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Global Morbidity and Mortality of Leptospirosis: A Systematic Review

Costa, F.; Hagan, J.; Calcagno, J. PLoS Neglected Tropical diseases (2015) CC

Leptospirosis, a spirochaetal zoonosis, occurs in diverse epidemiological settings and affects vulnerable populations, such as rural subsistence farmers and urban slum dwellers. Although leptospirosis is a life-threatening disease and recognized as an important cause of pulmonary haemorrhage syndrom... more

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HEARTS. Technical package for cardiovascular disease management in primary health care.

World Health Organization WHO (2016) C_WHO

The HEARTS technical package provides a strategic approach to improving cardiovascular health in countries. It comprises six modules and an implementation guide. This package supports Ministries of Health to strengthen CVD management in primary health care settings. The practical, step-by step modul... more

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The malaria testing and treatment landscape in Benin

Zinsou, C.; A. Bello Cherifath ACT Watch Group et al (2017) C1

Malar J (2017) 16:174 DOI 10.1186/s12936-017-1808-x Background: Since 2004, artemisinin-based combination therapy (ACT) has been the first-line treatment for uncomplicated malaria in Benin. In 2016, a medicine outlet survey was implemented to investigate the availability, price, and market share of... more

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COVID-19 pandemic in the health of women, children, and adolescents in Latin America and the Caribbean

Castro, A. UNDP (2020) CC

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Substance abuse treatmentand care for women: Case studies and lessons learned

United Nations Office on Drugs and Crime (UNODC) (2004) C1

The present booklet is about gender-responsive substance abuse treatment services for women. It is part of the United Nations Office on Drugs and Crime (UNODC) project to develop tools to support the development and improvement of substance abuse treatment services, based on evidence from the litera... more

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A review of the available therapeutic agents that target the different steps of the ebola virus life cycle

Kang Yiu Lai, Wing Yiu George Ng and Fan Fanny Cheng (2014)

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Guideline for the treatment of women undergoing termination of pregnancy

Dutch Association of Abortion Specialists (NGvA) (2011) C2

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Access to NCD medicines: emergent issues during the COVID-19 pandemic and key structural factors 2023

World Health Organization WHO (2023) C_WHO

The coronavirus disease (COVID-19) pandemic exacerbated pre-existing inequalities in the treatment and care of noncommunicable diseases (NCDs). This report examines the effect of the COVID-19 pandemic on access to NCD medicines, and the policies and strategies implemented by countries and health sys... more

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Dry Eye Disease. Screening, Diagnosis, Assessment and Management of Dry Eye Disease in India. Full Background document (draft)

National Health Mission; Ministry of Health & Social Welfare India (2016) C1

Standard Treatment Guideline

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Responsible use of antibiotics in aquaculture

Hernández Serrano, P. Food and Agriculture Organization (FAO) (2005) C2

In aquaculture, antibiotics have been used mainly for therapeutic purposes and as prophylactic agents. The contribution to antimicrobial resistance of antibiotics used in aquaculture is reviewed here, using a risk analysis framework. Some recommendations on responsible conduct in this context are pr... more

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Evaluation involvement of local HIV/AIDS nongovernmental organisations in Benin

Maurice T. Agonnoude, François Champagne, Nicole Leduc African Evaluation Journal (2016) C2

African Evaluation Journal ISSN: (Online) 2306-5133, (Print) 2310-4988 Background: For some years, non-governmental organisations (NGOs) and civil society have become increasingly involved in the fight against the HIV/AIDS pandemic in Africa. But even though their role is well appreciated, the... more

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Field Trials of Health Interventions: A Toolbox

Peter G. Smith, Richard H. Morrow, and David A. Ross (2015)

This version of Field Trials of Health Interventions includes seven new chapters on conducting systematic literature reviews, trial governance, preliminary studies and pilot testing, budgeting and accounting, intervention costing and economic analysis, and Phase IV studies. Before new interventions... more

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Understanding modelling approaches for sexual, reproductive, maternal, newborn, child and adolescent health, and nutrition

