Cryptococcal disease is one of the most common opportunistic infections among people living with advanced HIV disease and is a major contributor to severe illness, morbidity, and mortality, particularly in sub-Saharan Africa.
These guidelines update the recommendations that were first released i...n 2018 on diagnosing, preventing, and managing cryptococcal disease. In response to important new evidence that became available in 2021, these new guidelines strongly recommend a single high dose of liposomal amphotericin B as part of the preferred induction regimen for the treatment of cryptococcal meningitis in people living with HIV. This simplified regimen - a single high dose of liposomal amphotericin B paired with other standard medicines (flucytosine and fluconazole) - is as effective as the previous WHO standard of care, with the benefits of lower toxicity and fewer monitoring demands.
The objective of these guidelines is to provide updated, evidence-informed recommendations for treating adults, adolescents and children living with HIV who have cryptococcal disease. These guidelines are aimed at HIV programme managers, policymakers, national treatment advisory boards, implementing partners and health-care professionals providing care for people living with HIV in resource-limited settings with a high burden of cryptococcal disease.
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Children's Health and the Environment WHO Training Package for the Health Sector World Health Organization
For each medicine the Formulary provides information on use, dosage, adverse effects, contraindications and warnings, supplemented by guidance on selecting the right medicine for a range of conditions
This new edition and fully updated publication replaces the 2012 UCG and is being circulated free of charge to all public and private sector prescribers, pharmacists, and regulatory authorities in the country
This new publication presents the continuing and emerging challenges to children’s environmental health.
The survey highlights changes that have taken place in Bangladesh’s demographic and health situation since the previous BDHS surveys. The survey provides important information for policymakers and program personnel in addressing the monitoring and evaluation needs of the 4th Health, Population and... Nutrition Sector Program (4th HPNSP) of the Ministry of Health Family Welfare (MOHFW).
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As slight hints of recovery begin to surface in West Africa, UNICEF is looking at the impact of Ebola on children and the response and work of the affected communities in the report, Ebola: Getting to zero – for communities, for children for the future. The document traces some of the outbreak’s... history along with the stories of survivors, health care workers and those working to make things better on the ground. The report also helps map out the actions that urgently must continue to help build resiliency and resuscitate basic services and systems decimated by Ebola.
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Therapeutics Information and Pharmacovigilance Centre | TIPC
Malawi is a small and beautiful country in south-central Africa. It is divided into three administrative regions: south, central and north. The regions are further subdivided into 28 districts. The Southern Region is the most densely populated, while the Northern Region is the least populated.