Ministry of Health and Social Welfare, National AIDS Control Programme, Tanzania
15
UNICEF
15
Stop TB Partnership
14
Ministry of Health and Social Welfare, Tanzania
13
University Teaching Hospital, et al.
12
Ministry of Health
11
Dept. of Health, Republic of South Africa
9
Ministry of Health, Malawi
8
Ministry of Health, Zambia
7
World Health Organization Europe
7
END TB
6
International Union Against Tuberculosis and Lung Disease
6
Ministry of Health and Social Services (MOHSS)
6
National AIDS Control Organization (NACO), Ministry of Health and Family Welfare, Government of India
6
The Global Fund
6
UNFPA
6
UNOPS
6
Federal Ministry of Health, Nigeria
5
Government of Malawi, Ministry of Health
5
ICF International
5
Ministry of Health Ghana
5
Ministry of Health, Zambia, et al.
5
United States Agency for International Development (USAID)
5
University Teaching Hospital,
5
World Health Organization (Europe)
5
BioMed Central
4
Disability, CBR & Inclusive Development Journal (DCIDJ)
4
European Centre for Disease Prevention and Control
4
Ministry of Health and Social Welfare, The United Republic of Tanzania
4
Ministry of Health Uganda
4
Ministry of Health, Ghana
4
Ministry of Health, Tanzania
4
National AIDS
4
PEPFAR
4
PLOS One
4
Brot für die Welt
3
C. Daniels
3
C. Smyth, et al.
3
Centers for Disease Control and Prevention
3
European Union
3
Federal Ministry of Health, Ethiopia
3
FG Consulting Group
3
fhi360
3
Ghana Health Service
3
Government of Tanzania
3
Lesley Odendal
3
Ministry of Health & Ministry of Local Government, Gabarone, Botswana
3
Ministry of Health and Family Welfare, Government of India
3
Ministry of Health and Social Welfare, Liberia
3
Ministry of Health, Republic of Uganda
3
Ministry of Health, Rwanda
3
Ministry of Health, Uganda
3
National HIV
3
Oxfam
3
PAHO Pan American Health Organization, Enfant du Monde
3
Save the children
3
SIAPS
3
The International Federation of Anti-Leprosy Associations (ILEP)
3
Three Millennium Development Goal Fund (3MDG)
3
UNAIDS (Joint United Nations Programme on HIV/AIDS)
3
UNHCR
3
World Health Organisation (WHO)
3
World Health Organization, Stop TB Partnership
3
World Health Organization, Regional Office for South-East Asia
3
AIDSFree
2
Avert
2
BMC Infectious Diseases
2
BMZ
2
C. Daniels, et al.
2
Catholic Relief Services
2
CII Confederation of Indian Industry
2
Department of Health (DOH)
2
Department of Health (DOH) Philippines
2
Dr. V. R. Kandula
2
Engender Health Society (Improving Women's Health Worldwide)
2
etc al.
