Despite a historical association with poor tolerability, a comprehensive review on safety of antileishmanial chemotherapies is lacking. We carried out an update of a previous systematic review of all published clinical trials in visceral leishmaniasis (VL) from 1980 to 2019 to document any reported ...serious adverse events (SAEs).
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High prevalence of target diseases in rural and developing nations, increased prevalence of malnutrition across the globe, lack of hygiene and poor sanitation facilities, Migratory patterns of population, introduction of new chemical entity in the field of therapeutics, favorable government regulati...ons, and increased R&D investments are key factors contributing to high CAGR of point of care diagnostics market during the forecast period.
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The effective vaccine management (EVM) workshop, jointly organized by WHO and UNICEF, was attended by participants from 13 countries, who reviewed the various EVM benchmarks, identified the gaps in policies, guidelines, SOPs and job aids, and developed respective country action plans to fill these g...aps. This meeting report outlines the proceedings and outcomes of the workshop conducted in Bangkok, Thailand, in December 2024
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Small drinking-water supplies commonly experience operational, managerial, technical and resourcing challenges that impact their ability to deliver safe and reliable services. The needs and opportunities associated with these supplies therefore warrant explicit consideration in policies and regulati...ons.
These Guidelines, specifically tailored to small water supplies, build on over 60 years of guidance by the World Health Organization (WHO) on drinking-water quality and safety. They focus on establishing drinking-water quality regulations and standards that are health based and context appropriate; on proactively managing risks through water safety planning and sanitary inspections; and on carrying out independent surveillance. The guidance is intended primarily for decision-makers at national and subnational levels with responsibility for developing regulatory frameworks and support programmes related to these activities. Other stakeholders involved in water service provision will also benefit from the guidance in this document.
Designed to be practical and accessible, these Guidelines offer clear guidance that is rooted in the principle of progressive improvement. State-of-the-art recommendations and implementation guidance are provided, drawn from a comprehensive evidence review and established good practices. Additionally, case examples are provided from countries and areas around the world to demonstrate how the guidance in this publication has been implemented in practice in a wide variety of contexts.
Together with WHO’s 2024 Sanitary inspection packages – a supporting tool for the Guidelines for drinking-water quality: small water supplies, these Guidelines update and supersede WHO’s 1997 Guidelines for drinking-water quality. Volume 3: surveillance and control of community supplies. Key changes to this updated publication include a greater focus on preventive risk management and a broader range of small water supplies covered, including those managed by households, communities and professional entities.
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Las Guías para la calidad del agua de consumo humano: pequeños sistemas de abastecimiento de agua se han elaborado para tratar las necesidades y oportunidades asociadas a los pequeños sistemas de abastecimiento, con el fin de facilitar la mejora progresiva hacia unos servicios seguros y sostenibl...es de agua de consumo humano para todas las personas. Estas Guías se basan en la recomendación principal de las Guías para la calidad del agua de consumo humano de la Organización Mundial de la Salud, y proporcionan orientación sobre la aplicación de esas recomendaciones a los pequeños sistemas de abastecimiento de agua en particular. El objetivo de estas Guías consiste en ayudar a los gobiernos y a los profesionales a mejorar la seguridad del agua de consumo humano suministrada a través de pequeños sistemas de abastecimiento.
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Настоящее «Руководство по обеспечению качества питьевой воды: маломасштабные системы водоснабжения» было разработано для удовлетворения потребностей и использ...вания возможностей, связанных с маломасштабными системами водоснабжения, в целях содействия постоянному совершенствованию системы устойчивого снабжения всего населения безопасной питьевой водой. Настоящее Руководство основано на главной рекомендации Руководства по обеспечению качества питьевой воды Всемирной организации здравоохранения и содержит руководящие указания в отношении выполнения этой рекомендации, в частности применительно к маломасштабным системам водоснабжения. Настоящее Руководство призвано помочь правительствам и отрасли повысить безопасность питьевой воды, доставляемой маломасштабными системами водоснабжения.
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The Guidelines for drinking-water quality: small water supplies have been developed to address the needs and opportunities associated with small supplies to facilitate progressive improvement towards safe and sustainable drinking-water services for all. These Guidelines are based on the principal re...commendation in the World Health Organization’s Guidelines for drinking-water quality, and they provide guidance on applying that recommendation to small water supplies in particular. These Guidelines aim to help governments and practitioners improve the safety of drinking-water delivered through small supplies.
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وقد وُضعت هذه الإرشادات المعنونة "إرشادات بشأن مياه الشرب: إمدادات المياه الصغيرة" لتناول الاحتياجات والفرص المرتبطة
بإمدادات المياه الصغيرة وتيسير التحسين التد...ريجي نحو خدمات مياه شرب آمنة ومستدامة للجميع.
تستند هذه الإرشادات إلى التوصية الرئيسية الواردة في إرشادات منظمة الصحة العالمية بشأن جودة مياه الشرب وتوفّر إرشادات حول تطبيق هذه التوصية على إمدادات المياه صغيرة الحجم على وجه الخصوص.
تهدف هذه الإرشادات إلى مساعدة الحكومات والممارسين على تحسين سلامة مياه الشرب المقدمة من خلال الإمدادات الصغيرة.
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Each year, dozens of communities around the world face natural disasters, disease outbreaks, and other emergencies. Scientists think that a worldwide influenza outbreak will happen sometime in the next decade. The purpose of this guide is to help local leaders and community organizers bring together... the community to help plan for disease outbreaks and other emergencies. This guide uses the lessons from communities that have already dealt with disease outbreaks and also uses other often-used tools to create discussion among community members and effectively garner their insight
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