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A practical handbook on the pharmacovigilance of antiretroviral medicines

World Health Organization WHO (2013) C_WHO
This is a detailed manual giving a step by step approach to undertaking the pharmacovigilance of antiretrovirals. It is intended to be a source of practical advice for Pharmacovigilance Centres and health professionals involved in HIV/AIDS prevention and treatment programmes. A number of WHO publica... more
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Sierra Leone: A Guide for Detecting and Reporting adverse Drug Reactions

Drug Safety Monitoring Programme; Pharmacy Board Sierra Leone; Ministry of Health and Sanitation Sierra Leone (2005) C1
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Drug use and road safety

World Health Organization (2016) C_WHO
Psychoactive substance use affects the functioning of the brain and leads to impaired driving
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Blueprint for a Public Health and Safety Approach to Drug Policy

Tracy Pugh, Julie Netherland, Ruth Finkelstein The New York Academy of Medicine, Drug Policy Alliance (2013) C2
"Some of the problems with our current drug policies stem from the fact that these policies have been largely bifurcated between two different and often contradictory approaches. One treats drug use as a crime that cannot be tolerated and should be punished; the other views addiction as a chronic re... more
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Safety Monitoring of medicinal products

Uppsala Monitoring Centre World Health Organization (2012) C_WHO
Reporting system for the general public - This document aims to provide practical guidelines on how to set up national systems for consumers to report adverse reactions to medicines. The purpose is to help countries set up a well-organized and effective consumer reporting system within their pharmac... more
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Treatment of Drug-Resistant TB with New and Repurposed Medications: A Supplemental Field Guide for Nurses

The SWIFT Response Project (2015) C_WHO
For the first time in almost 50 years there are two new drugs for the treatment of drug-resistant TB (DR-TB): bedaquiline and delamanid. There has also been increased attention given to the safety and efficacy of “re-purposed” drugs that have been widely used to treat other infections but are al... more
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Active tuberculosis drug-safety monitoring and management (aDSM)

World Health Organization (2015) C_WHO
Framework for implementation. The END TB Strategy.
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Ghana: GUIDELINES FOR SAFETY MONITORING OF MEDICINAL PRODUCTS

Food and Drug Authority (FDA), Ghana (2016) C2
Document No. : FDA/SMC/SMD/GL-SMP/2015/05 | These guidelines are for information, guidance and strict compliance by Marketing Authorization Holders and Local Representatives of regulated products to help in the continuous safety monitoring of products granted marketing authorization in Ghana.
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WHO recommendations on active drug safety management and monitoring (aDSM) for new drugs and regimens

D. Falzon, USAID, Asia Regional Pharmacovigilance World Health Organization (2017) C_WHO
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GUIDELINES FOR DETECTING AND REPORTING ADVERSE DRUG OR VACCINE REACTIONS AND EVENTS IN ZAMBIA

Zambia Medicines Regulatory Authority (ZAMRA) (2006) C2
The safety of medicines in Zambia - why health workers need to take action | Produced by the National Pharmacovigilance Unit (NPVU)
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Safety in administering medicines for neglected tropical diseases

World Health Organization WHO (2021) C_WHO
This manual summarizes key issues related to the safety of NTD medicines and their administration, with a focus on essential medicines used in mass drug administration (MDA), also called preventive chemotherapy. It can be used as a standalone reference manual, but is intended to be used in conjuncti... more
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Drug-resistant TB Treatment

World Health Organization WHO (2021) C_WHO
This e-course will guide you through the essentials of latest existing WHO guidelines and policy recommendations on drug-resistant TB. You will also learn more about the rationale behind the WHO recommendations for the management of DR-TB, implementation considerations for different regimens for eli... more
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Drug Regulation in Kenya

LEAP (2021) CC
Drug registration in Kenya started in 1982; the process mainly involves an evaluation committee at the Kenya Pharmacy and Poisons Board (PPB) that aims to approve products based on quality, safety and efficacy.
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Guideline for Adverse Drug Reactions Reporting for Healthcare Professionals

SAHPRA (2020) CC
Communication to Healthcare Professionals Mar-2020 This guideline is intended to assist healthcare professionals in the participation of very important process of continuous surveillance of safety and efficacy of the health products which are used in their clinical practice. Continuous evaluation o... more
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Investing in drug-resistant tuberculosis household contact management and preventive treatment

Hussain.H.; Malik, A. A. The Lancet (2022) CC
Preventing tuberculosis infection from progressing to tuberculosis disease is a crucial component of the goal to eliminate tuberculosis. When deciding on the use of tuberculosis preventive therapy among household contacts, policy makers regularly ask questions, such as whether tuberculosis preventiv... more
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Drug misuse: opoid detoxification

National Collaborating Centre for Mental Health NICE (2008) C1
The guideline on Drug misuse: opioid detoxification, commissioned by NICE and developed by the National Collaborating Centre for Mental Health, sets out clear, evidence-based recommendations for healthcare staff on how to work with people who misuse opioids to significantly improve their treatment a... more
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Ethiopian Food and Drug Authority Website

Ethiopian Food and Drug Authority (2022) CC
The Ethiopian Food and Drug Administration (EFDA) is mandated, in the proclamation 661/2009, to ensure the safety, quality and efficacy of medicines. To achieve this, the authority has been working on different regulatory activities. The medicine market authorization system is one of the top priorit... more
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Efficacy and Safety of Pafuramidine versus Pentamidine Maleate for Treatment of First Stage Sleeping Sickness in a Randomized, Comparator-Controlled, International Phase 3 Clinical Trial

Pohlig G, Bernhard SC, Blum J, Burri C, Mpanya A, et al. PLOS Neclected Tropical Diseases (2016) CC
This was a Phase 3, multi-center, randomized, open-label, parallel-group, active control study where 273 male and female patients with first stage Trypanosoma brucei gambiense HAT were treated at six sites: one trypanosomiasis reference center in Angola, one hospital in South Sudan, and four hospita... more
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An open label, block randomized, community study of the safety and efficacy of coadministered ivermectin, diethylcarbamazine plus albendazole vs. diethylcarbamazine plus albendazole for lymphatic fila

JambulingamI P. , KuttiattI V.S., Krishnamoorthy K. et al (2021) C2
Better drug regimens for mass drug administration (MDA) could accelerate the Global Programme to Eliminate Lymphatic Filariasis (LF). This community study was designed to compare the safety and efficacy of MDA with IDA (ivermectin, diethylcarbamazine and albendazole) or DA (diethylcarbamazine and ... more
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Enhancing Pharmacovigilance in Sub‑Saharan Africa Through Training and Mentoring: A GSK Pilot Initiative in Malawi

Jusot, V.; Chimimba, F.; Dzabala, N. et al. Drug Safety (2020) CC
Introduction Pharmacovigilance (PV) systems to monitor drug and vaccine safety are often inadequate in sub-Saharan Africa. In Malawi, a PV enhancement initiative was introduced to address major barriers to PV. Objective The objective of this initiative was to improve reporting of adverse events (A... more