2
European Monitoring Centre for Drugs and Drug Addiction
2
European Union EU
2
F. Saini
2
Family Health International FHI
2
Federal Democratic Republic of Ethiopia, Ministry of Health
2
Federal Ministry of Health, Dept. of Public Health, National HIV
2
Food, Medicine and Health care Administration and Control Authority of Ethiopia (FMHACA)
2
G. Venugopal
2
GIZ
2
GiZ Deutsche Gesellschaft für Internationale Zusammenarbeit
2
Government of India, Ministry of Health and Family Welfare, National AIDS Control Organisation (NACO)
2
Government of Sierra Leone, Ministry of Health and Sanitation
2
Health System Trust
2
HEART
2
Hesperian
2
Hesperian Health Guides
2
Human Rights Watch
2
IACAPAP
2
M. Ristola
2
M. Smelyanskaya, J. Duncan (The Focus Group Consulting)
2
Malaria Consortium
2
Medical Peace Work
2
Ministry of Health & Social Welfare India
2
Ministry of Health and Family Welfare Government of India
2
Ministry of Health and Family Welfare Government of the People's Republic of Bangladesh
2
Ministry of Health and Sanitation Sierra Leone
2
Ministry of Health Ethiopia
2
Ministry of Health, Republic of Kenya
2
NACO
2
NADMO Ghana
2
National Agency for the Control of AIDS (NACA)
2
National AIDS Control Organisation (NACO), Government of India
2
National AIDS Control Organisation (NACO), Ministry of Health & Family Welfare, Government of India
2
National AIDS Control Organisation (NACO), Ministry of Health and Family Welfare (MOHFW), Government of India
2
National AIDS Control Programme (NACP) & Reproductive and Child Health Section
2
National Center for HIV
2
National Health Mission
2
Pan American Health Organization
2
Pan American Journal of Public Health
2
Pata
2
Pata Pata Pata
2
Population Foundation of India
2
PubMed.gov
2
Republic of Kenya, Ministry of Health
2
SAARC Tuberculosis and HIV
2
Sida
2
Tanzania Diabetes Association
2
The Brazilian Journal of Infectious Diseases
2
The International Union Against Tuberculosis and Lung Disease
2
The Republic of the Union of Myanmar, Ministry of Health and Sports
2
UNDP
2
UNIFEM
2
United Nations Children's Fund (UNICEF)
2
USAID, AIDS Free Nigeria, et al.
2
WHO and DOH Philippines
2
World Food Programme (WFP)
2
World Health Organization, Europe
2
World Health Organization, International Confederation of Midwives
2
World Health Organization, Regional Office for Africa
2
390: 898&ndash
1
4 Children
1
912
1
A. A. Olashore
1
A. Abdul-Quader
1
A. Abdul-Quader, M. Berry, T. Bingham
1
A. Alebel
1
A. August Burns, Sandy Nieman, Elena Metcalf, Ronnie Lovich, Jane Maxwell, Katharine Shapiro
1
A. Benzacar
1
A. Boltaev
1
A. Brown
1
A. E. Kendall
1
A. E. Miranda
1
A. G. Lentoor
1
A. Gebrie
1
A. Gupta
1
A. J. Prendergas
1
A. Landry, et al.
1
A. Lycett
1
A. M. Tavares
1
A. Miarinjara and S.Boye
1
A. Ojoo, B. Amugune et al.
1
A. Piubello
1
A. Roy, M. Eisenhut, R. . Harris, et al.
1
A. Strode
1
A. Teltschik
1
A. Turkova
1
A. Volokha
1
A. Welbourn
1
Aaron M Kipp, Margaret Maimbolwa, Marie A Brault et al.
1
Ablo Prudence Wachinou, Serge Ade, Gildas Agodokpessi, Berenice Awanou, Dissou Affolabi, Wilfried Bekou, Marius Esse, Gabriel Ade, Severin Anagonou, Anthony D. Harries,1Programme National contre la Tuberculose (PNT), Cotonou, Bénin
1
Academy for Educational Development
1
Access to Medicine Foundation
1
ACF International
1
ACTafrica, HNP
1
Addis Ababa City Administration Health Bureau
1
Aditya Vyas
1
Advocates for action
1
AECT
1
AFEW
1
AFMC Resource Group
1
AIDS & TB Programme
1
AIDS Action
1
Aidsmap
1
Ajit Pradhan, Pradeep Poudel, Deborah Thomas, Sarah Barnett
1
Alan J Flisher
1
Alexander Butchart, David Brown, Andrew Wilson, and Christopher Mikton
1
Alister C. Munthali
1
All-Ukraine Network of PLWH
1
Alliance
1
Allied Publishers Private LTD.
1
ALNAP
1
ALNAP, Provention Consortium
1
Alzheimer's Association
1
Amanda Mattsson
1
American Academy of Paediatrics
1
AMSHeR (American Men for sexual Health & Rights)
1
and D.V.Havlir
1
and ICF
1
Angelo Barbato, Martine Vallarino, Filippo Rapisarda, et al.
