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Government of Sierra Leone; Centers for Disease Control and Prevention (2015)
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Estimating COVID-19 vaccine effectiveness against severe acute respiratory infections (SARI) hospitalisations associated with laboratory-confirmed SARS-CoV-2

World Health Organization WHO (2021) C_WHO
Many critical questions remain about the effectiveness of COVID-19 vaccines in real-world settings. These questions can only be answered in post-introduction vaccine effectiveness studies.This guidance document outlines an approach to leverage existing surveillance systems for Severe Acute Respirato... more
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Learn more about monkeypox as we record first confirmed case in SA

Saphra (2022) CC
South Africa has recorded its first case of monkeypox today, 23 June 2022. The Minister of Health Dr. Joe Phaahla explained that he received a report from the National Health Laboratory Services’ CEO that they have confirmed through laboratory tests the first case of monkeypox in South Africa. ... more
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Does the patient meet the case definition for a COVID-19 case?

Nation Institute for Communicable Diseases - Division of the National Health Laboratory Service Department: Health Republic of South Africa (2020) C2
Persons with acute respiratory illness with sudden onset of at least one of the following: cough, sore throat, shortness of breath or fever [≥ 38°C (measured) or history of fever (subjective)] irrespective of admission status AND In the 14 days prior to onset of symptoms, met at least one of the ... more
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An update on rabies in South Africa, 2021

National Institute for Communicable Disease NICD (2021) CC
As of 14 December 2021, a total of 19 laboratory-confirmed human rabies cases has been reported in South Africa for 2021. The cases are from Eastern Cape, KwaZuluNatal and Limpopo provinces. In addition, four probable rabies cases were reported from KwaZulu-Natal and the Eastern Cape provinces. A pr... more
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Lessons Learnt from Epidemiological Investigation of Lassa Fever Outbreak in a Southwest State of Nigeria December 2015 to April 2016

Isere, Elvis Efe; Fatiregun, Akinola Ayoola et al. (2018) CC
Plos Current Outbreaks An outbreak of Lassa Fever (LF) reported and confirmed in Ondo state, Southwest Nigeria in January 2016 was investigated. This paper provides the epidemiology of the LF and lessons learnt from the investigation of the outbreak.
Results: We identified 90 suspected LF case... more
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Protocol for assessment of potential risk factors for 2019-novel coronavirus (2019-nCoV) infection among health care workers in a health care setting
recommended

World Health Organization WHO (2020) C_WHO
This is a case-ascertained prospective investigation of all identified health care contacts working in a health care facility in which a laboratory confirmed 2019-nCoV infected patient (see 2.2 Study population) receives care. Note that this study can be done in health care facilities at all 3 level... more
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Household transmission investigation protocol for 2019-novel coronavirus (2019-nCoV) infection
recommended

World Health Organization WHO (2020) C_WHO
The household transmission investigation is a case-ascertained prospective study of all identified household contacts of a laboratory confirmed 2019-nCoV infection (see 2.2 Study population). It is intended to provide rapid and early information on the clinical, epidemiological and virological chara... more
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Ebola: Clinical management of Ebola virus disease
recommended

World Health Organization (WHO) (2018) C_WHO
This comprehensive intermediate level course is for clinicians caring for patients with suspected or confirmed Ebola virus disease (EVD). Modules provide information on screening and triage, infection prevention and control, laboratory diagnostics, organization of the Ebola Treatment Centre (ETC), c... more
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Epidemiological Update - Dengue - 9 August 2019

World Health Organization, Pan American Health Organization (2019) C_WHO
In the Region of the Americas, between epidemiological week (EW) 1 and EW 52 of 2018, a total of 560,586 cases of dengue were reported (incidence rate of 57.3 cases per 100,000 population), including 336 deaths. Of the total cases, 209,192 (37.3%) were laboratoryconfirmed and 3,535 (0.63%) were clas... more
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Syria AWD/Cholera Response Plan September 2022 (as of 29 September 2022)

