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WHO has updated its guidelines for COVID-19 therapeutics, with revised recommendations for patients with non-severe COVID-
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19. This is the 13th update to these guidelines.
Updated risk rates for hospital admission in patients with non-severe COVID-19
The guidance includes updated risk rates for hospital admission in patients with non-severe COVID-19.
The current COVID-19 virus variants tend to cause less severe disease while immunity levels are higher due to vaccination, leading to lower risks of severe illness and death for most patients.
This update includes new baseline risk estimates for hospital admission in patients with non-severe COVID-19. The new ‘moderate risk’ category now includes people previously considered to be high risk including older people and/or those with chronic conditions, disabilities, and comorbidities of chronic disease. The updated risk estimates will assist healthcare professionals to identify individuals at high, moderate or low risk of hospital admission, and to tailor treatment according to WHO guidelines:
**High: **People who are immunosuppressed remain at higher risk if they contract COVID-19, with an estimated hospitalization rate of 6%.
**Moderate: **People over 65 years old, those with conditions like obesity, diabetes and/or chronic conditions including chronic obstructive pulmonary disease, kidney or liver disease, cancer, people with disabilities and those with comorbidities of chronic disease are at moderate risk, with an estimated hospitalization rate of 3%.
Low: Those who are not in the high or moderate risk categories are at low risk of hospitalization (0.5%). Most people are low risk.
Review of COVID-19 treatments for people with non-severe COVID-19
WHO continues to strongly recommend nirmatrelvir-ritonavir (also known by its brand name ‘Paxlovid’) for people at high-risk and moderate risk of hospitalization. The recommendations state that nirmatrelvir-ritonavir is considered the best choice for most eligible patients, given its therapeutic benefits, ease of administration and fewer concerns about potential harms. Nirmatrelvir-ritonavir was first recommended by WHO in April 2022.
If nirmatrelvir-ritonavir is not available to patients at high-risk of hospitalization, WHO suggests the use of molnupiravir or remdesivir instead.
WHO suggests against the use of molnupiravir and remdesivir for patients at moderate risk, judging the potential harms to outweigh the limited benefits in patients at moderate risk of hospital admission.
For people at low risk of hospitalization, WHO does not recommend any antiviral therapy. Symptoms like fever and pain can continue to be managed with analgesics like paracetamol.
WHO also recommends against use of a new antiviral (VV116) for patients, except in clinical trials.
The update also includes a strong recommendation against the use of ivermectin for patients with non-severe COVID-19. WHO continues to advise that in patients with severe or critical COVID-19, ivermectin should only be used in clinical trials.
more
A country’s ability to manage a crisis depends on its level of resilience. Efforts are made to clarify the concept of health system resilience, but its operationalisation remains little studied. In the present research, we described the capacity of the local healthcare system in the Islamic Republ
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ic of Mauritania, in West Africa, to cope with the COVID-19 pandemic.
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Global investments in pandemic preparedness and COVID-19: development assistance and domestic spending on health between 1990 and 2026
Global Burden of Disease 2021 Health Financing Collaborator Network
The Lancet Glob Health
(2023)
C2
The COVID-19 pandemic highlighted gaps in health surveillance systems, disease prevention, and treatment globally. Among the many factors that might have led to these gaps is the issue of the financ
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ing of national health systems, especially in low-income and middle-income countries (LMICs), as well as a robust global system for pandemic preparedness.
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This article analyzes the impact of the COVID-19 pandemic on foreign aid. Using examples from Canadian foreign aid, it argues that, despite the terrible toll it is exacting, the crisis has accelerat
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ed some significant positive pre-existing trends, both by destabilizing the perception of aid as flowing essentially from the Global North to Global South and by reinforcing awareness of the importance of joint efforts for global public goods and humanitarian assistance, as well as debt relief. However, it has also reinforced potentially harmful self-interested justifications for aid, which could align assistance more with donors’ priorities than the needs of the poor
more
This article analyzes the impact of the COVID-19 pandemic on foreign aid.
Does Diabetes make someone vulnerable to getting COVID-19:
People with Diabetes are not more likely to get the virus compared to the general public.
However, if they contact
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CoVID-19, people with diabetes are more likely to have serious complications and become seriously ill from COVID-19, than those who do not have diabetes.
If a person with diabetes gets COVID 19, he is more vulnerable to severe form of COVID-19 and is more likely to die than those without diabetes.
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ARE PEOPLE WITH DIABETES MORE LIKELY TO GET COVID-19? People with diabetes are more likely to become seriously ill from COVID-
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19, than those who do not have diabetes. Unfortunately, persons with diabetes who get COVID-19 are more likely to die than those without diabetes.
more
ARE PEOPLE WITH DIABETES MORE LIKELY TO GET COVID-19?
• People with diabetes are more likely to become seriously ill from COVID-
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19, than those who do not have diabetes.
• Unfortunately, persons with diabetes who get COVID-19 are more likely to die than those without diabetes.
more
ARE PEOPLE WITH DIABETES MORE LIKELY TO GET COVID-19?
