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Isoniazid Preventive Therapy and Risk for Resistant Tuberculosis

M. E. Balcells, S. L. Thomas, P. Godfrey-Faussett, et al. (2006) C_CDC
Research Emerging Infectious Diseases Vol. 12, No. 5, May 2006
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Efficacy of isoniazid prophylactic therapy in prevention of tuberculosis in children: a meta–analysis

J. Ayieko, L. Abuogi, B. Simchowitz, et al. BMC Infectious Diseases (2014) CC
Research Article BMC Infectious Diseases 2014, 14:91/1471-2334/14/91
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HIV Programme Review in Albania: Antiretroviral therapy and procurement and supply management

J. V. Lazarus; M. Gottfredsson; N. Tavagnutti World Health Organization (Europe); Centre for Health & Infectious Disease Research (2015) C_WHO
March 2015
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Key considerations for differentiated antiretroviral therapy delivery for specific populations: Children, adolescents, pregnant and breastfeeding women and key populations

World Health Organization; (CDC) Center for disease control and prevention; USAID; et al. (2017) C_WHO
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Guidelines for managing advanced HIV disease and rapid initiation of antiretroviral therapy

World Health Organization (WHO) (2017) C_WHO
The objectives of these guidelines are to provide recommendations outlining a public health approach to managing people presenting with advanced HIV disease, and to provide guidance on the timing of initiation of antiretroviral therapy (ART) for all people living with HIV.
WHO recommends that a... more
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Optimized Supportive Care for Ebola Virus Disease
recommended

World Health Organization WHO (2019) C_WHO
Clinical management standard operating procedures. Ebola virus disease (EVD) is a life-threatening multisystem illness associated with fever and gastrointestinal (GI) symptoms that frequently leads to hypovolaemia, metabolic acidosis, hypoglycaemia, and multi-organ failure. The prolonged 2013–201... more
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Home-based therapeutic exercise as a treatment for Parkinson's Disease: an integrative review

Ihana Thaís Guerra de Oliveira Gondim; Carla Cabral dos Santos Accioly Lins; Maria das Graças Wanderley de Sales Coriolano Revista Brasileira de Geriatria e Gerontologia; SCIELO (2016) C2
Print version ISSN 1809-9823On-line version ISSN 1981-2256 Rev. bras. geriatr. gerontol. vol.19 no.2 Rio de Janeiro Mar./Apr. 2016 http://dx.doi.org/10.1590/1809-98232016019.150040
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Incidence and Prevalence of Opportunistic and Other Infections and the Impact of Antiretroviral Therapy Among HIV-infected Children in Low- and Middle- income Countries: A Systematic Review and Meta-a

M.-R. B-Lajoie; O. Drouin; G. Bartlett; et al. Clinical Infectious Diseases; Infectious Diseases Society of America (IDSA); hivma; Oxford; WHO (2016) C2
Clinical Infectious Diseases 1586 - 1594 • CID 2016:62 (15 June) • HIV/AIDS
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Policy Brief to Guidelines for managing advanced HIV disease and rapid initiation of antiretroviral therapy

World Health Organization (2017) C_WHO
HIV treatment Policy brief July 2017 WHO/HIV/2017.18
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Profiles of Peripheral CD4+T Cells Count during Antiretroviral Treatment in Senegalese Adults Infected by HIV: Impact of Therapeutic Associations

Niang M. S., R. Derwiche, B. Mbengue Journal of Immunology, Infection & Inflammatory Diseases (2017) CC
Thirty-three years after its discovery, the Human Immunodeficiency Virus (HIV), responsible for the AIDS pandemic, remains a major public health problem despite advanced researches providing better diagnostic and therapeutic tools. The virus targets especially CD4+ T cells, leading to deficiency of ... more
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Review Challenges in Chagas Disease Drug Development

