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2022 Global Atlas of Medical Devices

Velazquez Berumen, A.; S. Groth, G. Forte et al. World Health Organisation (WHO) (2022) C_WHO
The country profiles incorporate facts indicating the national status of medical devices in areas such as: medical device policies, regulations, incorporation, lists, inventories, nomenclature, health technology assessment, management, and biomedical engineering resources. This publication is int... more
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Dengue diagnostics: serious inaccuracies are likely to occur if pre-analytical conditions are not strictly followed

Campos de Meli Iani, F.; A.C. Barbosa Caetano, J.C. Wenceslau Cocovich et al. (2021) CC
Mem Inst Oswaldo Cruz . 2021 Jan 29;115:e200287. doi: 10.1590/0074-02760200287. eCollection 2021. Sensitivity and negative predictive value were directly affected by sample storage conditions. RT-PCR and virus isolation showed greater dependence on well-conserved samples for an accurate diagnosis
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WHF IASC Roadmap on Chagas Disease

Echeverría, L.; Marcus, R.; Novick, G. et al. WHF Global Heart (2020) CC
The WHF IASC Roadmap proposes strategies and evidence-based solutions for healthcare professionals, health authorities and governments to help overcome the barriers to comprehensive care for Chagas disease patients. This roadmap describes an ideal patient care pathway, and explores the roadblocks al... more
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The Chagas disease study landscape

Maguire, B.; Dahal, P.; Rashan, S. et al. PLoS Neglected Tropical Diseases (2021) CC
A systematic review of clinical and observational antiparasitic treatment studies to assess the potential for establishing an individual participant-level data platform. Chagas disease (CD), caused by the parasite Trypanosoma cruzi, affects ~6–7 million people worldwide. Significant limitations s... more
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Chagas Disease: From Discovery to a Worldwide Health Problem

Lidani, K.; Andrade, F.; Bavia, L. et al. Frontiers Public Health (2019) CC
Carlos Chagas discovered American trypanosomiasis, also named Chagas disease (CD) in his honor, just over a century ago. He described the clinical aspects of the disease, characterized by its etiological agent (Trypanosoma cruzi) and identified its insect vector. Initially, CD occurred only in Latin... more
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“We know about schistosomiasis but we know nothing about FGS”

Mazigo, H.; Sanson, A.; Lambert, V.; et al. (2021) CC
A qualitative assessment of knowledge gaps about female genital schistosomiasis among communities living in Schistosoma haematobium endemic districts of Zanzibar and Northwestern Tanzania. PloS Neglected Tropical Diseases September 30, 2021 https://doi.org/10.1371/journal.pntd.0009789 Schistosoma... more
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The Chagas disease study landscape: A systematic review of clinical and observational antiparasitic treatment studies

Maguire, B.; Dahal, P.; Rashan, S.; et al. (2021) CC
PLoS Neglected Tropical diseases August 16, 2021 https://doi.org/10.1371/journal.pntd.0009697 Chagas disease, also known as American trypanosomiasis, is a neglected tropical disease transmitted by triatomine insects, first identified in 1909. Chagas disease affects approximately 6–7 million peop... more
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Molecular and Clinical Aspects of Chronic Manifestations in Chagas Disease: A State-of-the-Art Review

Medina-Rincón, G.; Gallo-Bernal, S.; Jiménez, P.; et al. (2021) CC
Pathogens . 2021 Nov 16;10(11):1493.doi: 10.3390/pathogens10111493 .Chronic manifestations of Chagas disease present as disabling and life-threatening condi-tions affecting mainly the cardiovascular and gastrointestinal systems. Although meaningful research has outlined the different molecular mech... more
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Increasing access to comprehensive care for Chagas disease: development of a patient-centered model in Colombia

Marchiol, A; Forsyth, C.; Bernal, O.; et al. Pan American Health Organization PAHO (2017) C_WHO
Rev. Panam Salud Publica. 2017;41:e153. doi: 10.26633/RPSP.2017.153 Worldwide, over 6 million people are infected with Trypanosoma cruzi, the pathogen that causes Chagas disease (CD). In the Americas, CD creates the greatest burden in disability-adjusted life years of any parasitic infection. In Co... more
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Improving access to testing for Chagas disease in Colombia

Caicedo Díaz, RA,; Forsyth, C.; Bernal, OA; et al. Drugs for Neglected Diseases initiative DNDi (2019) CC
This is a summary of the following peer-reviewed, scientific article: Comparative Evaluation of Immunoassays to Improve Access to Diagnosis for Chagas Disease in Colombia.
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Diagnosis and Prevalence of Chagas Disease in an Indigenous Population of Colombia