World Health Organization WHO (2022) C_WHO
On September 10, 2022, the Ministry of Health (MOH) announced a cholera outbreak in Aleppo governorate with 15 laboratory confirmed cases reported between August 25 and September 9, 2022. Activities under this plan seek to address the immediate needs stemming from this outbreak and highlight respons... more
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COVID-19 in Yemen: preparedness measures in a fragile state

Dureab, F.; S. Al-Awlaqi and A.Jahn The Lancet (2020) CC
The Lancet DOI: 10.1016/S2468-2667(20)30101-8 WHO declared COVID-19 to be a pandemic on March 11, 2020. The pandemic eventually reached Yemen, with the first laboratory confirmed case announced on April 10. emen has structural vulnerabilities that have developed over a protracted period of conflic... more
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SARS-CoV-2 Seroprevalence in a Rural and Urban Household Cohort during First and Second Waves of Infections, South Africa, July 2020–March 2021

Kleynhans, J.; et al. (2021) C_CDC
EID Journal , Volume 27, no.12 , Dec. 2021. Early Release Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections may be underestimated because of limited access to testing. We measured SARS-CoV-2 seroprevalence in South Africa every 2 months during July 2020–March 2021 in randoml... more
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Interim Guidelines on Management of COVID-19 in Kenya - COVID-19, Infection Prevention and Control (IPC) and Case Management

Dr. P. Amoth; Dr. S. K. Kibias Ministry of Health; University of Nairobi (2020) C2
Accessed: 02.05.2020 These consolidated guidelines provide recommendations for comprehensive prevention and case management strategies in Kenya Scope of the Guidelines: Infection prevention and control Patient triage Emergency Medical Services Case management Laboratory testing algorithm Target... more
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Epidemiological Update: Dengue. 7 February 2020

World Health Organization WHO Pan American Health Organization PAHO PAHO (2020) CC
Epidemiological Update Dengue 7 February 2020 Situation summary In the Region of the Americas, between epidemiological week (EW) 1 and EW 521 of 2019, a total of 3,139,335 cases of dengue have been reported (321.58 cases per 100,000 population), including 1,538 deaths. Of the total cases, 1,367,... more
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Disease Outbreak News Marburg virus disease - Rwanda

World Health Organisation (WHO) (2024) C_WHO
On 27 September 2024, the Rwanda Ministry of Health announced the confirmation of Marburg virus disease (MVD). Blood samples taken from people showing symptoms were tested by real-time reverse transcription polymerase chain reaction (RT-PCR) at the National Reference Laboratory of the Rwanda Biomedi... more
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Prevalence, Etiology, and Outcome of Sepsis among Critically Ill Patients in Malawi

Prin, M.; Onofrey, L.; Purcell, L; et al. (2020) CC2
Most of the global burden of sepsis occurs in low- and middle-income countries (LMICs), but the prevalence and etiology of sepsis in LMICs are not well understood. In particular, the lack of laboratory infrastructure in many LMICs has historically precluded an assessment of the pathogens leading to ... more
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Global Antimicrobial Resistance and Use Surveillance System (GLASS) Report: 2021

World Health Organization WHO (2021) C_WHO
9 June 2021 Since its launch, GLASS has expanded in scope and coverage and as of May 2021, 109 countries and territories worldwide have enrolled in GLASS. A key new component in GLASS is the inclusion of antimicrobial consumption (AMC) surveillance at the national level highlighted in this fourth G... more
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Clinical Management of Yellow Fever in the Region of the Americas. Experiences and Recommendations for Health Services

Pan American Health Organisation PAHO (2023) CC
The waves of yellow fever transmission in the Region of the Americas in 2016–2018 involved the largest number of human and epizootic cases to be reported in several decades. Yellow fever is a serious viral hemorrhagic disease that poses a challenge for health professionals. It requires early recog... more
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Lessons Learnt from the Marburg Virus Disease (MVD) Outbreak in Tanzania

Africa CDC (2023) C_CDC
On March 16, 2023, the Tanzania Ministry of Health declared an outbreak of an unidentified illness in Bukoba district, Kagera region. A group of seven individuals presented with fever, vomiting, bleeding from various body orifices, and kidney failure, sparking suspicion of a contagious disease. Labo... more