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Laboratory quality management system: Handbook

World Health Organization et al. WHO (2011) C_WHO

"Achieving, maintaining and improving accuracy, timeliness and reliability are major challenges for health laboratories. Countries worldwide committed themselves to build national capacities for the detection of, and response to, public health events of international concern when they decided to eng... more

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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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SAARC Regional Strategy for Control/Elimination of Tuberculosis 2013-2017

SAARC Tuberculosis and HIVAIDS Centre Nepal (2015) C1

The SAARC Member States have more than an estimated 2.0 million TB cases accounting for close to one-third of the total cases of TB in the world. India alone had almost one-fifth of the global disease burden due to TB. India, Pakistan and Bangladesh followed by Afghanistan are the major contributors... more

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GLI Practical Guide to TB Laboratory Strengthening

Global Laboratory Initiative World Health Organization (2017) C_WHO

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WHO/UNAIDS Annual Meeting with pharmaceutic companies and stakeholders

D. K. Mubangizi; M. Stahl; M. Smid; et al. World Health Organization (2016) C_WHO

Session V: Regulatory & quality assurance aspects Update on prequalification of ARVs and regional harmonisation of medicine registration Deusdedit K. Mubangizi Group Lead, Inspections, WHO-PQT E-mail: mubangizid@who.int Acknowledgements: • Matthias Stahl • Milan Smid • Antony Fake ... more

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Swaziland National Implementation Strategy: Improving Health Care Waste Management Systems

Ministry of Health. The Goverment of the Kingdom of Swaziland (2015) C1

Accessed 15th of October 2015

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National Strategic Plan for Tuberculosis Control in Georgia 2016-2020

CCM Georgia (2015) C1

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Multi-sector Nutrition Plan For Accelerated Reduction of Maternal and Child Under-nutrition in Nepal 2013-2017 (Nepali Version)

Government of Nepal, National Planning Commission (2013) C1

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Preventing HIV misdiagnosis: implementation guide

World Health Organization WHO (2024) CC

HIV testing programmes need to ensure that all clients who test for HIV are provided with correct diagnoses. The accuracy of HIV testing is critical to prevent misdiagnosis, as the consequences of giving an incorrect test result can be serious for clients, HIV testing services, HIV programmes and pu... more

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Practical manual on tuberculosis laboratory strengthening, 2022 update

World Health Organisation (WHO) (2023) C_WHO

The Practical manual on laboratory strengthening, 2022 update provides practical guidance on implementation of WHO recommendations and best practices for TB laboratory strengthening. It is an updated version of the GLI Practical Guide to Laboratory Strengthening published in 2017 and provides the la... more

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Multi-sectoral National Action Plan on Antimicrobial Resistance 2017-2027 (Zambia)
recommended

Government of the Republic of Zambia (2018) CC

Zambia has recognised the Public Health threat of antimicrobial resistance and its impact on morbidity and mortality, as well as the subsequent economic consequences. The country has recorded microorganisms which have developed resistance to antimicrobial drugs. Notable among these are; Multidrug Re... more

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National HIV, Hepatitis and STI programme managers meeting for selected asian and pacific island countries

World Health Organization (Western Pacific Region) (2018) C_WHO

Meeting Report 27–30 June 2017 Manila, Philippines

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Target Product Profile (TPP) for the development of improved Cholera rapid diagnostic tests

Global Task Force on Cholera Control (GTFCC) World Health Organisation (WHO) (2017) C_WHO

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WHO Prequalification of Male Circumcision Devices - Product: PrePex, Number: PQMC 0001-001-04

World Health Organization (WHO) World Health Organization (WHO) (2016) C_WHO

Public Report PQMC 0001-001-04 WHO PQMC Public Report November/2016, version 8.0

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Malaria diagnostics technology and market landscape. 3rd edition
recommended

UNITAID World Health Organization (WHO) (2016) C_WHO

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National Operational Plan for Scaling up HIV Viral Load Testing
recommended

Ministry of Health and Social Welfare, National AIDS Control Programme, Tanzania (2015) CC

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Failure to Protect: Syria and the UN Security Council

Global Centre for the Responsibility to Protect (2015)

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Rwanda: HEALTH SECTOR ANNUAL REPORT July 2013-June 2014

Ministry of Health, Rwanda (2014) C2

This report highlights key achievements registered by the Ministry of Health, affiliated institutions, implementing agencies both at central and decentralized levels in 2013-2014. Generally, the Health Sector accomplishments and programs routine data for 2013-2014 confirm that Rwanda maintains its p... more