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Publication Years
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Category
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331
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Toolboxes
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Of the 50 antibiotics in the pipeline, 32 target WHO priority pathogens but the majority have only limited benefits when compared to existing antibiotics. Two of these are active against the multi-drug resistant Gram-negative bacteria, which are spreading rapidly and require urgent solutions.
Gr
...
am-negative bacteria, such as Klebsiella pneumoniae and Escherichia coli, can cause severe and often deadly infections that pose a particular threat for people with weak or not yet fully developed immune systems, including newborns, ageing populations, people undergoing surgery and cancer treatment.
The report highlights a worrying gap in activity against the highly resistant NDM-1 (New Delhi metallo-beta-lactamase 1), with only three antibiotics in the pipeline. NDM-1 makes bacteria resistant to a broad range of antibiotics, including those from the carbapenem family, which today are the last line of defence against antibiotic-resistant bacterial infections.
more
Las infecciones de transmisión sexual (ITS) constituyen un importante problema de salud pública en todo el mundo, que afecta a la calidad de vida y se acompaña de importantes niveles de morbilidad y mortalidad. Estas infecciones influyen directamente en la salud infantil y reproductiva porque tra
...
en consigo infertilidad, cánceres y complicaciones del embarazo. También tienen una influencia indirecta porque facilitan la transmisión por vía sexual del virus de la inmunodeficiencia humana (VIH), pesando así igualmente en la economía de los países y las personas. Cada día, más de un millón de personas contraen una infección de transmisión sexual. Se calcula que en 2012 hubo en el mundo 357 millones de nuevos casos de ITS curables (blenorragia, clamidiasis, sífilis o tricomoniasis) que afectaron a adultos de entre 15 y 49 años de edad, entre ellos 5,6 millones de casos de sífilis. El número de casos prevalentes de sífilis asciende, según las estimaciones, a unos 18 millones.
more
Ramped-up cancer services could save 7 million lives over the next decade—and addressing huge service gaps between rich and poor countries is key to success, according to this report.
In 2019, over 90% of high-income countries reported that comprehensive cancer treatment services were available
...
through the public health system, compared to fewer than 15% of low-income countries, according to WHO.
But poorer countries can make substantial strides with a universal health coverage approach and use of the latest science to meet their particular needs.
The report lays out proven ways to prevent new cancer cases without breaking the bank, including tobacco-control measures and vaccines that protect against common cancers.
more
Accessed Febr. 6, 2020
Accessed Febr. 6 ,2020
accessed Febr. 6, 2020
Accessed Febr. 6, 2020
Accessed Febr. 6, 2020
Accessed Febr. 6, 2020
Guidelines for the management of pregnant and breastfeeding women in the context of Ebola virus disease
recommended
To save the lives of mothers and their babies, mitigate complications, and limit the spread of disease, it is critical that recommendations are made on the prevention, treatment, and surveillance of women who are exposed to EVD, acquire EVD during pregnancy or breastfeeding, or survive EVD with ongo
...
ing pregnancies. These guidelines are the first to provide such recommendations.
more
Pregnancy often results in exclusion from clinical trials of antiretroviral (ARV) drugs, resulting in limited data on pharmacokinetics (PK), drug safety, and the efficacy of new ARV drugs in pregnancy and lactation. However, pregnancy, lactation, or the potential for pregnancy should not preclude th
...
e use of drug regimens that would be chosen for people who are not pregnant, unless adequate drug levels are not likely to be attained in pregnancy or known adverse effects outweigh potential benefits
more
The following protocol has been designed to investigate the First Few X cases (FFX) and their close contacts. It is envisioned that the FFX 2019-nCoV investigation will be conducted across several countries or sites with geographical and demographical diversity. Using a standardized protocol such a
...
s the protocol provided here, epidemiological exposure data and biological samples can be systematically collected and shared rapidly in a format that can be easily aggregated, tabulated and analyzed across many different settings globally for timely estimates of 2019-nCoV infection severity and transmissibility, as well as to inform public health responses and policy decisions. This is particularly important in the context of a novel respiratory pathogen, such as 2019-nCoV
more
Household transmission investigation protocol for 2019-novel coronavirus (2019-nCoV) infection
recommended
The household transmission investigation is a case-ascertained prospective study of all identified household contacts of a laboratory confirmed 2019-nCoV infection (see 2.2 Study population). It is intended to provide rapid and early information on the clinical, epidemiological and virological chara
...
cteristics of 2019-nCoV.
There are three primary objectives of this household transmission study:
To better understand the extent of transmission within a household by estimating the secondary infection rate for household contacts at an individual level, and factors associated with any variation in the secondary infection risk.
To characterize secondary cases including the range of clinical presentation, risk factors for infection, and the extent and fraction of asymptomatic infections.
To characterize serologic response following confirmed 2019-nCoV infection (highly encouraged, but optional depending on laboratory capacity and resources)
more
16-24 February 2020
Chapter 1 of the WHO manual for male circumcision as an HIV prevention strategy
provides an overview of how medical male circumcision (VMMC) can reduce the risk of female-to-male HIV transmission. It explains that VMMC is an effective and safe risk-reduction method that, according to three randomiz
...
ed controlled trials, reduces HIV acquisition by approximately 60%. The chapter highlights that VMMC should be offered as part of a combination prevention approach, alongside other strategies like safer sex education and condom use, to address concerns about potential behavioral changes.
more
Report of the WHO Technical Advisory Group | 12 August 2016 | Geneva, Switzerland
A Guide to the Application of the WHO Multimodal Hand HygieneImprovement Strategy and the “My Five Moments for Hand Hygiene”Αpproach
Community Health Impact Coalition members & colleagues from across the world are sharing COVID-19 explainers, internal policies, clinical protocols, & more live
