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Transmission of Ebola Viruses: What We Know and What We Do Not Know

Michael T. Osterholma, Kristine A. Moorea, Nicholas S. Kelley et al. (2015)
mBio, Vol. 6 Issue 2, March/April 2015 Available evidence demonstrates that direct patient contact and contact with infectious body fluids are the primary modes for Ebola virus transmission, but this is based on a limited number of studies. In this review, the authors address what we know and what ... more
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Sierra Leone: HIV Modes of Transmission and Prevention Response Analysis

National HIV and AIDS Secretariat; Patrick R. Kenya, Prince-Albert Roberts, Joseph Kobba, et al. (2010) C1
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LESOTHO HIV Prevention Response and Modes of Transmission Analysis

Lesotho National AIDS Commission, Government of Lesotho UNAIDS | GAMET (2009) C2
This study, and similar studies in Kenya, Mozambique, Swaziland, Uganda, and Zambia is the outcome of close collaborative by a team in Swaziland, with technical and financial support from the UNAIDS Regional Support Team for Eastern and Southern Africa, UNAIDS Geneva, and the World Bank's Global HIV... more
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Modes of HIV Transmission in Nigeria: Analysis of the Distribution of New HIV Infections in Nigeria and Recommendations for Prevention

National Agency for the Control of AIDS (NACA); UNAIDS; World Bank et al. (2010) C1
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Antibiotic resistance: using a cultural contexts of health approach to address a global health challenge

Ledingham, K. World Health Organization Europe (2020) C_WHO
This policy brief has been developed in response to the contemporary challenge of antibiotic resistance (‎ABR)‎. ABR poses a formidable threat to global health and sustainable development. It is now increasingly recognized that the systematic neglect of cultural factors is one of the biggest obs... more
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Recommendations for laboratory diagnosis of TB during the COVID-19 pandemic

Pan American Health Organization PAHO, World Health Organization WHO (2020) C_WHO
Given the current situation of the COVID-19 pandemic, countries are advised to continue adopting the TB diagnostic algorithms recommended by PAHO / WHO. Despite the differences in the modes of transmission of TB and COVID-19, certain personal protection measures are relevant for both diseases. Rout... more
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An Overview of Current Social Distancing Measures and Required Evidence for Determining Optimal Time for Relaxing Such Measures

Pan American Health Organization PAHO (2020) C_WHO
In the context of an unprecedented event such as the COVID-19 pandemic, at present, the effectiveness of stringent social distancing and international traffic-related measures in decreasing the rate of spread of SARS-CoV-2, and related mortality, is inferred from empiric observations of their applic... more
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Iron Status of Burkinabé Adolescent Girls Predicts Malaria Risk in the Following Rainy Season

Brabin, L.; S. Gies; S. A. Roberts et al. MDPI (2020) CC
High levels of storage iron may increase malaria susceptibility. This risk has not been investigated in semi-immune adolescents. We investigated whether baseline iron status of nonpregnant adolescent girls living in a high malaria transmission area in Burkina Faso affected malaria risk during the fo... more
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Transmission du SARS-CoV-2 – Implications pour les précautions visant à prévenir l’infection

World Health Organization WHO (2020) C_WHO
Le présent document est une mise à jour du document d’information scientifique publié le 29 mars 2020 intitulé Modes of transmission of virus causing COVID-19: implications for infection prevention and control (IPC) precaution recommendations et comprend les nouvelles don... more
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Transmission modelling of environmentally persistent zoonotic diseases: a systematic review

Rees, E.M.; A. Minter, J. Edmunds et al. The Lancet (2021) CC
The Lancet Planetary Health Volume 5, ISSUE 7, e466-e478, July 01, 2021 Transmission of many infectious diseases depends on interactions between humans, animals, and the environment. Incorporating these complex processes in transmission dynamic models can help inform policy and disease control int... more
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Modelling the effects of global climate change on Chikungunya transmission in the 21st century

Tjaden, N.B.; J.E. Suk, D. Fischer et al. Nature Scientific Reports (2017) CC
The arrival and rapid spread of the mosquito-borne viral disease Chikungunya across the Americas is one of the most significant public health developments of recent years, preceding and mirroring the subsequent spread of Zika. Globalization in trade and travel can lead to the importation of these vi... more
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Projecting the risk of mosquito-borne diseases in a warmer and more populated world: a multi-model, multi-scenario intercomparison modelling study

