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Planning for public health emergencies should ensure that capabilities developed during previous emergencies are maintained, incorporated, and put into practice when a new event of public health concern arises. Investments in pandemic preparedness lead to more rapid detection and a stronger
...
response to public health threats, thereby shielding communities from the debilitating social and economic effects of epidemics and pandemics. The Pan American Health Organization (PAHO) recognizes the efforts of countries in the Region of the Americas to develop and/or strengthen their respiratory pathogen pandemic plans. PAHO supports planning activities with tools and expertise, aligning these efforts with the Preparedness and Resilience for Emerging Threats (PRET) initiative. The PRET initiative is an innovative approach to improving disease pandemic preparedness. It recognizes that the same systems, capacities, knowledge, and tools can be leveraged and applied for groups of pathogens based on their mode of transmission (respiratory, vector-borne, foodborne etc.). The PRET initiative incorporates the latest tools and approaches for shared learning and collective action established during the COVID-19 pandemic and other recent public health emergencies.
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Severe and difficult asthma in a low- and middle-income country (LMIC) can relate to lack of availability of basic medications; potentially reversible factors such as poor adherence or comorbidities such as obesity inhibiting a good response to trea
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tment; and (rarely) true severe, therapy-resistant asthma. However, definitions of severity should encompass not merely doses of prescribed medication, but also underlying risk. The nature of asthmatic airway disease shows geographical variation, and LMIC asthma should not be assumed to be phenotypically the same as that in high-income countries (HICs). The first assessment step is to ensure another diagnosis is not being missed. Largely, political action is needed if children with asthma are to get access to basic medications. If a child is apparently not responding to low dose, simple medications, the next step is not to increase the dose but perform a detailed assessment of what factors (for example co-morbidities such as obesity, or social factors like poor adherence) are inhibiting a treatment response; in most cases, an underlying reason can be found. An assessment of risk of future severe asthma attacks, side-effects of medication and impaired lung development is also important. True severe, therapy-resistant asthma is rare and there are multiple underlying molecular pathologies. In HICs, steroid-resistant eosinophilia would be treated with omalizumab or mepolizumab, but the cost of these is prohibitive in LMICs, the biomarkers of successful therapy are likely only relevant to HICs. In LMICs, a raised blood eosinophil count may be due to parasites, so treating asthma based on the blood eosinophil count may not be appropriate in these settings.
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Asthma has a significant impact on people of all ages, particularly children. A lack of universally accepted case definition and confirmatory tests and a poor understanding of major risks interfere with a global response. We aimed to provide global
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estimates of asthma prevalence and cases in 2019 across four main epidemiological case definitions – current wheezing, ever wheezing, current asthma, and ever asthma. We further investigated major associated factors to determine regional and national distributions of prevalence and cases for current wheezing and ever asthma.
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The active participation and engagement of health and care workers (HCWs) in health emergency preparedness, readiness and response is crucial to support risk communication, community engagement and infodemic management (RCCE-IM) interven
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tions during emergencies. HCWs hold unique positions in society – repeatedly being identified among the main influencers of people’s behaviours: they are one of the most trusted sources of health information and advice in communities and role models for the acceptance and uptake of protective measures during health emergencies. On the frontline, HCWs have valuable insights and knowledge that can be harnessed to support health emergencies across the entire emergency cycle. Between October and December 2023, the WHO Regional Office for Europe interviewed key informants on strategies and experiences to meaningfully engage HCWs during emergencies
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Médecins Sans Frontières (MSF) has set up a 20-bed cholera treatment unit (CTU) at the Renk Civil Hospital in South Sudan, in response to a cholera outbreak declared by the Ministry of Health (MoH) on 28 October. We call on all organisations in Up
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per Nile state to help prevent the spread of the disease within Upper Nile State and beyond.
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This video provides an overview of how a virus spreads, invades the body’s cells, and results in symptoms, as well as how a vaccine works to use the body’s natural immune response to protect us from these germs.
Specific attention is paid to th
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e unique aspects of the COVID-19 virus, the mRNA vaccine, the vaccine variations and boosters that are a source of confusion.
This video is part of our Supporting Vaccination Toolkit for Community Health Workers (CHWs). This free digital toolkit is designed to increase the self-efficacy and effectiveness of CHWs in conducting vaccine outreach in communities, ultimately increasing vaccination rates.
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The indicators and questions in this document are designed for use by national AIDS programmes and partners to assess the state of a country’s HIV and AIDS response, and to measure progress towards achieving national HIV targets. Countries are enc
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ouraged to integrate these indicators and questions into their ongoing monitoring efforts and to report comprehensive national data through the Global AIDS Monitoring (GAM) process. In this way they will contribute to improving understanding of the global response to the HIV epidemic, including progress that has been made towards achieving the commitments and global targets set out in the new United Nations Political Declaration on HIV and AIDS: Ending Inequalities and Getting on Track to End AIDS by 2030, adopted in June 2021, and the linked Sustainable Development Goals.
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Zambia has completed the implementation of the National TB Strategic Plan (2017-2021) that set in motion the TB elimination agenda in Zambia through coordinated and accelerated TB response. During this period, the National TB and Leprosy Programme (
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NTLP) registered tremendous success.
