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Buruli ulcer caused by Mycobacterium ulcerans is a neglected tropical disease characterized by extensive ulceration involving predominantly the upper and lower limbs of patients. The disease is common in rural tropical communities in West
...
and Central Africa, where access to proper health care is limited. Pathogenesis of the characteristic painless ulcers is linked to the elaboration by M. ulcerans of a lipid toxin called mycolactone that has potent cytopathic, immunosuppressive, and analgesic effects on a host of cells in cutaneous tissues. Mycolactone is known to profoundly inhibit secretion of a plethora of proteins that are essential for wound healing. Even though a combination antibacterial therapy of streptomycin and rifampicin for 8 weeks is effective for treatment, it relies on good and appropriate wound management to prevent secondary bacterial infections and improve healing. Evidence-based interventions for wound care in Buruli ulcer disease are often lacking and have relied on expert advice and recommendations. Surgical interventions are limited to debridement of necrotic tissue and grafting of extensive ulcers, usually after antibiotic therapy. Patients’ rehabilitation is an important component of care to reduce disabilities associated with the disease and proper integration into the community after treatment.
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This comprehensive analysis outlines the recommended mental health services in HIV
care, delivery modalities, required resources, guideline integration, special population
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Mapping Report - Ireland.
Training module on malaria control
Guiding Principles for Feeding Infants and Young Children During Emergencies
recommended
WHO
(2004)
Tanzania Demographic and Health Survey
National Bureau of Statistics
inistry of Health and Social Welfare (MoHSW), Tanzania Food and Nutrition Centre (TFNC), et al.
(2011)
C1
WHO GUIDELINES REVIEW COMMITTEE
Guidance Note. The recommended actions are presented under the different components (water supply, hygiene and hand washing, disinfection, solid waste management, latrine and wastewater management,
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This guide provides practical, step-by-step guidance on how to organize, implement, and monitor community-based care for DR TB. It is equally useful for program planning or supervision. The target audience for this guide is TB Program Managers, gove
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rnments, policy makers, nongovernmental organizations (NGOs), donors and TB advocates.
This guide does not replace other guidelines and documents that contain important medical information, such as Guidelines for the Programmatic Management of Drug-resistant TB (WHO, 2008 and 2011 updates), and Management of MDR-TB: A Field Guide (WHO, 2009).
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Manual for the care and management of patients in Ebola Care Units/ Community Care Centres - Interim emergency guidance, January 2015
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World Health Organization
(2015)
This manual provides guidance on best practices to be followed in Ebola Care Units (ECUs)/Community Care Centres (CCCs). It is intended for health aid workers (including junior nurses and community health-care workers)
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Zika virus and potential complications: Questions and answers
World Health Organization (WHO)
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C_WHO
updated 05 April 2016