The response to a cholera outbreak must focus on limiting mortality and reducing the spread of the disease. It should be comprehensive and multisectoral, including epidemiology, case management, water, sanitation and hygiene, logistics, community engagement and risk communication. All efforts must b...e well coordinated to ensure a rapid and effective response across sectors.
This document provides a framework for detecting and monitoring cholera outbreaks and organizing the response. It also includes a short section linking outbreak response to both preparedness and long-term prevention activities.
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Although estimated to cause the ninth largest disease burden among individual infectious diseases, leishmaniasis is largely ignored in discussions of tropical disease priorities [1,2]. This consignment to critical oblivion results from its complex epidemiology and ecology, the lack of simple, easily...-applied tools for case management and the paucity of current incidence data, and often results in a failure on the part of policy-makers to recognize its importance [3,4]. Based on the World Health Assembly Resolu tion 2007/60.13, the World Health Organization (WHO) convened the Expert Committee on Leishmaniasis in March 2010, which subsequently issued the first updated technical report on leishmaniasis in more than 20 years [5,6].
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Chagas disease caused by Trypanosoma cruzi is a public health issue in Latin America. This highly diverse parasite is divided into at least seven discrete typing units (DTUs) TcI-TcVI and Tcbat. Some DTUs have been associated with geographical distribution in epidemiological scenarios and clinical m...anifestations, but these aspects remain poorly understood. Many studies have focused on studying the parasite and its vectors/hosts, using a wide variety of genetic markers and methods. Here, we performed a systematic review of the literature for the last 20 years to present an update of DTUs distribution in the Americas, collecting ecoepidemiological information. We found that the DTUs are widespread across the continent and that there is a whole gamma of genetic markers used for the identification and genotyping of the parasite. The data obtained in this descriptor could improve the molecular epidemiology studies of Chagas disease in endemic regions.
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The objectives of the meeting were:
1. To update the current status of the disease transmission, country capacities and plans for tackling the disease.
2. To understand the epidemiology including disease distribution and risk, the models
for estimating under-detection, the geographical variati...ons of in clinical presentation,
the roles of domestic and wild animal reservoirs and the subsequent different
transmission patterns and control approaches, including vector control.
3. To update current research and development efforts for improving diagnostic and
treatment tools.
4. To define the goals for achieving the control of r-HAT, the need for a multisectoral
approach and to discuss the strategy for controlling r-HAT and the coordination
mechanisms.
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Classical rabies caused by RABV occurs worldwide besides some isolated countries and Western Europe that are regarded rabies free. Carnivores, especially of the canidae family represent the principal reservoir species and are responsible for the maintenance of the infectious cycle and hence for the ...presence of the disease (see Epidemiology of rabies). While wildlife rabies maintained by different reservoirs hosts predominantly occurs in the Northern hemisphere, canine rabies is by far more important for public health in the developing world.
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Education and information about Chagas Disease, Triatomine bugs, Kissing Bugs, fact sheets, information for special groups, prevention and control, epidemiology, diagnosis and treatment for Health Professionals.
Website last accessed on 18.03.2023
Education and information about ascariasis, including fact sheets and information on prevention and control, epidemiology, diagnosis and treatment.
Visceral leishmaniasis is an important disease in East Africa where recurrent outbreaks occur. Leishmania-HIV coinfected people have high chance of developing the full-blown clinical disease, and high relapse and mortality rates. Poverty, malnutrition and population movements in endemic areas increa...se the risk of developing VL. Early diagnosis and effective prompt treatment reduce the prevalence of the disease and prevents disabilities and death. This course aims at providing health workers with the necessary knowledge to understand the epidemiology, diagnosis, treatment, surveillance and outbreak investigation of this important disease in East Africa.
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Website last accessed on 18.03.2023
Education and information about hookworm including fact sheets and information on prevention and control, epidemiology, diagnosis and treatment.
Course information
Yaws is targeted for eradication by WHO in the 2021-2030 NTD Roadmap. It is therefore crucial to know how to identify cases, design and implement activities to eradicate the disease at the community level.
In the context of integration of skin NTDs it is vital to learn to recogn...ize a disease targeted for eradication. At the individual level yaws lesions may mimic other skin diseases. At the community level, it is key to know how to design and implement the total community treatment strategy and monitor its impact. This course aims at providing health workers with the basic knowledge to understand the epidemiology, diagnosis, treatment, impact, eradication strategy and reporting of yaws.
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Course information
Yaws is targeted for eradication by WHO in the 2021-2030 NTD Roadmap. It is therefore crucial to know how to identify cases, design and implement activities to eradicate the disease at the community level.
