Buruli ulcer caused by Mycobacterium ulcerans is a neglected tropical disease characterized by extensive ulceration involving predominantly the upper and lower limbs of patients. The disease is common in rural tropical communities in West and Central Africa, where access to proper health care is lim...ited. Pathogenesis of the characteristic painless ulcers is linked to the elaboration by M. ulcerans of a lipid toxin called mycolactone that has potent cytopathic, immunosuppressive, and analgesic effects on a host of cells in cutaneous tissues. Mycolactone is known to profoundly inhibit secretion of a plethora of proteins that are essential for wound healing. Even though a combination antibacterial therapy of streptomycin and rifampicin for 8 weeks is effective for treatment, it relies on good and appropriate wound management to prevent secondary bacterial infections and improve healing. Evidence-based interventions for wound care in Buruli ulcer disease are often lacking and have relied on expert advice and recommendations. Surgical interventions are limited to debridement of necrotic tissue and grafting of extensive ulcers, usually after antibiotic therapy. Patients’ rehabilitation is an important component of care to reduce disabilities associated with the disease and proper integration into the community after treatment.
more
This global progress report attempts to lay the groundwork for the kind of accelerated action needed. Section 1 presents key data, trends and developments in women’s, children’s and adolescents’ health and well-being. That is followed in Section 2 by a deeper dive into the impact of the COVID-...19 pandemic, which has created and contributed to many threats and challenges to progress for women, children and adolescents. In Section 3, the report concludes with recommendations for accelerating progress towards the achievement of the 2030 Agenda even in such challenging times, with an emphasis on partnership
and clear-eyed recognition of the consequences of failing to do better.
more
The COVID-19 pandemic is having a profound negative effect on the global economy and is occurring in the context of a rapidly changing climate. This year is expected to be the second hottest in recorded history. Weather forecasts for 2020 indicate a high probability that extreme weather will adverse...ly affect food production in many countries. This brief draws on historical evidence and demonstrates that reductions in national food availability caused by severe weather events tend to be considerably larger in magnitude when they occur during global economic downturns. The risks posed by this dual threat are particularly high for poorer countries that are net food importers. Taking actions to mitigate these adverse effects in the short-term, while building the resilience of agri-food systems to future shocks is critical for avoiding major contractions in food availability and associated risks of food insecurity.
more
Ten Principles of Catholic Social Teaching
accessed July 2020
The WASH in Ebola DROPBOX (click to access on hte website https://www.dropbox.com/sh/po2i7g09grfb94d/AADRA_CE5HNSEP1vBxgWOnJ3a?n=124754289) supports operational agencies responding to Ebola providing all available technical guidelines, manuals, coordination and training related information. The DROP...BOX continues to be updated on regular basis, if you have any relevant documents to share, please send them to washinebola@gmail.com.
more
Mortality and global health estimates.
Accessed August 6, 2019
Global and Regional View of Vaccine Acceptance and Related Behaviors.
This new interactive tool captures information on knowledge, attitudes and behaviors around vaccines, masking, testing and more from 12 million people in 115 countries.
Insights and analyses on how to use the data were written ...by researchers and social and behavior change communication experts at CCP in collaboration with WHO’s Global Outbreak Alert and Response Network. This site is intended to be used by policy makers, health officials and practitioners at national and subnational levels to better understand the behavioral drivers behind vaccine uptake, masking and physical distancing among other behaviors that affect the spread of COVID-19.
more
Handout presentations in PDF for illustrating lectures
Accessed May 2014
World Bank Open Data: Free and open access to global development data Also available in Spanish, French, Arabic and Chinese
Accessed 26 February 2019.
Specific Issues and a Model of Care
Accessed; 08.10.2019
Universal health coverage ensures everyone has access to the health services they need without suffering financial hardship as a result. In December 2012, a UN resolution was passed encouraging governments to move towards providing universal access to affordable and quality health care services. As ...countries move towards it, common challenges are emerging -- challenges to which research can help provide answers.
more
In the event of an accident or medical emergency, First Aid saves lives. Keeping the patient alive and safe until the arrival of expert professional help is a vital part of the chain of care which leads to recovery. The principle of First Aid must be simple skills, clearly taught and capable of bein...g performed in a stressful situation by those with no medical training. This manual is intended to offer a basic level of First Aid for members of the general public.
The contents of this manual are offered as a first edition of European First Aid Guidelines for general use. As such they are compatible with current practise, with other specialist guidelines (for example regarding the management of burns) and with the evidence base where one exists. These guidelines will be updated on a regular basis by the JOIN Clinical Working Group.
more
WHO Package of Essential NCD Interventions (PEN)
Accessed March 18,2019
Handout presentations in PDF for illustrating lectures
Accessed May 2014
short information for migrants on how to access medicines in Germany
Many migrants find themselves with limited access, if any, to information about risks, prevention measures, health care and other essential services. Migrants in transit, those in need of international protection or without legal status are likely to be particularly vulnerable, as well as those who ...are homeless, held in detention, living in camps, formal or informal settlements or otherwise precarious conditions
more
Rediscovering Biology
Molecular to Global Perspectives
Accessed: 03.09.2019
Millennium Development Goal 8E aims for affordable access to essential medicines. Essential medicines, as defined by WHO, are those that “satisfy the health-care needs of the majority of the population” and that should therefore “be available at all times in adequate amounts”. However, there... is a category of medicines that faces a unique challenge in terms of availability. These are the medicines governed by the international conventions on narcotic and psychotropic substances. “Controlled medicines” is the common definition for pharmaceuticals whose active principles are listed under the 1961 United Nations Single Convention on Narcotic Drugs as amended by the 1972 Protocol, such as morphine and methadone; the 1971 United Nations Convention on Psychotropic Substances, such as diazepam and buprenorphine; and the 1988 United Nations Convention against Illicit Traffic in Narcotic Drugs and Psychotropic Substances, such as ergometrine and ephedrine. The conventions list substances in “Schedules” according to their different levels of potential for abuse and harm, and the commensurate severity of control measures to be applied by countries.
more
Time for recognition of lay counsellors
Accessed November 2017
WHO is working with Viamo, a global social enterprise improving lives via mobile, to provide WHO’s COVID-19 information, including vaccines, to the hardest to reach populations, in their languages, through the mobile phones they own. This includes people with simple phones (feature phones) or with... limited access to the internet. Since the onset of COVID-19, Viamo’s 3-2-1 Service has become a trusted, toll-free source of life-saving COVID-19 health information for people in 19 countries. Listeners dial in and access important messages that help them make better informed decisions to live healthier lives.
more