1
APN+
1
ARASA (AIDS & Rights Alliance for Southern Africa)
1
Arkangelo Ali Association
1
Arne H Eide & Bhekie Jele
1
Asia Pacific Observatory on Health Systems and Policies
1
Astle. B.
1
AUNAIDS
1
B-Lajoie,MR. O. Drouin,G. Bartlett, et al.
1
B. Durovnia
1
B. Frank‐Hatitchki: O. Ogunwobi
1
B. H. Singer (Princeton University)
1
B. Hauer, R. Loddenkemper, A. Detjen, et al.
1
B. James, Ph.D.
1
B. Killingo
1
B. Mboya, P. Maro, J. Gulaka et al.
1
B. Tesfaye
1
BardenO'Fallon J, Barry MA, Brodish P, et al.
1
Basic Needs Ghana
1
Bayerisches Landesamt für Gesundheit und Lebensmittelsicherheit
1
Becher, H.
1
Benjamin O Alli [et al.]
1
Bethesda, MD: Health Finance & Governance Project, Abt Associates Inc.
1
Beverley Snell
1
Bhattacharya A, et al.
1
Blazé, M., Bowen, G., Godfrey-Magee, A., Lewis, D., et al.
1
Bloomberg Philanthropic
1
BMC Health Services Research
1
BMC Public Health (BioMed Central)
1
bmj
1
BMJ Journals
1
Bonelli, R.
1
BooMed Central
1
Braitstein, Paula et al.
1
British HIV Association
1
BUKO Pharma-Kampagne
1
Butterworth Heinemann
1
by Mark Nunn, Annalies Borrel, Allison deFranco et al.
1
C. Beecroft
1
C. F. Bessa, G. N. lazo, G. V. Sauret
1
C. Hamelmann
1
C. J. Berg
1
C. Leopold
1
C. Pettitt-Schieber, M. Owen, et al.
1
C.A.Faerron-Guzman
1
Calverton, Maryland, USA: ICF International.
1
Cambodian Insittute for Cooperation and Peace
1
Casa
1
Catriona Waddington, Abebe Alebachew and Jarl Chabot
1
CCM Georgia
1
CDS
1
Centers for Disease Control and Prevention , World Health Organization
1
Centers for Disease Control and Prevention , World Health Organization WHO
1
Centers for Disease Control and Prevention CDC
1
Centers for Diseases Control and Prevention
1
Central Statistical Agency [Ethiopia] and ICF International
1
Central TB Division Ministry of Health and Family Welfare, Government of India
1
Central TB Division, Directorate General of Health Services, Ministry of Health & Family Welfare, Nirman Bhavan
1
Centre for Health & Infectious Disease Research
1
Cepuch, C.
1
Cerebral Palsy Association (Eastern Cape)
1
Chaitra Gopalappa, John Stover & Carel Pretorius
1
Challenge TB
1
Chana, R
1
Charles B. Nemeroff
1
Child and Adolescent Psychiatry and Mental Health
1
Child Health Division, Ministry of Health and Social Welfare, Government of India
1
Children & AIDS
1
Christian Connections for International Health (CCIH)
1
Christoffel Blinden Mission (CBM)
1
Christopher Flower
1
Christoplos, I. and Dillon, N. with Bonino, F.
1
CIDRAP
1
CIES IUL
1
Clare Gilbert
1
Clinical Infectious Diseases
1
COC Netherlands
1
Colette van Hees and Ben Naafs
1
Community Development Medicinal Unit
1
Community Eye Health
1
Congressional Research Service
1
Consortium for Universities for Global Health
1
Constella Futures
1
Cooreman, E.A.
1
Cordaid
1
Cristina Otero Garcia
1
CTIF, IAEA, PAHO, WHO
1
Currier, J.S.
1
D. A. Enarson, S. M. Kennedy, D. L. Miller, et al.
1
D. Breuer
1
D. H. Mulligan,
1
D. Jones and Li Webster
1
D. Maradiaga
1
D. P. Chin, C. L. Hanson
1
D. Richardson
1
D. Stuckler, S. Basu, M. McKee, et al.
1
D. van der Veur
1
D. Wolfe
1
Dall, C.