In the context of integration of skin NTDs it is vital to learn to recogn...ize a disease targeted for eradication. At the individual level yaws lesions may mimic other skin diseases. At the community level, it is key to know how to design and implement the total community treatment strategy and monitor its impact. This course aims at providing health workers with the basic knowledge to understand the epidemiology, diagnosis, treatment, impact, eradication strategy and reporting of yaws.
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Schistosomiasis is a prevalent parasitic, neglected tropical disease (NTD) affecting over 220 million people globally, especially in sub-Saharan Africa (SSA). The pathology of this disease in terms of intestinal, liver and urinary presentations is well-known, yet its chronic effect on host genitalia... is often ignored or overlooked. Male genital schistosomiasis (MGS) is a gender-specific manifestation of urogenital schistosomiasis (UGS), associated with the presence of Schistosoma haematobium eggs and related pathologies in genitalia of men inhabiting or visiting endemic areas in SSA. Despite the first reported by Madden, the epidemiology, diagnostic testing and case management of MGS are not well-described owing to limited research and diminishing focus over several decades.
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Pathogens . 2021 Nov 16;10(11):1493.doi: 10.3390/pathogens10111493
.Chronic manifestations of Chagas disease present as disabling and life-threatening condi-tions affecting mainly the cardiovascular and gastrointestinal systems. Although meaningful research has outlined the different molecular mech...anisms underlying Trypanosoma cruzi’s infection and the host-parasite interactions that follow, prompt diagnosis and treatment remain a challenge, particu-larly in developing countries and also in those where the disease is considered non-endemic. This review intends to present an up-to-date review of the parasite’s life cycle, genetic diversity, virulence factors, and infective mechanisms, as well as the epidemiology, clinical presentation, diagnosis, and treatment options of the main chronic complications of Chagas disease.
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Front. Public Health, 02 July 2019 Sec. Infectious Diseases: Epidemiology and Prevention
Volume 7 - 2019 | https://doi.org/10.3389/fpubh.2019.00166
Chagas disease (CD) is an anthropozoonosis caused by the protozoan parasite Trypanosoma cruzi, that affects about 6–8 million people worldwide (1) a...nd causes approximately 50,000 deaths per year. Another 65–100 million people are living in areas at risk for infection worldwide (2–4). Even though over a century has passed since its discovery, CD remains one of the leading public health problems for most Latin American countries
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As part of the UN’s data strategy—which seeks to nurture data as a strategic asset for insight, impact and integrity—UNAIDS plays an indispensable role in generating data for effective action against the AIDS pandemic. It leads the
world’s most extensive data collection on HIV epidemiology,... programme coverage, policy and finance, and it publishes the most authoritative and up-to-date information on the HIV pandemic and response. The UNAIDS database of countryreported data is a foundational pillar for global and regional AIDS programmes, research, advocacy and resource mobilization
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Slideset updated regularly to reflect the state of the COVID-19 pandemic and to include the latest data and guidance on best practices for diagnosis and management; topics include global epidemiology, screening and diagnosis, natural history and clinical presentation, disease severity, medical manag...ement, and treatment options.
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n light of the potential risk posed by SARS-CoV-2 variants, in January 2021 WHO organized an ad hoc consultation to discuss the development of an R&D agenda in response to existing and emerging SARS-CoV-2 variants.
The key objectives were to identify the critical research questions related to var...iants and agree on a research approach to address them. Six breakout groups covered a range of specific issues related to COVID-19 variants: Epidemiology and mathematical modelling; evolutionary biology; animal models; assays and diagnostics; clinical management and therapeutics; and vaccines.
This report is a summary of presentations and panel discussions.
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Expert international faculty present weekly, concise MedicalMinute updates, host biweekly Question and Answer Webinars, and author a continually updated downloadable slideset including the latest data on COVID-19 epidemiology and clinical management; specific topics include best practices and ongoin...g research in screening, prevention, diagnosis, disease management, and treatment for diverse patient populations.
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In response to COVID-19, countries around the world have implemented several public health and social measures (PHSM), such as movement restrictions, closure of schools and businesses, and international travel restrictions.1 As the local epidemiology of the disease changes, countries will adjust (i....e. loosen or reinstate) these measures according to the intensity of transmission.
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According to WHO, infection prevention and control (IPC) is a scientific approach and practical solution designed to prevent harm caused by infection to patients and health workers. It is grounded in infectious diseases, epidemiology, social science and health system strengthening. IPC occupies a un...ique position in the field of patient safety and quality universal health coverage since it is relevant to health workers and patients at every single health-care encounter. Poor WASH and IPC lead to health acquired infections, transmission of diseases from health facilities to communities and increased use of antibiotics and exacerbate outbreak and spread of infections- in this case- COVID- 19. On the contrary, effective IPC reduces hospital-acquired infections by at least 30% (WHO 2016).
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