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Not all that bleeds is Ebola
recommended

International Rescue Committee (2020) C1
How has the DRC Ebola outbreak impacted Sexual and Reproductive Health in North-Kivu? Recommendations (more specifics found in the assessment): 1. Sexual and reproductive health needs and services are to be embedded in the EVD response from the outset. 2. Reduce delays at every stage of the patie... more
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Interim Guidelines on Management of COVID-19 in Kenya - COVID-19, Infection Prevention and Control (IPC) and Case Management

Dr. P. Amoth; Dr. S. K. Kibias Ministry of Health; University of Nairobi (2020) C2
Accessed: 02.05.2020 These consolidated guidelines provide recommendations for comprehensive prevention and case management strategies in Kenya Scope of the Guidelines: Infection prevention and control Patient triage Emergency Medical Services Case management Laboratory testing algorithm Target... more
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Clinical care for severe acute respiratory infection: toolkit: COVID-19 adaptation
recommended

World Health Organization WHO (2022) C_WHO
First published in 2020, this toolkit is intended for clinicians working in acute care, managing adult and paediatric patients with acute respiratory infection, including severe pneumonia, acute respiratory distress syndrome, sepsis and septic shock. The main objective is to provide key tools for us... more
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Solidarity” clinical trial for COVID-19 treatments

World Health Organization WHO (2020) CC
Solidarity” is an international clinical trial to help find an effective treatment for COVID-19, launched by the World Health Organization and partners. The Solidarity Trial will compare four treatment options against standard of care, to assess their relative effectiveness against COVID-19. By... more
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Interim Guidance: Gender Alert for COVID-19 Outbreak

Inter-Agency Standing Committee IASC, et al. (2020) C1
Recognizing the extent to which the COVID-19 outbreaks affects women and men differently is hugely important. Some preliminary data suggested that more men than women are dying, potentially due to sex-based immunological differences, higher rates of cardiovascular disease for men and lifestyle choic... more
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RAPID CORE CRF Completion Guidance
recommended

World Health Organization WHO (2020) C_WHO
DESIGN OF THIS CASE REPORT FORM (CRF)This CRF has 3 modules:Module 1to be completed on the first day of admission to the health centre.Module 2 to be completed daily during hospital stay for as many days as resources allow. Continue to follow-up patients who transfer between wards. Module 3 to be co... more
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Quick guide to video-supported treatment of tuberculosis (2020)

World Health Organization WHO, Regional Office of Europe (2020) C_WHO
Despite being a curable and preventable disease, tuberculosis (TB) remains as one of the major challenges for health systems, globally. Every year, TB affects more than 10 million people and kills more than 1.4 million people. WHO’s Digital Health for the End TB Strategy – an Agenda for Action o... more
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Therapeutics and COVID-19: living guideline, Updated 16 September 2022
recommended

World Health Organization WHO (2022) C_WHO
This twelfth version of the WHO living guideline now contains 19 recommendations. This latest update provides updated recommendations for remdesivir, addresses the use of combination therapy with corticosteroids, interleukin-6 (IL-6) receptor blockers and Janus kinase (JAK) inhibitors in patients wi... more
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African Union Framework for Antimicrobial Resistance Control 2020–2025
recommended

African Union; Africa CDC Centres for Disease Control and Prevention; World Health Organization WHO, et al. (2021) CC
Reports of antimicrobial-resistant (AMR) microorganisms are increasing globally, threatening to render existing treatments ineffective against many infectious diseases. In Africa, AMR has already been documented to be a problem for human immunodeficiency virus (HIV) and the pathogens that cause mala... more
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Utilisation des masques médicaux et non médicaux/en tissu dans le cadre des activités de santé à base communautaire pendant la pandémie de COVID-19
recommended

World Health Organization WHO (2021) C_WHO
sur la base des orientations actuelles de l’OMS, 31 may 2021. Aide mémoire This aide-mémoire presents information on use and procurement of masks for community outreach interventions, with a focus on those for malaria, neglected tropical diseases, tuberculosis, HIV/AIDS and vaccine-preventable ... more
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A clinical case definition of post COVID-19 condition by a Delphi consensus, 6 October 2021
recommended