World Health Organization WHO; UNICEF and UNFPA (2021) C_WHO

Modelling the health impacts of disruptions to essential health services during COVID-19 Module 1 Several epidemiological models have been created to assess the potential impact of disruptions to essential health services caused by COVID-19 on morbidity and mortality from conditions other than COVI... more

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Infrastructure, policy and regulatory interventions to increase physical activity to prevent cardiovascular diseases and diabetes: a systematic review

Durão, S.; Burns, J.; Schmidt, B. et al. BMC Public Health (2023) CC

Background Noncommunicable diseases are major contributors to morbidity and mortality worldwide. Modifying the risk factors for these conditions, such as physical inactivity, is thus essential. Addressing the context or circumstances in which physical activity occurs may promote physical activity a...t a population level. We assessed the effects of infrastructure, policy or regulatory interventions for increasing physical activity. Methods We searched PubMed, Embase and clinicaltrials.gov to identify randomised controlled trials (RCTs), controlled before-after (CBAs) studies, and interrupted time series (ITS) studies assessing population-level infrastructure or policy and regulatory interventions to increase physical activity. We were interested in the effects of these interventions on physical activity, body weight and related measures, blood pressure, and CVD and type 2 diabetes morbidity and mortality, and on other secondary outcomes. Screening and data extraction was done in duplicate, with risk of bias was using an adapted Cochrane risk of bias tool. Due to high levels of heterogeneity, we synthesised the evidence based on effect direction. Results We included 33 studies, mostly conducted in high-income countries. Of these, 13 assessed infrastructure changes to green or other spaces to promote physical activity and 18 infrastructure changes to promote active transport. The effects of identified interventions on physical activity, body weight and blood pressure varied across studies (very low certainty evidence); thus, we remain very uncertain about the effects of these interventions. Two studies assessed the effects of policy and regulatory interventions; one provided free access to physical activity facilities and showed that it may have beneficial effects on physical activity (low certainty evidence). The other provided free bus travel for youth, with intervention effects varying across studies (very low certainty evidence). Conclusions Evidence from 33 studies assessing infrastructure, policy and regulatory interventions for increasing physical activity showed varying results. The certainty of the evidence was mostly very low, due to study designs included and inconsistent findings between studies. Despite this drawback, the evidence indicates that providing access to physical activity facilities may be beneficial; however this finding is based on only one study. Implementation of these interventions requires full consideration of contextual factors, especially in low resource settings. more

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Kenya Verbal Autopsy Standards & Guidelines

Ministry of Health, Kenya (2019) C1

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Лекарственная терапия при COVID-19

World Health Organization WHO (2021) C_WHO

Вариативные рекомендации 24 сентября 2021 г. Этот документ представляет собой текущие рекомендации ВОЗ. В них будут вноситься изменения и дополнения, касающиеся нов... more

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Water, sanitation and hygiene in health care facilities: status in low and middle income countries and way forward.

Maria Neira, Edward Kelley, Mickey Chopra et al. World Health Organization, UNICEF (2015)

This report presents, for the first time, a global assessment of the extent to which health care facilities provide essential water, sanitation and hygiene (WASH) services. Drawing on data from 54 low- and middle-income countries, the report concludes that 38% lack access to even rudimentary levels ... more

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Global Accelerated Action for the Health of Adolescents (AA-HA!): guidance to support country implementation, second edition.

World Health Organization WHO (2023) C_WHO

The World Health Organization (WHO) is releasing the second edition of its Global Accelerated Action for the Health of Adolescents (AA-HA!) guidance. The document aims to equip governments to respond to the health and well-being challenges, opportunities and needs of adolescents. The guidance pro... more

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Multimorbidity. Technical Series on Safer Primary Care

World Health Organization WHO (2016) C_WHO

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Impact of climate change on human infectious diseases: Empirical evidence and human adaptation

Xiaoxu Wu, Yongmei Lu, Sen Zhou et al. (2016) CC

Environment International Volume 86, January 2016, Pages 14-23 Climate change refers to long-term shifts in weather conditions and patterns of extreme weather events. It may lead to changes in health threat to human beings, multiplying existing health problems. This review examines the scientific e... more