in HIV care depends largely on the ability of the provider to involve and motivate patients to attend ongoing care
Guidelines for malaria vector control
recommended
Vector control is a vital component of malaria prevention, control and
elimination strategies because it can be highly effective in providing
personal protection and/or reducing disease transmission.
The aim of this document is to provide interim guidance for interventions to reduce the risk of maternal Zika virus infection and to manage potential complications during pregnancy. This guidance is based on the best available research evidence and covers areas prioritized by an international, multi
...
disciplinary group of health care professionals and other stakeholders. Specifically, it presents guidance for preventing Zika virus infection;antenatal care and management of women with infection; and care during pregnancy for all pregnant women living in affected areas, with the aim of optimizing health outcomes for mothers and newborns.
more
This guideline provides global, evidence-informed recommendations on daily iron supplementation in infants and children, as a public-health intervention for the prevention of anaemia and iron deficiency. It includes recommendations for iron suppleme
...
ntation in countries where malaria is prevalent.
more
Technical report
This manual aims to provide information about the methods for investigating outbreaks of hepatitis E, and measures for their prevention and control. In addition, the manual gives information about the causative agent – known as the hepatitis E virus (HEV) – its epidemiology ... , clinical manifestations of the disease and diagnosis. more
This manual aims to provide information about the methods for investigating outbreaks of hepatitis E, and measures for their prevention and control. In addition, the manual gives information about the causative agent – known as the hepatitis E virus (HEV) – its epidemiology ... , clinical manifestations of the disease and diagnosis. more
