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Investigating the zoonotic origin of the West African Ebola epidemic

Almudena Marí Saéz, Sabrina Weiss, Kathrin Nowak,et al. (2014)

DOI 10.15252/emmm.201404792 |Published online 30.12.2014 EMBO Molecular Medicine(2014)emmm.201404792

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Transmission of Ebola Viruses: What We Know and What We Do Not Know

Michael T. Osterholma, Kristine A. Moorea, Nicholas S. Kelley et al. (2015)

mBio, Vol. 6 Issue 2, March/April 2015 Available evidence demonstrates that direct patient contact and contact with infectious body fluids are the primary modes for Ebola virus transmission, but this is based on a limited number of studies. In this review, the authors address what we know and what ... more

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Practical recommendations to the attention of healthcare professionals and health authorities regarding the identification of and care delivered to suspected or confirmed carriers

Superior Health Council (2014)

of highly contagious viruses (of the Ebola or Marburg type) in the context of an epidemic outbreak in West Africa

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Laboratory testing for Zika virus and dengue virus infections: interim guidance
recommended

World Health Organization (2022) C_WHO

Zika and dengue viruses remain significant public health threats. These viruses share the same Aedes (Stegomyia) mosquito vectors and geographic distributions but infections cannot be readily distinguished clinically and need to be differentiated from each other, and from other circulating arboviral... more

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CS258303 National Center for Emerging and Zoonotic Infectious Diseases Division of Vector-Borne Diseases Help Control Mosquitoes that Spread Dengue, Chikungunya, and Zika Viruses

National Center for Emerging and Zoonotic Infectious Diseases Division of Vector-Borne Diseases (CDC) (2015) CC

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Nipah virus

World Health Organization WHO (2018) C_WHO

Fact Sheet, May 2018. Nipah virus (NiV) is a zoonotic virus (it is transmitted from animals to humans) and can also be transmitted through contaminated food or directly between people. In infected people, it causes a range of illnesses from asymptomatic (subclinical) infection to acute respiratory ... more

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Protecting people and animals from disease threats

Food and Agriculture Organization (FAO) (2018) C1

The Global Health Security Agenda programme develops national capacity to prevent zoonotic and non-zoonotic diseases while quickly and effectively detecting and controlling diseases when they do emerge. The Emerging Pandemic Threats programme improves national capacity to pre-empt the emergence and ... more

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Zoonotic diseases of public health importance

National Institue of communicable Diseases, India (1998) C1

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Multisectoral prioritization of zoonotic diseases in Uganda, 2017: A One Health perspective

Sekamatte, M.; V. Krishnasamy, L.Bulage et al. PLOS journals (2018) CC

PlosOne https://doi.org/10.1371/journal.pone.0196799; Zoonotic diseases continue to be a public health burden globally. Uganda is especially vulnerable due to its location, biodiversity, and population. Given these concerns, the Ugandan government in collaboration with the Global Health Security Age... more

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Building a global atlas of zoonotic viruses

Dennis, C.; B Watso, E.Togami et al. WHO (2018) C_WHO

Despite the human and economic impact of viral epidemics, the world is not well enough prepared for the next emerging viral outbreak. Global trends indicate that new microbial threats will continue to emerge at an accelerating rate, driven by our growing population, expanded travel and trade network... more

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Introducing One Health to the ethical debate about zoonontic diseases in Southeast Asia

Capps, B.; M.M. Bailey, D. Bickford et al. Bioethics (2015) CC

Bioethics 519 (online) doi:10.1111/bioe.12145 Volume 29 Number 8 2015 pp. 488–596; Pandemic plans recommend phases of response to an emergent infectious disease (EID) outbreak, and are primarily aimed at preventing and mitigating human-to-human transmission. These plans carry presumptive weight ... more

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A better classification of wet markets is key to safeguarding human health and biodiversity

Bing Lin A. B., M.L Dietrich, R.A.Senior, et al. The Lancet, Planetary Health (2021) CC

Wet markets have been implicated in multiple zoonotic outbreaks, including COVID-19. They are also a conduit for legal and illegal trade in wildlife, which threatens thousands of species. Yet wet markets supply food to millions of people around the world, and differ drastically in their physical com... more

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Emerging and re-emerging human infectious diseases: A systematic review of the role of wild animals with a focus on public health impact

Cupertino, M. C.; Resende, M. B.; et al (2020) C2

Infectious diseases continue to impose unpredictable burdens on global health and economies, a subject that requires constant research and updates. In this sense, the objective of the present article was to review studies on the role of wild animals as reservoirs and/or dispersers of etiological age... more

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Our Risk For Infectious Diseases Is Increasing Because of Climate Change

National Center for Emerging and Zoonotic Infectious Diseases (NCEZID) NCEZID, CDC (2018) C_CDC

As the nation’s public health leader, the Centers for Disease Control and Prevention (CDC) is actively engaged in a national effort to protect the public’s health from the harmful effects of climate change. Scientists from CDC’s National Center for Emerging and Zoonotic Infectious Diseases (NC... more

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Elimination of human rabies in Goa, India through an integrated One Health approach

Gibson, A.; Yale, G.; Corfmat, J.; et al. nature communications (2022) CC

Rabies is a devastating and societally important zoonotic disease, which is transmitted principally to humans through the bite of infected dogs. This acute, progressive viral encephalitis has the highest case fatality of any infectious disease and kills tens of thousands of people annually, with chi... more

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Rabies Frequently Asked Questions

National Institute for Communicable Disease NICD (2021) CC

Rabies is a zoonotic, vaccine-preventable viral disease that causes damage to the brain and spinal cord in infected animals and humans. A zoonotic disease is a disease that can be transmitted between animals and humans. Rabies is nearly 100% fatal once symptoms appear.

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“Crafting the mosaic” A framework for resilient surveillance for respiratory viruses of epidemic and pandemic potentia

World Health Organisation (WHO) (2023) C_WHO

It is impossible to address the many complex needs of respiratory virus surveillance with a single surveillance system. Multiple systems, investigations and studies must each be fit-for-purpose to specific priority surveillance objectives, and only together can they provide essential information to ... more

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Public health resource pack for countries experiencing outbreaks of influenza in animals: revised guidance

World Health Organisation (WHO) (2023) C_WHO

This resource pack was developed for the country offices of the World Health Organization and national Public Health institutions, as an overview of the key information needed for advising their Member States in response to questions raised on human health due to influenza outbreaks or detections in... more

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Framework of a national program for preventing and controlling diseases caused by respiratory viruses with epidemic and pandemic potential, Washington, D.C., 2024

Pan American Health organization PAHO; World Health Organization WHO (2024) C_WHO

At the global, national, and regional levels, there are several guidelines and guides regarding the preparedness, prevention, surveillance, and control of diseases caused by respiratory viruses; most initiatives focus on specific virus events or cases. During the coronavirus disease 2019 (COVID-19) ... more

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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

Laboratory testing for Zika virus and dengue virus infections: interim guidance recommended

Laboratory testing for Zika virus and dengue virus infections: interim guidance
recommended