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Introduction of DNA-based identification and typing methods to public health practitioners for epidemiological investigation of cholera outbreaks

Global Task Force on Cholera Control (GTFCC) World Health Organisation (WHO) (2017) C_WHO

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Comparison of sensitivity and specificity of three diagnostic tests to detect Schistosoma mansoni infections in school children in Mwanza Region, Tanzania

Fuss, A.; H.D. Mazigo; D. Tappe, C.Kasang, A. Mueller (2018) CC

PLoS ONE 13(8): e0202499. https://doi.org/10.1371/journal.pone.0202499 This was a school-based cross-sectional study conducted in 2015 among 305 school children aged 7–16 years from two primary schools located in Ilemela and Magu Districts, north-western Tanzania. Single stool and urine samples w... more

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Guião de Actividades de Apoio Psicossocial e Prevenção Positiva (Moçambique)

Ministério da Saúde (MISAU), Direcção Nacional de Assistência Médica (DNAM) (2015) C1

Este guião tem como objetivos melhorar a qualidade do aconselhamento a doentes com HIV/SIDA, providenciar meios para garantir uma avaliação psicossocial e identificar fatores de risco que contribuem para uma baixa adesão à TARV e estabeceler a ligação entre a unidade sanitária e a comunidade... more

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Evaluation de la prestation des agents de santé à base communautaire - Rapport provisoire

Ministère de la santé - Secrétariat général - Direction général de l'information et des statistiques sanitaires (2013) C2

La présente étude commanditée par l'Organisation mondiale de la santé (OMS) et le Fond Mondial pourra aider à mieux cerner les problèmes que peuvent rencontrer les ASBC dnas la mise en Oeuvre de leurs activités. Elle pourra servir d'élément de base dans la planification des acitivités comm... more

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What are nucleic acid vaccines and how could they be turned against COVID-19?

GAVI (2021) CC

All vaccines work by exposing the body to molecules from the target pathogen to trigger an immune response – but the method of exposure varies. Here’s how DNA and RNA vaccines work.

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COVID-19 Vaccine Acceptance

Compass (2021) CC

Social and behavior change (SBC) professionals have often been tasked to find ways to influence knowledge, attitudes, and practices, about vaccines. Now that the COVID-19 vaccines are becoming available worldwide, renewed emphasis and urgency for SBC efforts arise. To that end, WHO has offered thre... more

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Management of Dead Bodies After Disasters: A Field Manual For First Responders. (Arabic Version)
recommended

Cordner, S.; R. Coninx; J.-J. Kim; et al. PAHOWorld Health Organization; ICRC; IFRC (2016) C_WHO

Second edition. This revised edition incorporates experience gained in recent catastrophes, such as the 2013 Typhoon Haiyan in the Philippines, the 2014/15 Ebola epidemic in West Africa and the 2015 earthquake in Nepal. It also contains a number of annexes, which cover such topics as handling the bo... more

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Do vaccines alter your DNA?

Science in Motion (2021) CC

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Myths & COVID-19 Vaccinations
recommended

Mauder, S.; and P. Reijer (2021) CC

Issue Brief no. 16. 20 Sept 2021. Many studies have shown the effectiveness of vaccination against COVID-19 and that it protects against severe illness. A high vaccination rate is needed to combat the pandemic worldwide. Due to misinformation and myths, there is still a great hesitancy to vaccina... more

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Mythes & COVID-19 Vaccins
recommended

Mauder, S.; and P. Reijer (2021) CC

MEDBOX Dossier no. 16. 28 Sept 2021. De nombreuses études ont montré l'efficacité de la vaccination contre le COVID-19 et le fait qu'elle protège contre les maladies graves. maladie grave. Un taux de vaccination élevé est nécessaire pour combattre la pandémie dans le monde entier. En raiso... more

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The Top COVID-19 Vaccine Myths Spreading Online

Gregory, J. NewsGuard (2021) CC

Scientists and researchers managed to produce vaccines to protect against COVID-19. Vaccine candidates have recently been approved in some countries and are in the approval process in others, yet misinformation about the safety and effects of any future vaccine is already threatening its rollout. In... more

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Laboratory testing for the monkeypox virus
recommended

World Health Organization (WHO) (2022) C_WHO

Any individual that meets the suspected case definition of monkeypox should be offered testing in appropriately equipped laboratories by staff trained in the relevant technical and safety procedures. Confirmation of monkeypox virus infection is based on nucleic acid amplification testing (NAAT), usi... more

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Monkeypox Technical Factsheet

African Union; Africa CDC Centres for Disease Control and Prevention (2022) C1

Monkeypox is a rare viral zoonotic disease caused by a double stranded DNA virus that belongs to the Orthopoxvirus genus of the Poxviridae family.

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Comparison of the Influence of Different Nucleic Acid Extraction Assays on the Sensitivity of Trypanosoma cruzi-Specific Real-Time PCR

Kann, S.; Zabala-Monterroza, W.; García, C. et al. Multidisciplinary Digital Publishing Institute MDPI (2022) CC

For the molecular diagnosis of Chagas disease by real-time PCR (polymerase chain reaction), optimization of diagnostic accuracy is desirable. The detection limit of real-time PCR assays for the diagnosis of Trypanosoma cruzi in human serum is affected by various influences including the choice of th... more

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Pathology of Schistosomiasis

Roy, S. (2022) CC

DNA studies of Egyptian mummies shows evidence of the existence of Schistosomiasis about 5000 years ago. Schistosomiasis is increasing in prevalence, affecting nearly 10% of the world’s population and ranking second only to malaria as a cause of morbidity & mortality. Schistosoma haematobium are... more

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Ancient pathogens provide a window into health and well-being

Lewis, C. Jr., Akinyi, M., DeWitte, S. et al. Proceedings of the National Academy of Sciences PNAS (2022) CC

This perspective draws on the record of ancient pathogengenomes and microbiomes illuminating patterns of infectious disease over the course of the Holocene in order toaddress the following question. How did major changes inliving circumstances involving the transition to and intensification of farmi... more

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Guidelines for the prevention, diagnosis, care and treatment for people with chronic hepatitis B infection (March 2024)

World Health Organization WHO (2024) C_WHO

Hepatitis B (HBV) infection is a major public health problem and cause of chronic liver disease. The 2024 HBV guidelines provide updated evidence-informed recommendations on key priority topics. These include expanded and simplified treatment criteria for adults but now also for adolescents; expa... more

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Factsheet – 5 facts about alcohol and cancer

World Health Organization WHO (2021) CC

This factsheet provides five important facts for policy makers, health professionals and the general public about the links between alcohol consumption and a range of cancer types. This affects not only people who drink alcohol but also their families, friends and communities. - Alcohol causes at l... more

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Mpox Technical Factsheet

Africa CDC (2024) CC

Mpox is a zoonotic disease caused by a double-stranded DNA virus that belongs to the Orthopoxvirus genus of the Poxviridae family. The disease presents with symptoms similar to smallpox but with a lesser severity. It was first discovered in 1958 when two outbreaks of a poxlike disease occurred in co... more

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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

Management of Dead Bodies After Disasters: A Field Manual For First Responders. (Arabic Version) recommended

Myths & COVID-19 Vaccinations recommended

Mythes & COVID-19 Vaccins recommended

Laboratory testing for the monkeypox virus recommended

Management of Dead Bodies After Disasters: A Field Manual For First Responders. (Arabic Version)
recommended

Myths & COVID-19 Vaccinations
recommended

Mythes & COVID-19 Vaccins
recommended

Laboratory testing for the monkeypox virus
recommended