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In-depth: What should behaviour change efforts look like in the PrEP era?

Molelekwa, T. Spotlight (2022) CC
what lessons can we take from the last few decades of health behaviour change efforts as we enter the era of HIV prevention pills, rings and injections?
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Guidance on handling interruptions in antiretroviral treatment due to HIV service disruptions, drug shortages, or stockouts
recommended

World Health Organization WHO (2025) C_WHO
Questions and answers. A key priority is preventing the interruption of current HIV treatment and prevention medicines. This Q&A outlines advice when this is not possible. Available in Arabic, Chinese, English, French, Portuguese, Russian and Spanish
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WHO guidelines on the management of advanced HIV disease
recommended

World Health Organization WHO (2025) C_WHO
These 2025 guidelines respond to the need for better approaches to identify advanced HIV disease, improve the poor outcomes of people living with HIV being discharged from hospital and provide updated guidance for treatment for Kaposi’s sarcoma through evidence-informed recommendations. The public ... more
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Adolescent HIV treatment

United Nations International Children's Emergency Fund UNICEF (2025) C_UNICEF
About six in ten adolescents 10-19 years of age living with HIV are on antiretroviral medications
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HIV - Paediatric care and treatment

United Nations International Children's Emergency Fund UNICEF (2025) C_UNICEF
Slightly more than half of children under 15 years of age living with HIV are on antiretroviral medications
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Guidelines for the Use of Antiretroviral Agents in Pediatric HIV Infection
recommended

Panel on Antiretroviral Therapy and Medical Management of Children Living with HIV (2025) C1
The information in the brief version is excerpted directly from the full-text guidelines. The brief version is a compilation of the tables and boxed recommendations. The guidelines were updated to comply with Executive Orders. You can download the full guidelines, charts and recommendations
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HIV in Adults: 2024 Recommendations of the International Antiviral Society–USA Panel

Gandhi RT, Landovitz RJ, Sax PE, et al. (2024) CC
JAMA. 2025;333(7):609–628. doi:10.1001/jama.2024.24543
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Time to HIV viral rebound and frequency of post-treatment control after analytical interruption of antiretroviral therapy: an individual data-based meta-analysis of 24 prospective studies

Gunst, J.D.; et al. (2025) CC
Nature communications, 16, 906 (2025). https://doi.org/10.1038/s41467-025-56116-1
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Q&A on the impact of the interruption of treatment for people living with HIV

UNAIDS (2025) CC
Recent suspensions and reductions in official development assistance (ODA) have posed significant challenges to HIV programme continuity in several countries. These funding disruptions have impacted people living with HIV and other vulnerable populations who rely on these essential services, like a ... more
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Dosing of LOPINAVIR/RITONAVIR for Children 2020

Ministry of Health, South Africa (2020) CC
Dosing of LPV/r by formulation & dose modification (RTV super-boosting/double-dose LPV/r) for children receiving rifampicin-containing TB treatment. Chart
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Antiretroviral Dosing Chart for Children

Ministry of Health, South Africa (2023) CC
Annexure 6 National Guidelines South Africa 2023
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Dolutegravir resistance very rare after a switch - even with detectable HIV

AIDSmap (2024) CC
The emergence of high-level dolutegravir resistance was extremely rare in people switched to first-line dolutegravir-based treatment in Zambia and Malawi, a large prospective study has found.
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What can modelling tell us about the scale-up of lenacapavir for pre-exposure prophylaxis?

UNAIDS (2025) C_WHO
Modelling shows that it will be essential to complement lenacapavir with additional prevention options, testing and treatment. See “Meeting reports” at https://www.unaids.org/en/resources/publications/all for a description of models and tools to estimate potential impact and quantifications requ ... more
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WHO/HIVRESNET HIV drug resistance - laboratory operational framework

World Health Organization WHO (2020) C_WHO
The aim of the operational framework is to ensure 1) accurate collection, handling, shipment and storage of specimens collected in countries implementing HIV drug resistance surveillance; and 2) the availability of quality-assured HIV genotyping laboratory services producing comparable and reliable ... more
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Malawi - HIV Country Profile 2024

World Health Organization WHO (2024) C_WHO
Demographic and socioeconomic data Progress towards HIV testing and treatment cascade targets by 2025 (2023) Health sector cascade (2023) Estimated number of people newly infected with HIV
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Effectiveness and safety of dolutegravir and raltegravir for treating children and adolescents living with HIV: a systematic review

ownsend CL, O'Rourke J, Milanzi E, et al. (2022)
J Int AIDS Soc. 2022 Nov;25(11):e25970. doi: 10.1002/jia2.25970. PMID: 36377082; PMCID: PMC9663860. These reassuring findings suggest that dolutegravir and raltegravir are effective and safe as preferred regimens in children and adolescents living with HIV. With the rollout of dolutegravir in paedia ... more
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Technical update on treatment optimization: use of tenofovir disoproxil fumarate in HIV-infected children and adolescents aged 2–18 years: a public health perspective

World Health Organization (2012)
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Technical update on treatment optimization: use of efavirenz during pregnancy: a public health perspective

World Health Organization (2012) C_WHO
1.HIV infections – drug therapy. 2.Anti-HIV agents – adverse effects. 3.Anti-retroviral agents. 4.Benzoxazines – adverse effects. 5.Pregnancy. 6.Disease transmission, Vertical - prevention and control. 7.Treatment outcome. I.World Health Organization
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Clinical Guidelines for Antiretroviral Therapy Management for Displaced Populations Southern Africa
recommended

Southern African HIV Clinicians Society UNHCR (2007)
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Guidelines for the programmatic management of drug-resistant tuberculosis

World Health Organization (2011) C_WHO
This 2011 update of Guidelines for the programmatic management of drug-resistant tuberculosis is intended as a tool for use by public health professionals working in response to the Sixty-second World Health Assembly’s resolution on prevention and control of multidrug-resistant tuberculosis and e ... more