World Health Organization WHO (2021) C_WHO
WHO has developed a clinical case definition of post COVID-19 condition by Delphi methodology that includes 12 domains, available for use in all settings. This first version was developed by patients, researchers and others, representing all WHO regions, with the understanding that the definition ma... more
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Essential Emergency and Critical Care: a consensus among global clinical experts

Schell, C.O.; K. Khalid, A.Wharton-Smith, et al. (2021) CC
Key questions What is already known? Critical illness is common throughout the world and COVID-19 has caused a global surge of critically ill patients. There are large gaps in the quality of care for critically ill patients, especially in low-staffed and low-resourced settings, and mortal... more
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JOIN European First Aid Guidelines
recommended

Johanniter International (2022) C2
In the event of an accident or medical emergency, First Aid saves lives. Keeping the patient alive and safe until the arrival of expert professional help is a vital part of the chain of care which leads to recovery. The principle of First Aid must be simple skills, clearly taught and capable of bein... more
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Therapeutics for Ebola virus disease
recommended

World Health Organization WHO (2022) C_WHO
The WHO Ebola Virus Disease (EVD) Clinical management: living guidance contains the Organization’s most up-to-date recommendations for the clinical management of people with EVD. Providing guidance that is comprehensive and holistic for the optimal care of patients with EVD throughout their il... more
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Quality and safety practices for malaria rapid testing services

World Health Organization WHO (2022) C_WHO
This document is a guide defining requirements for quality and safety for malaria rapid diagnostic testing services to safeguard the quality of the results, the safety of the operators and patients and that of the environment for use by national malaria control programmes, regulators, implementers a... more
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Buruli ulcer : management of Mycobacterium ulcerans disease : a manual for health care providers

J. Buntine; Crofts, K. World Health Organization WHO (2001) CC
This manual is addressed to health care providers dealing with Mycobacterium ulcerans disease (Buruli ulcer). The manual aims to achieve a better understanding of the disease, its clinical presentation and its surgical management. The manual is aimed particularly at district health care providers. A... more
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Acute Chagas Disease: New Global Challenges for an Old Neglected Disease

Andrade, D.; Gollob, K.; Dutra, W. PLoS Neglected Tropical diseases (2015) CC
Abstract: Chagas disease is caused by infection with the protozoan Trypanosoma cruzi, and although over 100 years have passed since the discovery of Chagas disease, it still presents an increasing problem for global public health. A plethora of information concerning the chronic phase of human Chaga... more
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Efficacy and Safety of Pafuramidine versus Pentamidine Maleate for Treatment of First Stage Sleeping Sickness in a Randomized, Comparator-Controlled, International Phase 3 Clinical Trial

Pohlig G, Bernhard SC, Blum J, Burri C, Mpanya A, et al. PLOS Neclected Tropical Diseases (2016) CC
This was a Phase 3, multi-center, randomized, open-label, parallel-group, active control study where 273 male and female patients with first stage Trypanosoma brucei gambiense HAT were treated at six sites: one trypanosomiasis reference center in Angola, one hospital in South Sudan, and four hospita... more
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The Challenges of Conducting Clinical Research on Neglected Tropical Diseases in Remote Endemic Areas in Sudan

El-Safi, S.; Chappuis, F.; Boelaert, M. PLoS Neglected Tropical diseases (2016) CC
Most neglected tropical diseases (NTDs) occur in remote areas of low- and middle-income countries, where health systems are often poorly developed. Therefore, these neglected patients generally lack access to quality preventive, diagnostic, and therapeutic care [1]. The difficulty to access NTD-ende... more
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South Africa’s capacity to conduct antimicrobial stewardship

Chetty, S. Southern African Journal of Infectious Diseases (2021) CC
Antimicrobial resistance (AMR) as a serious public health threat was globally acknowledged by WHO in 2015, through the launch of the Global Action Plan (GAP). With a limited number of new antibiotics in the developmental pipeline, many countries are in the process of establishing strategies for anti... more