1
Daniel Kojo Arhinful
1
Daniel Perlman, Bertha Pooley, Alejandra Villafuerte,
1
DATER House
1
De Neve. J.-E.
1
Denis Mubiru, Robert Byabasheija, John Baptist Bwanika, et al.
1
Depar tment of Health, National Center for Disease Prevention and Control
1
Departement of Health, Philippines
1
Department of Health
1
Department of Health & Human Services
1
Department of health and human services
1
Department of Health Research Ministry of Health & Family Welfare
1
Department of Health, Comic Relief and the Big Lottery Fund
1
Department of Health, Province of Kwazulu-Natal
1
Department of Health, Republic of South Africa
1
Department of Planning and Health Information, Ministry of Health Cambodia
1
Department: Social Department Republic of South Africa
1
Dept. of HIV and AIDS
1
Deutsche Gesellschaft fü
1
DHS
1
Diana Beck, Frances Ganges, Susan Goldman, Phyllis Long
1
DIFÄM
1
Directorate General of Health Services , Ministry of Health & Family Welfare, Government of India
1
Division of Reproductive Health Ministry of Public Health and Sanitation, Kenya
1
Dominique Morel, and Clara Hagens
1
Don Gorman and Wendy Cross
1
Doug Reeler, Akke Schuurmans, Jeroen Overweel
1
Dr. Bin Bishr, A
1
Dr. Joseph Sitienei OGW
1
Dr. Martin Sirengo
1
Drug Administration and Control Authority of Ethiopia , et al.
1
Durden E.
1
DZK
1
E van‘t Hof, P Cuijpers, W Waheed, DJ Stein
1
E. Abrams
1
E. Chiappini
1
E. Restoy
1
E. Venturini
1
E. Whyle
1
E.Bernard
1
Eaton, Jeffrey W.
1
EBW Healthcare
1
echo.net
1
Economic and Political Weekly
1
Edward O'Neil Jr
1
ehra (eurasian harm reduction association)
1
Ejembi, Clara Ladi, Tukur Dahiru, and Alhaji A. Aliyu
London School of Hygiene and Tropical Medicine (LSHTM)
1
Lucinda Ramos
1
Lunds Universitet
1
Lynn Bennett, Dilli Ram Dahal and Pav Govindasamy
1
M. Berry
1
M. Dara, C. D. Acosta, M. V. S. Vinklers Melchers, et al.
1
M. Djibuti
1
M. Doara, D. Choroliani, P. de Colombani
1
M. Gogia
1
M. Lewis
1
M. Mansfeld
1
M. Mireku,M. Kiruki, R. McCollum, et al.
1
M. Munyeme and S. Malama
1
M. R. Jordan
1
M. Schneider
1
M. Sologashvili
1
M. van der Boom, S. Talevski
1
M. Vitoria
1
M.-A. LeBlanc
1
M.-R. B-Lajoie
1
M.Gumede
1
M.Revishvili
1
Mac-Seing, M.
1
MacQuarrie, K.L.
1
Madhukar Pai
1
Malteser International
1
Management Sciences for Health
1
Manju Vatsa, Duangvadee Sungkhobol, Sudarshan Kumari, et al.
1
Mapako, Tonderai, Simbarashe Rusakaniko, Maarten J. Postma, Marinus van Hulst, Janet Dzangare, Stellah Ngwende, John Mandisarisa, Ponesai Nyika, David A. Mvere, Owen Mugurungi, and Mufuta Tshimanga
1
Marie Theres Benner and K. Peter Schmitz
1
Mary Nambao, Wezi Kaonga, Yusuf Ahmed, et al.
1
Massachusetts Advocates for Children
1
Maxwell, J.