Kann, S.; Dib, J.; Aristizabal, A.; et al. Multidisciplinary Digital Publishing Institute (2022) CC
Microorganisms . 2022 Jul 14;10(7):1427. Chagas disease (CD) is endemic in about 21 countries of the Americas. The disease has spread to recently Chagas-free regions, mainly due to migration, and can now also be diagnosed in countries such as the USA, Canada, many European and some African, eastern... more
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Diagnosis and Clinical Management of Chagas Disease
recommended

Suárez, C.; Nolder, D.; García-Mingo, A.; et al. (2022) CC
Research and Reports in Tropical Medicine 2022:13 25–40 Chagas disease (CD) or American trypanosomiasis is a neglected parasitic disease associated with significant mortality and morbidity that includes long-term disability, social stigma and a mental health toll. Perceived as a disease of the ve... more
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Chagas Disease: Detection of Trypanosoma cruzi by a New, High-Specific Real Time PCR

Kann, S.; Kunz, M.; Hansen, J.; et al. (2020) CC
J Clin Med . 2020 May 18;9(5):1517. doi: 10.3390/jcm9051517. Chagas disease (CD) is a major burden in Latin America, expanding also to non-endemic countries. A gold standard to detect the CD causing pathogen Trypanosoma cruzi is currently not available. Existing real time polymerase chain reaction... more
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Chagas disease: Current perspectives on a forgotten disease

Àlvarenz-Hernández, D.; Framyuti-Kelly, G.; Díaz-López-Silva, R.; et al. (2016) CC
Revista Médica del Hospital General de México, Vol. 81. Issue 3.Pages 154-164 (July - September 2018) Chagas disease is a parasitic zoonosis caused by Trypanosoma cruzi, a protozoan whose transmission to humans is primarily vector-borne. It is estimated that 6–8 million people worldwide are inf... more
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Modelling historical changes in the force-of-infection of Chagas disease to inform control and elimination programmes: application in Colombia

Cucunubá, Z.; Nouvellet, P.; Conteh, L. et al. BMJ Global Health (2022) CC
WHO's 2020 milestones for Chagas disease include having all endemic Latin American countries certified with no intradomiciliary Trypanosoma cruzi transmission, and infected patients under care. Evaluating the variation in historical exposure to infection is crucial for assessing progress and for und... more
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Health beliefs and health seeking behavior towards lymphatic filariasis morbidity management and disability prevention services in Luangwa District, Zambia: Community and provider perspectives

Maritim, P., A. Silumbwe, J.M. Zulu, et al. (2021) C2
Lymphatic filariasis (LF) infection if untreated results in fluid accumulation in the limbs or breasts (lymphedema) or genitalia (hydrocele) that is painful and causes great discomfort. Morbidity management and disability prevention (MMDP) strategies such as surgery for hydrocele, treatment of acute... more
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Healthcare Workers’ Knowledge about Chagas Disease: A Systematic Review

Monteiro Soares Cajaiba-Soares, A.; M.S. Martinez-Silveira, D. Lopes Paim Miranda,et al. (2021) C2
Transmission of Chagas disease (CD) has decreased in recent decades, but the disease remains an important problem in endemic areas. There was an increase in the proportion of nonvector transmission, mainly in nonendemic countries. The aim of this study was to gather evidence concerning healthcare pr... more
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Prevalence and distribution of schistosomiasis in human, livestock, and snail populations in northern Senegal: a One Health epidemiological study of a multi-host system

Léger, E.; Borlase, A.; Fall, C. et al. The Lancet Planetary Health (2020) CC
Schistosomiasis is a neglected tropical disease of global medical and veterinary importance. As efforts to eliminate schistosomiasis as a public health problem and interrupt transmission gather momentum, the potential zoonotic risk posed by livestock Schistosoma species via viable hybridisation in s... more
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Male Genital Schistosomiasis Along the Shoreline of Lake Malawi: Baseline Prevalence and Associated Knowledge, Attitudes and Practices Among Local Fishermen in Mangochi District

Kayuni, S.; Alharbi, M.; Makaula, P. et al frontiers in Public Health (2021) CC
Schistosomiasis is a prevalent parasitic, neglected tropical disease (NTD) affecting over 220 million people globally, especially in sub-Saharan Africa (SSA). The pathology of this disease in terms of intestinal, liver and urinary presentations is well-known, yet its chronic effect on host genitalia... more
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Cervicovaginal Immune Activation in Zambian Women With Female Genital Schistosomiasis

Sturt, A.; Webb, E.; Patterson, C.; et al. Frontiers Media S.A. (2021) CC
HIV-1 infection disproportionately affects women in sub-Saharan Africa, where areas of high HIV-1 prevalence and Schistosoma haematobium endemicity largely overlap. Female genital schistosomiasis (FGS), caused most frequently by S. haematobium egg deposition in the genital tract, has been associated... more