Francisco, A.; Jayawardhana, S.; Olmo, F. et al. Molecules MDPI (2020) CC
The protozoan parasite Trypanosoma cruzi causes Chagas disease, an important public health problem throughout Latin America. Current therapeutic options are characterised by limited efficacy, long treatment regimens and frequent toxic side-effects. Advances in this area have been compromised by gaps... more
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Advances in preclinical approaches to Chagas disease drug discovery

Villalta, F.; Rachakonda, G. (2019) CC
Chagas disease affects 8-10 million people worldwide, mainly in Latin America. The current therapy for Chagas disease is limited to nifurtimox and benznidazole, which are effective in treating only the acute phase of the disease but with severe side effects. Therefore, there is an unmet need for new... more
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New Therapeutics for Chagas Disease: Charting a Course to Drug Approval

Man, A. & Segal, F. IntechOpen (2022) CC
Little progress has been made since the 1960s and 1970s to widen the therapeutic arsenal against Trypanosoma cruzi, the causative pathogen of Chagas disease, which remains a frustrating and perplexing infectious disease. This chapter focuses on the strategic and operational challenges in the clinica... more
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A systematic review of historical and current trends in Chagas disease

Álvarez-Hernández D., García-Rodríguez-Arana R., Ortiz-Hernández A. et al. Therapeutic advances in infectious disease (2021) CC
Chagas disease (CD) is caused by Trypanosoma cruzi. When acquired, the disease develops in stages. For diagnosis, laboratory confirmation is required, and an extensive assessment of the patient’s health should be performed. Treatment consists of the administration of trypanocidal drugs, which may... more
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Recent Trends in Leishmania Research: A Therapeutic Perspective

Jawed, J. & Majumdar, S. Journal of Infectiology and Epidemiology (2018) CC
Leishmaniasis is a spectrum of disease caused by the infection of protozoan parasite Leishmania mainly affecting the antigen presenting cell of the host. The disease is although considered as neglected tropical disease still it is not completely eradicated. Majority of the issues related to the ther... more
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The Challenges of Conducting Clinical Research on Neglected Tropical Diseases in Remote Endemic Areas in Sudan

El-Safi, S.; Chappuis, F.; Boelaert, M. PLoS Neglected Tropical diseases (2016) CC
Most neglected tropical diseases (NTDs) occur in remote areas of low- and middle-income countries, where health systems are often poorly developed. Therefore, these neglected patients generally lack access to quality preventive, diagnostic, and therapeutic care [1]. The difficulty to access NTD-ende... more
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Chromoblastomycosis: a neglected tropical disease

Scientific Electronic Library Online SciELO (2015) CC
Chromoblastomycosis (CMB) is a chronic fungal infection of the skin and the subcutaneous tissue caused by a transcutaneous traumatic inoculation of a specific group of dematiaceous fungi occurring mainly in tropical and subtropical zones worldwide. If not diagnosed at early stages, patients with CBM... more
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Acute schistosomiasis, a diagnostic and therapeutic challenge

Jauréguiberry S., Paris L., Caumes E. (2010) C2
Clin Microbiol Infect 2010; 16: 225–231 Abstract In non-endemic countries, acute (invasive) schistosomiasis (AS) is typically seen in non-immune travellers, whereas chronic schistosomiasis is more frequently diagnosed in immigrants. Travellers with AS initially present with non-specific signs such... more
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Diphtheria - Vaccine-Preventable Diseases Surveillance Standards

World Health Organization WHO (2018) C_WHO
Diphtheria is caused by Corynebacterium species, mostly by toxin-producing Corynebacterium diphtheriae and rarely by toxin-producing strains of C. ulcerans and C. pseudotuberculosis. The most common type of diphtheria is classic respiratory diphtheria, whereby the exotoxin produced characteristicall... more
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Global leprosy (Hansen disease) update, 2022: new paradigm – control to elimination

World Health Organization WHO (2023) C_WHO
ince the introduction of multidrug therapy (MDT), there has been significant progress in reducing the prevalence of leprosy and the occurrence of new cases. Global strategies have evolved with progress in reducing the disease burden. Encouraged by the decrease in the number of cases on treatment, th... more