The NTLP is poised to attain the ambitious goal pronounced by the government of eliminating TB by 2030, in line with the Sustainable Development Goals (SDGs) and the World Health Organization End TB Strategy. The programme exponentially increased TB notifications from as low as 35,922 people with TB in 2018 to 40,726 in 2020 and in 2021 the TB notifications rose to 50,825 (a 25% increase against 2020 performance). The NTLP also registered incredible success in sustaining high TB Preventive Treatment (TPT) initiations among persons living with HIV and a high TB treatment success rate among drug-susceptible TB cases. New and relapse TB notifications in children below 15 years increased by 43%, from 2,724 in 2020 to 3,890 in 2021. TB notifications ratio between children aged 0-4 and 5-14 was 0.9, an improvement from what we achieved in 2018 (the ratio was 0.7). The proportion of TB patients who are HIV positive continued to decrease, reaching 34% in 2021 from 39% in 2020. Sustained increases in TB notifications, treatment success rate, and TPT initiations have resulted in a rapid decrease in the TB incidence rate that reached 307 per 100,000 population in 2021 against a rate of 391 in 2015.
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Guidelines for the treatment of human African trypanosomiasis. Web Annex A. Commissioned by WHO Cochrane Response
In contrast to bilateral aid, aid disbursed from
multilateral institutions increased significantly at the onset
of the COVID-19 pandemic. Yet, at a time when a coherent
and effective multilateral response is needed most, the
COVID-19 pandemic re
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vealed a shifting landscape of donor
agencies that struggle with basic functions, such as crossnational coordination. While multilaterals are uniquely
positioned to transcend national priorities and respond
to pandemics, functionally we find official development
assistance (ODA) from these entities may increasingly
mimic the attributes of bilateral aid. We explore three
important, but not comprehensive, attributes of aid leading
up to and during the COVID-19 pandemic: (1) earmarking,
(2) donor concentration and (3) aid modality.
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Efficacious antimalarial medicines are critical to malaria control and elimination. Continuous monitoring of their efficacy is needed to inform treatment policies in malaria-endemic countries, and to ensure early detection of, and response to, drug
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resistance.
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Public health challenges over the past decade have highlighted the importance of approaching health through a holistic lens of human, animal, and environmental sectors, recognizing the need for a collaborative response against shared threats. Zoonot
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ic diseases, transmitted between humans and animals through their shared environment, are at the forefront of the threats requiring collaborations that span human health, natural ecosystems, and food systems.
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The PRET simulation exercise packages are a comprehensive set of resources designed to support countries and different stakeholders in conducting tailored exercises for respiratory pathogen preparedness and response planning. These packages are vers
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atile and adaptable, making them suitable for use by countries, as well as public and private institutions in diverse settings.
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As the United Nations’ public health agency, WHO has an important role to play in the global public health response to events involving the possible deliberate use of biological and chemical hazards against a human population.
This channel offers videos designed to strengthen the logistics and supply chain preparedness of the National Public Health Institutes (NPHIs) in the WHO Eastern Mediterranean Region (EMR) for effective response during health emergencies such as pan
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demics, epidemics, and other health crises. Tailored for NPHI professionals involved in procurement, laboratory management, and emergency planning, the course provides a comprehensive, modular framework focused on building resilient systems and capabilities.
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Parliaments and parliamentarians play a unique and powerful role in achieving health security preparedness through their various responsibilities: law-making, oversight, budgetary allocation, and citizen representation. High-level reviews of the response
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to the COVID-19 pandemic emphasized the importance of state capacity, social trust, and leadership when it comes to health emergency preparedness. Parliaments and parliamentarians are extremely well positioned to support, build, and strengthen these three aspects.
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There is widespread recognition of the growing threat of infectious disease epidemics and pandemics spreading across countries or continents—especially following the recent Ebola and COVID-19 pandemics. Vulnerable groups (including children, older adults, ethnic minorities and other at-risk group
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s) have disproportionately borne the brunt of significant health, social, and economic effects of these epidemics and pandemics, with varying degrees of support received depending on the context. While many argue that communities should or need to play a critical role in supporting and leading preparedness and response efforts, work still needs to be done to engage them effectively. In many instances, modes of engagement with communities—especially by state authorities–have come too late, often as an afterthought are not adequately thought through and have undermined public trust in and support for, disease prevention and control measures
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Developed through broad and inclusive consultation, and aligned with the WHO Global Health Sector Strategies and the Sustainable Development Goals, the framework promotes a people-centred approach and antimicrobial stewardship across 5 key domains: prevention and
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response, surveillance, research and innovation, laboratory capacity, and governance.
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The WHO Health Security Learning Platform (HSLP) is an online training hub that provides courses and toolkits to strengthen countries’ capacities in public-health preparedness, emergency response, and implementation of the International Health Reg
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ulations (IHR). It offers self-paced modules and practical training materials on topics such as outbreak response, points-of-entry management, One Health, and laboratory preparedness, helping health professionals build essential skills for global health security.
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The page lists and describes a number of mobile apps and digital tools provided by WHO/EMRO to support prevention, monitoring and response to epidemic- and pandemic-prone diseases. These include apps focused on diseases such as Middle East Respirat
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ory Syndrome (MERS), Zika virus disease, travel-related infection prevention, and general infection-control guidance.
In addition, there are tools such as assessment instruments for infection prevention and control programmes (IPC), and portals for emerging infectious-disease information and outbreak investigation support.
Overall, the page serves as a gateway to digital resources that help healthcare workers and public-health professionals access WHO technical guidance, coordinate outbreak responses, and implement control measures for a variety of infectious-disease threats.
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