1
MBC Public Health
1
McGuire, George
1
MCNV, Global Initiative on Psychiatry, and World Granny
1
MEASURE
1
MEASURE Evaluation
1
Medecins Sans Frontieres
1
Meershoek A, Zwerling A, Daftary A, Citro B, Smyth C, Lewis D
1
Melissa Leach
1
Médecins Sans Frontière
1
Millennium Development Goal Acceleration Initiative
1
Minister of Health & Social Welfare (MoHSW), Kingdom of Lesotho
1
Ministry of Agricultur al Development (MOAD)
1
Ministry of Health & Sanitation, Sierra Leone
1
Ministry of Health (MoH), Malawi and ICF International
1
Ministry of Health [Kenya], National AIDS and STI Control Programme (NASCOP)
1
Ministry of Health and Child Care, Zimbabwe
1
Ministry of Health and Child Welfare, Zimbabwe
1
Ministry of Health and Child Welfare,Zimbabwe
1
Ministry of Health and Family Welfare, Directorate-General of Health Services, Mycobacterial Disease Control, National Tuberculosis Control Programme
1
Ministry of Health and Ministry of Industry, Federal Democratic Republic of Ethiopia
1
Ministry of Health and Population, Ministry of Health, Nepal
1
Ministry of Health and Sanitation, Sierra Leone
1
Ministry of Health and Social Services (MOHSS) & Ministry of Education, Arts and Culture (MOEAC)
1
Ministry of Health and Social Services, Windhoek, Namibia
1
Ministry of Health and Social Welfare (MOHSS)
1
Ministry of Health and Social Welfare (MoHSS), Kingdom of Lesotho
1
Ministry of Health and Social Welfare (MoHSW), Kingdom of Lesotho
1
Ministry of Health and Social Welfare, Dar es Salaam, Ministry of Health, Zanzibar, National Bureau of Statistics, Zanzibar, Tanzania, and ICF International
1
Ministry of Health and Social Welfare, Republic of Liberia
1
Ministry of Health and Social Welfare, World Health Organization (WHO) Lesotho Country Office
1
Ministry of Health and Social Welfare, Zimbabwe
1
Ministry of Health Kenya
1
Ministry of Health Malawi
1
Ministry of Health Uganda, NADIC, et al.
1
Ministry of Health, Division of Emergency and Disaster Risk Managemen
1
Ministry of Health, Ethiopia
1
Ministry of Health, Gabarone, Botswana
1
Ministry of Health, Government of Kenya
1
Ministry of Health, Government of Liberia
1
Ministry of Health, Kenya
1
Ministry of Health, Kingdom of Lesotho
1
Ministry of Health, Liberia
1
Ministry of Health, Nepal
1
Ministry of Health, Republic of Botswana
1
Ministry of Health, Republic of Rwanda
1
Ministry of Health, South Africa
1
Ministry of Health, Zimbabwe
1
Ministry of Public Health and Sanitation Kenya
1
Ministry of Public Health& Sanitation. Ministry of Medical Services. Kenya
1
Ministry of Rural Development
1
Misereor
1
Mmbaga, Elia John
1
Mobilising Access to Maternal Health Services in Zambia Programme, District Health Management Teams
1
Mohan P. Joshi Malaïka Ludman Dan Kibuule, et al.
1
Monde, N.
1
Morbidity and Mortality Weekly Report
1
MSF
1
MSH, USAID
1
Mursaleena Islam
1
N. Gebreselassie , C. Lienhardt, L. Anderson et al.
The 7th edition of the Orange Guide provides practical guidance to health workers on the front line of TB control. It includes sections on HIV, MDR-TB and a review of the recommended treatment regimens
Improving the management of childhood tuberculosis within national tuberculosis programmes: research priorities based on a literature review
WHO/HTM/TB/2007.381, 07.02
2nd edition.
