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Guidelines for diagnosing, preventing and managing cryptococcal disease among adults, adolescents and children living with HIV. Policy brief
recommended

World Health Organization WHO (2022) C_WHO

Cryptococcal disease, particularly cryptococcal meningitis is a significant cause of morbidity and mortality among people living with HIV with advanced HIV disease. It is estimated that it is responsible for nearly 19% of AIDS-related mortality, second only to tuberculosis. Rapid screening, diagnosi... more

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Treatment of Mycobacterium Ulcerans Disease (Buruli Ulcer)
recommended

World Health Organization WHO WHO (2012) C_WHO

Guidance for health workers

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Corticosteroids for COVID-19

World Health Organization WHO (2020) C_WHO

WHO published guidance for clinicians and health care decision-makers on the use of corticosteroids in patients with COVID-19. We recommend systemic corticosteroids for the treatment of patients with severe and critical COVID-19. We suggest not to use corticosteroids in the treatment of patients ... more

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Management of Tuberculosis in Children - Manual for Health Care Workers

Ministry of Health and Social Welfare, The United Republic of Tanzania (2012) C1

National Tuberclosis and Leprosy Programme (NTLP)

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Health Sector Development Programme IV 2010/11 – 2014/15

Federal Democratic Republic of Ethiopia Ministry of Health (2010) C1

External Link

Recommendations of the German Central Committee against Tuberculosis (DZK) and the German Respiratory Society (DGP) for the Diagnosis and Treatment of Non-tuberculous Mycobacterioses

N. Schoenfeld, W. Haas, E. Richter, et al. (2016) C2

Empfehlungen zur Diagnostik und Therapie nichttuberkulöser Mykobakteriosen des Deutschen Zentralkomitees zur Bekämpfung der Tuberkulose (DZK) und der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin (DGP). Schönfeld N et al. Recommendations of the German Central Committee… Pneumolo... more

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South Sudan Health Cluster Bulletin 12, December 2018

World Health Organization, Health Cluster (2019) C_WHO

Emergency WASH in Health Facilities in Conflict Affected Locations 756 health workers trained on disease surveillance and outbreak response. Around 142 health workers trained on integrated health (WASH and Nutrition) response. 405 health facilities are equipped with functional incinerators. Qual... more

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Central Medical Stores Botswana 2010 – 2012 Strategic Plan

Thomson, D., Shivanandan, J. &; Brown, T. Ministry of Health, Botswana; PEPFAR; SCMS (2010)

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First Ethiopian National Population Based Tuberculosis Prevalence Survey

Ministry of Health and Ethiopian Health and Nutrition Research Institute, Federal Democratic Republic of Ethiopia (2011) C1

External Link

TB financing in East Europe promotes unnecessary hospital admissions: the case of Armenia

Gillini, L.; K. Davtyan, H. Davtyan, et al. (2013) C2

The Journal of Infection in Developing Countries 7(3):289-292

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Plausible role for CHW peer support groups in increasing care-seeking in an integrated community case management project in Rwanda: a mixed methods evaluation

Langston, A., Weiss, J., Landegger, J., et al. Global Health: Science and Practice (2014) CC

The Kabeho Mwana project (2006–2011) supported the Rwanda Ministry of Health (MOH) in scaling up integrated community case management (iCCM) of childhood illness in 6 of Rwanda’s 30 districts. The project trained and equipped community health workers (CHWs) according to national guidelines. In p... more

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Pediatric delirium - A practical approach

J. N. M. Schieveld; E. Ista; H. Knoester; et al. IACAPAP (2015) C2

Psychiatry and Pediatrics Chapter I.5

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WHO Monographs On Selected Medicinal Plants - Volume 4
recommended

World Health Organization WHO (2009) C_WHO

• provide scientific information on the safety, efficacy, and quality control/ quality assurance of widely used medicinal plants, in order to facilitate their appropriate use in Member States; • provide models to assist Member States in developing their own mono- graphs or formularies for these... more

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National Tuberculosis and Leprosy Control Strategic Plan

Government of Malawi; Ministry of Health Malawi (2024) CC2

Malawi is a landlocked country with a surface area of 118,484 km2. Administratively, the country is divided into three regions, namely the Northern, Central and Southern regions. The country has 28 districts, which are further divided into traditional authorities (TA) ruled by chiefs. The TAs are su... more

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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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Guidelines for antiretroviral therapy in Ghana

Ghana AIDS Commission (2010) C1

External Link

Novel vaccination approaches to prevent tuberculosis in children

J. A. Triccas, C. Counoupas Pneumonia; BioMed Central (2016) CC

Review Triccas and Counoupas Pneumonia (2016) 8:18; DOI 10.1186/s41479-016-0020-z

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African Union AMR Landmark Report: Voicing African Priorities on the Active Pandemic

Africa Center for Disease Control and Prevention (2024) CC

Antimicrobial resistance (AMR) has emerged as a leading cause of death in the African region, surpassing fatalities from malaria, HIV, and TB. In response to this critical threat, the region has adopted the AMR Global Action Plan and the African Union Framework for Antimicrobial Resistance Control 2... more

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Ethical considerations for use of unregistered interventions for Ebola viral disease

World Health Organization (2014)

West Africa is experiencing the largest, most severe, most complex outbreak of Ebola virus disease in history. On 11 August 2014, WHO convened a consultation where the participants concluded that in the particular context of the current Ebola outbreak in West Africa, it is ethically acceptable to of... more

Guidelines for diagnosing, preventing and managing cryptococcal disease among adults, adolescents and children living with HIV. Policy brief recommended

Treatment of Mycobacterium Ulcerans Disease (Buruli Ulcer) recommended

WHO Monographs On Selected Medicinal Plants - Volume 4 recommended

Guidelines for diagnosing, preventing and managing cryptococcal disease among adults, adolescents and children living with HIV. Policy brief
recommended

Treatment of Mycobacterium Ulcerans Disease (Buruli Ulcer)
recommended

WHO Monographs On Selected Medicinal Plants - Volume 4
recommended