Colón-González, F.J.; M. Odhiambo Sewe, A.M Tompkins et al. The Lancet (2021) CC
Mosquito-borne diseases are expanding their range, and re-emerging in areas where they had subsided for decades. The extent to which climate change influences the transmission suitability and population at risk of mosquito-borne diseases across different altitudes and population densities has not be... more
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Understanding the transmission of Mycobacterium ulcerans: A step towards controlling Buruli ulcer

Muleta, A.J., R. Lappan, T. P. Stinear, et al. PLoS Neglected Tropical Diseases (2021) CC
August 26, 2021 https://doi.org/10.1371/journal.pntd.0009678
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First meeting of the network on Buruli ulcer PCR laboratories in the WHO African Region Centre Pasteur du Cameroon, Yaoundé, 21–24 October 2019

World Health Organization WHO (2020) CC
Buruli ulcer is caused by infection with Mycobacterium ulcerans. The disease is reported in more than 33 countries worldwide, but only about half of these countries regularly report data to WHO; most cases are reported from subregions of West and Central Africa. The mode of transmission is not known... more
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Congenital Chagas disease: Updated recommendations for prevention, diagnosis, treatment, and follow-up of newborns and siblings, girls, women of childbearing age, and pregnant women

Carlier, Y.; Altcheh, J.; Angheben, A. et al. PLOS Neglected Tropical Diseases (2019) CC
In 2005, the World Health Organization (WHO) recognized Chagas disease (CD; Trypanosoma cruzi infection) as a neglected tropical disease (NTD) [1] and included it into the global plan to combat NTDs [2]. The Target 3.3 of the United Nations Sustainable Development Goals (UN/SDG) aims at ending the e... more
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Geographical, landscape and host associations of Trypanosoma cruzi DTUs and lineages

Izeta-Alberdi, A.; Ibarra-Cerdena, C.; Moo-llanes, D.; Ramsey,J. BMC Part of Springer Nature (2016) CC
Trypanosoma cruzi is the etiological agent of Chagas disease (CD), considered one of the most important parasitic infections in Latin America. Between 25 and 90 million humans are at infection risk via at least one of multiple infection mechanisms. Under natural conditions, the principal transmissio... more
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Fexinidazole for Human African Trypanosomiasis, the Fruit of a Successful Public-Private Partnership.

Bernhard, S.; Kaiser, M.; Burri, C.; Mäser, P. Diseases (2022) CC
After 100 years of chemotherapy with impractical and toxic drugs, an oral cure for human African trypanosomiasis (HAT) is available: Fexinidazole. In this case, we review the history of drug discovery for HAT with special emphasis on the discovery, pre-clinical development, and operational challenge... more
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Epidemiology of Chagas disease in pregnant women and congenital transmission of Trypanosoma cruzi in the Americas: systematic review and meta-analysis

Santana, K.; Oliveira, L.; Barros de Castro, D. et al. Tropical medicine & international health (2020) CC
Objective To estimate the prevalence of Chagas disease in pregnant women and the vertical transmission of the disease. Methods Observational studies were identified from eight electronic databases, and details on study design, population and prevalence of Chagas disease were extracted. The data... more
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Report of the first WHO stakeholders meeting on rhodesiense human African trypanosomiasis Geneva, 20–22 October 2014

World Health Organization WHO (2014) C_WHO
The objectives of the meeting were: 1. To update the current status of the disease transmission, country capacities and plans for tackling the disease. 2. To understand the epidemiology including disease distribution and risk, the models for estimating under-detection, the geographical variati... more
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Assessing the feasibility of interrupting the transmission of soil-transmitted helminths through mass drug administration: The DeWorm3 cluster randomized trial protocol

Ásbjörnsdóttir K.H., Ajjampur S.S.R., Anderson R.M. et al (2018) C2
Soil-transmitted helminths (STH) affect 1.45 billion people worldwide, and high intensity infections are associated with anemia, undernutrition and impaired cognition, particularly among children. Mathematical models suggest it may be possible to interrupt the transmission of STH in a community by e... more