Like the original, this second edition of the guidance aims to inform the revision of existing national guidelines and standards for managing Tuberculosis (TB), many of which include guidance on children. It includes recommendations, based on the best available evidence, for improving ...the management of children with TB and of children living in families with TB. National and regional TB control programmes may wish to adapt these recommendations according to local circumstancesmore
The aim of the people-centred framework is to help countries to develop fully prioritized and budgeted NSPs based on a culture of making full use of the available data, which are aligned with national planning cycles and which provide the basis for a robust national response that can accelerate prog...ress towards the goal of ending TB. In addition, applying the framework for other possible applications according to the country’s planning and policy cycle encourages the culture of data utilization and evidence translation into decision making and planning. more
This report presents an overview of the transition process in Azerbaijan, some sustainability aspects and challenges stemming from donor withdrawal from TB-related activities, along with recommendations on how to overcome transition-related difficulties and ensure sustainability.
This is an update of a seven-year TB and Leprosy national strategic plan (TBL-NSP), which extends from 2013 to 2020. The update focuses on the plan covering from 2017-20 and is based on the 2017 external mid-term programme review key findings and recommendations; the global and national End TB strat...e-gies and targets; stakeholders consultation and recent revision of the national TB guidelines.more
The consolidated guidelines are expected to provide the basis and rationale for the development of national guidelines for LTBI management, adapted to the national and local epidemiology of TB, the availability of resources, the health infrastructure and other national and local determinants. The gu...idelines are to be used primarily in national TB and HIV control programmes, or their equivalents in ministries of health, and for other policy-makers working on TB and HIV and infectious diseases. They are also appropriate for officials in other line ministries with work in the areas of health.more
M. SlutskerACTION global health advocacy partnership; ACTION partner oranizations
(2016)
C2
From policy to practice: how the TB-HIV response is working
“The HIV community must place much more focus on TB co-infection than
it has done to date. TB takes the lives of over 1000 people living with HIV
every day, a number which is absolutely unacceptable. This report highlights that
TB d...oesn’t have to be a death sentence for people living with HIV, but we need
more action. By joining forces, the HIV and TB community can finally give this
deadly issue the attention it deserves.”
– Mike Podmore, Director STOPAIDSmore
The SPPCHS project worked with the Ministry of Home Affairs to design a peer education program for prisons to provide knowledge, skills, and tools to prevent and respond to tuberculosis (TB) and HIV in prisons. AIDSFree held two training of trainers (TOT) in Dodoma to train 55 prison officers from 2...6 prison facilities to train prison staff and inmates on the new peer education program. more
The WHO operational handbook on tuberculosis: tuberculosis preventive treatment is the companion, implementation guide to the 2020 WHO guidelines on TB preventive treatment.[1] Just as these guidelines are the first to be released under the rubric of the WHO consolidated TB guidelines, this handbook... will be the first in a modular series of practical guides meant for the implementers of various aspects of the programmatic management TB.more
Because of the limited access to more powerful diagnostic tools, there is a paucity of data regarding the burden of fungal infections in Burkina Faso. The aim of this study was to estimate the incidence and prevalence of serious fungal infections in this sub-Saharan country. We primarily used the na...tional demographic data and performed a PubMed search to retrieve all published papers on fungal infections from Burkina Faso and its surrounding West African countries. Considering the prevalence of HIV infection (0.8% of the population) and a 3.4% incidence of cryptococcosis in hospitals, it is estimated that 459 patients per year develop cryptococcosis. For pneumocystosis, it is suggested that 1013 new cases occur every year. Taking into account the local TB frequency (population prevalence at 0.052%), we estimate the prevalence of chronic pulmonary aspergillosis at 1120 cases. Severe forms of asthma with fungal sensitization and allergic bronchopulmonary aspergillosis are estimated to affect 7429 and 5628 cases, respectively. Vulvovaginal candidiasis may affect 179,000 women, and almost 1,000,000 children may suffer from tinea capitis. Globally, we estimate that roughly 1.4 million people in Burkina Faso (7.51% of the population) suffer from a serious fungal infection. These data should be used to drive future epidemiological studies, diagnostic approaches, and therapeutic strategies.more
The Region of the Americas comprises 46 countries and territories and Brazil and Peru are among the WHO high- TB burden
countries. T o illustrate the recent increase in TB incidence in the region, we selected 12 countries from Latin America (Argentina,
Brazil, Chile, Colombia, Ecuador, El Salvador..., Mexico, Panama, Paraguay, Peru, Uruguay and Venezuela), which account for approximately 80% of the total estimated TB cases in the region.more
The WHO Global Tuberculosis Report 2022 provides a comprehensive and up-to-date assessment of the TB epidemic, and of progress in prevention, diagnosis and treatment of the disease, at global, regional and country levels. This is done in the context of global TB commitments, strategies and targets.
