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Guidance on sampling techniques for laboratory-confirmation of Mycobacterium ulcerans infection (Buruli ulcer disease)

World Health Organization WHO (2008) C_WHO
Guidance
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Laboratory biosafety manual
recommended

World Health Organization WHO WHO (2020) C_WHO
4th edition The WHO Laboratory Biosafety Manual (LBM) has been in broad use at all levels of clinical and public health laboratories, and other biomedical sectors globally, serving as a de facto global standard that presents best practices and sets trends in biosafety. LBM encouraged countries t... more
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Laboratory testing for Zika virus and dengue virus infections: interim guidance
recommended

World Health Organization (2022) C_WHO
Zika and dengue viruses remain significant public health threats. These viruses share the same Aedes (Stegomyia) mosquito vectors and geographic distributions but infections cannot be readily distinguished clinically and need to be differentiated from each other, and from other circulating arboviral... more
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Laboratory diagnosis of Buruli ulcer
recommended

Portaels, F- World Health Organization WHO (2014) C_WHO
A manual for health care providers. This manual provides expert guidance on the laboratory techniques and procedures used in the diagnosis of Buruli ulcer, a disease caused by Mycobacterium ulcerans. Aimed at laboratory technicians and scientists working on this disease, the manual details the exac... more
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Laboratory biosafety guidance related to coronavirus disease (COVID-19): Interim guidance, 28 January 2021
recommended

World Health Organization WHO (2021) C_WHO
The latest update (28 January 2021) includes the following addition and revision: biosafety aspects for working with antigen-detecting rapid diagnostic test; handling new variants of SARS-CoV-2 in the laboratory; updated assay decontamination before disposal; personal protectiv... more
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Guidelines for laboratory and field testing of molluscicides for control of schistosomiasis

World Health Organization WHO (2019) C_WHO
This document provides up-to-date guidance on laboratory studies as well as smallscale (semi-field) and large-scale field trials to assess the efficacy and determine field application rates of new molluscicide products for control of schistosomiasis.
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Buruli ulcer laboratory network and new external quality assessment programme for PCR-based diagnosis in the WHO African Region. Terms of reference

World Health Organization WHO (2020) C_WHO
A total of 18 laboratories from 13 countries participated in the four rounds of EQA: 10 laboratories from eight African endemic countries, four of which participated in all four rounds and three in three rounds. The overall results showed that the median performance of these laboratories improved ov... more
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ECDC rapid assessment of laboratory practices and needs related to COVID-19

European Centre for Disease Prevention and Control ECDC (2021) C1
18 Janaury 2021 EU/EEA Member States and the UK have increased their laboratory capacity tremendously over the past 11 months as the majority of the Member States reported sufficient testing capacity until March 2021. Many countries are adding rapid antigen detection tests (RADT) to their ... more
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Laboratory testing for COVID-19

World Health Organization WHO, Regional Office of Africa (2021) C_WHO
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Laboratory biosafety guidance related to coronavirus disease (COVID-19) , Arabic Version

World Health Organization WHO (2021) C_WHO
28 January 2021. The purpose of this document is to provide interim guidance on laboratory biosafety related to the testing of clinical specimens of patients.
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Laboratory testing for the monkeypox virus
recommended

World Health Organization (WHO) (2022) C_WHO
Any individual that meets the suspected case definition of monkeypox should be offered testing in appropriately equipped laboratories by staff trained in the relevant technical and safety procedures. Confirmation of monkeypox virus infection is based on nucleic acid amplification testing (NAAT), usi... more
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Laboratory testing for severe acute hepatitis of unknown aetiology in children: interim guidance, 17 June 2022

World Health Organization WHO (2022) C_WHO
This document provides interim guidance to countries on testing considerations and strategies for suspect cases of severe acute hepatitis of unknown aetiology in children. It is primarily intended for clinical, programmatic, laboratory and diagnostic stakeholders across Member States and national pu... more
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Laboratory Guidelines for the Detection and Diagnosis of Monkeypox Virus Infection

Pan American Health Organisation PAHO (2022) C_WHO
15 May 2022
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Manual de Biossegurança Laboratorial
recommended

World Health Organization WHO (2021) C_WHO
Quarta Edição. Esta quarta edição do manual se baseia no esquema de avaliação de risco apresentado na terceira edição. Uma avaliação completa, baseada em evidências e transparente dos riscos permite que as medidas de segurança sejam equilibradas com o risco real de trabalhar com agentes... more
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Laboratory Tests Used in the Diagnostic and Research of Dengue Virus: Present and Future

Juan Samuel Sulca Herencia IntechOpen (2018) CC
Dengue is a significant public health problem. There are four dengue virus serotypes identified; however, its diagnosis is difficult due to the existence of many viruses, bacteria, and parasites producing the same clinical presentation, being present in the same geographical area and even producing ... more
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Laboratory techniques in rabies

Rupprecht, C.; Fooks, A,; Abela-Ridder, B. World Health Organization WHO (2018) C_WHO
Rabies has an enormous impact on both agriculture and conservation biology, but its greatest burden is undeniably on public health. As such, routine methods for rapid risk assessment after human exposures to rabies as well as applications for laboratory-based surveillance, production of biologicals ... more
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Laboratory techniques in rabies Fifth edition Volume 2

Rupprecht, C.; Fooks, A.; Abela-Ridder, B. World Health Organization WHO (2019) C_WHO
Rabies has an enormous impact on both agriculture and conservation biology, but its greatest burden is undeniably on public health. As such, routine methods for rapid risk assessment after human exposures to rabies as well as applications for laboratory-based surveillance, production of biologicals ... more
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Laboratory and point-of-care diagnostic testing for sexually transmitted infections, including HIV

World Health Organization WHO (2023) C_WHO
This updated manual provides a basic understanding of the principles of laboratory and point-of-care (POC) testing in the context of screening and diagnostic approaches, as well as antimicrobial susceptibility testing, as components of sexually transmitted infections (STIs) control. As with previous... more
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Laboratory testing for diphtheria in outbreak settings: Interim guidance, 26 January 2024

World Health Organization WHO (2024) C_WHO
This document provides detailed guidance on laboratory testing for suspected diphtheria cases during significant outbreaks or in low-resource settings. It aims to supplement and build on other existing WHO guidance documents on surveillance standards, diagnostics and research on Corynebacterium by p... more
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Laboratory manual for yellow fever
recommended

World Health Organization WHO (2024) C_WHO
This WHO laboratory manual provides the most up to date methods and procedures for the laboratory identification of yellow fever virus infection in humans. It provides guidance on the establishment and maintenance of an effective laboratory providing routine surveillance testing for yellow fever, wh... more