• People with diabetes are more likely to become seriously ill from COVID-
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19, than those who do not have diabetes.
• Unfortunately, persons with diabetes who get COVID-19 are more likely to die than those without diabetes.
more
In 2018 the Astana Declaration reaffirmed a global commitment to PHC as a cornerstone of sustainable health systems for accelerated progress on universal health coverage (UHC) (1). The vision for PHC in the 21st century is for a wholeof-government and whole-of-society approach to health that combine
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s: 1) multisectoral policy and action; 2) empowered people and communities; and 3) primary care and essential public health functions as the core of integrated health service. Signatories, including Nigeria, were urged to implement the vision and commitments of the Declaration according to their national contexts. This case study examines Nigeria’s response to COVID-19 from a PHC perspective between March 2020 and mid-2021.
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Action Plan for Implementation of Recommendations from the Evaluation of PAHO's Response to COVID-19
An external team evaluated PAHO’s response to COVID-19 to provide an independent assessment of the Pan American Sanitary Bureau’s (PASB) performance regarding preparedness for and response to th
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e COVID-19 pandemic. The evaluations’ final report culminates with eight recommendations for actions to future response to health emergencies. The final report of EPRC culminates with eight evidence-based recommendations of actions to strengthen future pandemic responses, while building a resilient recovery in the Region. The recommendations by the external team focus on PAHO’s governance and management, on specialized regional mechanisms, diversified funding models, and use of new technologies, among others.
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The coronavirus disease (COVID-19) pandemic exacerbated pre-existing inequalities in the treatment and care of noncommunicable diseases (NCDs). This report examines the effect of the
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COVID-19 pandemic on access to NCD medicines, and the policies and strategies implemented by countries and health systems to anticipate and mitigate stresses across NCD medicine supply chains. The full range of upstream and downstream impacts are investigated, including: manufacturing; procurement, importation and last mile delivery; patient-level effects through affordability and availability; and the effects on NCD medicine availability by category of disease. The report culminates in recommended actions and interventions for key stakeholders in the NCD pharmaceutical supply chain, including governments, regulatory authorities, manufacturers and the private sector; as well as directions for future research for improving access and supply chain access resilience.
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"Tackling Noncommunicable Diseases (NCDs), risk factors and mental health during the time of COVID-19" is a series of high-level strategic discussions on transforming the approach to noncommunicable
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diseases, its risk factors and mental health as a result of the pandemic in terms of strengthening health systems and services, responding to emergencies, investing to transform the NCD, RF and MH agenda, optimizing partnerships, among others, with a focus on big picture thought leadership.
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As Uganda builds back from the COVID-19 shock, the Ugandan government is strengthening its commitment to a more gender-inclusive and sustainable economy. This report supports these efforts by descri
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bing the gendered impacts of COVID-19 and provides recommendations for Ugandan policy makers and World Bank Group operations to ensure women’s participation in an inclusive and sustainable recovery. It presents gender-disaggregated data from three main sources: high-frequency phone surveys that track the impacts of the COVID-19 shock: one of Ugandan nationals conducted in June and one of refugees conducted in November 2020; interviews with 28 representatives of government institutions, development partners, and women’s organizations in Kampala and in rural areas; and a review of relevant policy and gray literature on climate change, the green economy, and women’s economic empowerment.
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The RTA covered UNICEF’s response to COVID-19 from March 2020 – when WHO declared the disease a pandemic – until January 2021. Further, the RTA applied a broad and cross-cutting lens to all 21
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UNICEF county offices across the region, focusing on six case study countries: Kenya, Madagascar, Namibia, Somalia, South Africa and Uganda.
In addition to a Regional Analysis Report, the RTA produced six deep-dive reports with findings and lessons specific to the six case study countries mentioned above – all of which can be accessed through the drop-down listing on this page.
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This case study uses the Astana Primary Health Care (PHC) framework to explore the impact of the 2020–21 pandemic on primary health care in Kenya. While the pandemic exposed systemic challenges, such as limited testing capacity, an inadequate supply of PPE, and weak social protection, Kenya's heal
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th system also demonstrated notable adaptability. The response was largely hospital-centred, with PHC playing a secondary role. Nevertheless, innovations emerged on both the provider and consumer sides to maintain service delivery and access. The study emphasises the importance of building on these experiences to enhance emergency preparedness and develop a more robust and integrated health system.
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There is widespread recognition of the growing threat of infectious disease epidemics and pandemics spreading across countries or continents—especially following the recent Ebola and COVID-19 pan
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demics. Vulnerable groups (including children, older adults, ethnic minorities and other at-risk groups) have disproportionately borne the brunt of significant health, social, and economic effects of these epidemics and pandemics, with varying degrees of support received depending on the context. While many argue that communities should or need to play a critical role in supporting and leading preparedness and response efforts, work still needs to be done to engage them effectively. In many instances, modes of engagement with communities—especially by state authorities–have come too late, often as an afterthought are not adequately thought through and have undermined public trust in and support for, disease prevention and control measures
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