...
The 2022 edition of the report is as usual, based primarily on data gathered by WHO from national ministries of health in annual rounds of data collection. In 2022, 202 countries and territories with more than 99% of the world’s population and TB cases reported datamore
This analysis focused on the chronic form of HAT caused by T. b. gambiense, as it contributes to the majority of disease burden. Information from the literature review,
product development landscape, and stakeholder interviews was compiled to:
- Identify use cases and understand current diagnosti...c practices and tools associated with each use case.
- Analyze progress toward robust diagnostics for HAT across different biomarkers.
- Develop recommendations for steps to improve the availability, access, and adoption of HAT diagnostic tools.more
The Creditor Reporting System was analysed for official development assistance funding disbursements towards TB control in 11 conflict-affectedstates, 17 non-conflict-affected fragile states and 38 comparable non-fragile states. The amounts of funding, funding relative to burden, funding relative to... malaria and human immunodeficiency virus (HIV) control, disbursements relative to commitments, sources of funding as well as funding activities were extracted and analysed.more
Previous advocacy efforts have achieved tangible goals in terms garnering political commitments
to increase financing for TB—as seen at the 2018 UN High-Level Meeting on TB. The challenge
now is to ensure that these commitments are actually met within a global biomedical research
ecosystem that... is designed and incentivized to prioritize the health needs of wealthy populationsmore
Background: Community health worker (CHW) programmes are a valuable component of primary care in resource-poor settings. The evidence supporting their effectiveness generally shows improvements in disease-specific outcomes relative to the absence of a CHW programme. In this study, we evaluated expan...ding an existing HIV and tuberculosis (TB) disease-specific CHW programme into a polyvalent, household-based model that subsequently included non-communicable diseases (NCDs), malnutrition and TB screening, as well as family planning and antenatal care (ANC).
Methods: We conducted a stepped-wedge cluster randomised controlled trial in Neno District, Malawi. Six clusters of approximately 20 000 residents were formed from the catchment areas of 11 healthcare facilities. The intervention roll-out was staggered every 3 months over 18 months, with CHWs receiving a 5-day foundational training for their new tasks and assigned 20–40 households for monthly (or more frequent) visits.
Findings: The intervention resulted in a decrease of approximately 20% in the rate of patients defaulting from chronic NCD care each month (−0.8 percentage points (pp) (95% credible interval: −2.5 to 0.5)) while maintaining the already low default rates for HIV patients (0.0 pp, 95% CI: −0.6 to 0.5). First trimester ANC attendance increased by approximately 30% (6.5pp (−0.3, 15.8)) and paediatric malnutrition case finding declined by 10% (−0.6 per 1000 (95% CI −2.5 to 0.8)). There were no changes in TB programme outcomes, potentially due to data challenges.more
About one fourth of the world’s population is estimated to have been infected with the tuberculosis (TB) bacilli, and about 5–10% of those infected develop TB disease in their lifetime. The risk for TB disease after infection depends on several factors, the most important being the person’s im...munological status. TB preventive treatment (TPT) given to people at highest risk of progressing from TB infection to disease remains a critical element to achieve the global targets of the End TB Strategy, as reiterated by the second UN High Level Meeting on TB in 2023. Delivering TPT effectively and safely necessitates a programmatic approach to implement a comprehensive package of interventions along a cascade of care: identifying individuals at highest risk, screening for TB and ruling out TB disease, testing for TB infection, and choosing the preventive treatment option that is best suited to an individual, managing adverse events, supporting medication adherence and monitoring programmatic performancemore