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When the Drugs Don’t Work – Antibiotic Resistance as a Global Development Problem

The Dag Hammarskjöld Foundation and ReAct (2019) C2

This paper focuses on the Sustainable Development Goals related to poverty, economic growth, inequality, health, food production and the environment. It presents concrete examples of the underlying and complex aspects of antibiotic resistance and its impacts across different Sustainable Development ... more

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National Guidelines for the Treatment of Malaria, South Africa 2019

National Department of Health, South Africa (2019) C1

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Kerala Antimicrobial Resistance Strategic Action Plan (KARSAP)

Department of Agriculture Development & Farmers Welfare; Health & Family Welfare, Government of Kerala (2018) C1

One health Response to AMR Containment. In a significant move for the public health sector, Kerala has become the first state in India to launch an action plan to combat the growing cases of antimicrobial immunity, arising primarily from irrational use of medicines and excessive antibiotics used in... more

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National Programme for Prevention and Control of Diabetes, Cardiovascular Disease and Stroke

World Health Organization WHO (2019) C_WHO

A Manual for Medical Officer Developed under the Government of India – WHO Collaborative Programme 2008-2009 Accessed: 11.03.2019

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2019 Antibacterial agents in clinical development: an analysis of the antibacterial clinical development pipeline
recommended

World Health Organization WHO (2019) C_WHO

Of the 50 antibiotics in the pipeline, 32 target WHO priority pathogens but the majority have only limited benefits when compared to existing antibiotics. Two of these are active against the multi-drug resistant Gram-negative bacteria, which are spreading rapidly and require urgent solutions. Gr... more

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Checking in on the Checklist

Buissonniere, M. Lifebox and Ariadne Labs (2019) CC

The report and an accompanying series of studies show the global uptake of the World Health Organization (WHO) Surgical Safety Checklist in its first ten years since its launch and recommend ways the Checklist can be more effectively used to improve surgical safety for millions at risk. The report ... more

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Monitoring and Evaluation of the Global Action Plan on Antimicrobial Resistance: framework and recommended indicators

World Health Organization (WHO), Food and Agriculture Organization of the United Nations (FAO) and World Organisation for Animal Health (OIE) (2019) C_WHO

The GAP articulates five objectives for tackling AMR, and sets out the tasks required to achieve them, highlighting roles and responsibilities for country governments, the One Health Tripartite organizations (FAO, OIE and WHO) and other national and international partners. To ensure that all stakeh... more

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Joint FAO/WHO Expert Meeting in collaboration with OIE on Foodborne Antimicrobial Resistance: Role of the Environment, Crops and Biocides

World Health Organization WHO, Food and Agriculture Organization of the United Nations FAO (2019) C_WHO

In recognition of the growing problem of antimicrobial resistance (AMR), its increasing threat to human, animal and plant health, and the need for a One Health approach to address this issue, the 39th Session of the Codex Alimentarius Commission (CAC) agreed it was important for the food safety comm... more

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Tackling antimicrobial use and resistance in pig production: lessons learned in Denmark

Food and Agriculture Organization of the United Nations FAO (2019) C2

This publication describes an arduous campaign to tackle the use of antimicrobials - specifically antibiotics - in the Danish swine-producing sector thanks to the collaboration between the regulatory sector within the Ministry of Environment and Food, private veterinary practitioners and swine produ... more

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Guidelines for the Prevention and Containment of Antimicrobial Resistance in South African Hospitals

National Department of Health South Africa (2019) C2

These guidelines form part of efforts to institutionalise the prevention and containment of antimicrobial resistance (AMR) in health care facilities in South Africa, as outlined in the Antimicrobial Resistance Strategic Framework and Implementation Plan. The focus of these guidelines is on two inte... more

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Antimicrobial stewardship programmes in health-care facilities in low- and middle-income countries. A WHO practical toolkit

World Health Organization WHO (2019) C_WHO

Stewardship is defined as “the careful and responsible management of something entrusted to one’s care”. It was originally applied in the health-care setting as a tool for optimizing antimicrobial use, termed “antimicrobial stewardship” (AMS). Stewardship has since be... more

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Antibiotic Stewardship - From Principles to Practice / Ebook

British Society for Antimicrobial Chemotherapy BSAC (2019) C2

This book provides significantly expanded content and experience in relation to a broader stewardship context- for example, stewardship in specific populations, different countries as well as the role of different professions in stewardship to political and media engagement. We hope this book has so... more

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The Core Elements of Hospital Antibiotic Stewardship Programs: 2019

Centers for Disease Control and Prevention CDC (2019) C_CDC

This document updates the 2014 Core Elements for Hospital Antibiotic Stewardship Programs and incorporates new evidence and lessons learned from experience with the Core Elements. The Core Elements are applicable in all hospitals, regardless of size. There are suggestions specific to small and criti... more

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The Core Elements of Outpatient Antibiotic Stewardship

Centers for Disease Control and Prevention CDC (2019) C_CDC

The Core Elements of Outpatient Antibiotic Stewardship provides a framework for antibiotic stewardship for outpatient clinicians and facilities that routinely provide antibiotic treatment. This report augments existing guidance for other clinical settings. In 2014 and 2015, respectively, CDC release... more

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Tuberculosis Results Profile Ethiopia 2019

The Global Fund (2019) CC

Tuberculosis cases, TB deaths

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Management of the sick young infant aged up to 2 months. Chart booklet
recommended

World Health Organization WHO (2019) C_WHO

Integrated management of childhood illness. The last update was in the IMCI chart booklet in 2014, but since then there have been significant updates on the management of sick young infant (SYI) aged up to 2 months. This 2019 update of the sick young infant section Management of the sick young infan... more

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Management of the sick young infant aged up to 2 months. Participant Manual
recommended

World Health Organization WHO (2019) C_WHO

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Management of the sick young infant aged up to 2 months. Facilitator Guide
recommended

World Health Organization WHO (2019) C_WHO

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Government policy interventions to reduce human antimicrobial use: A systematic review and evidence map

Van Katwyk, S. R.; Grimshaw, J. M.; et al (2019) C2

BACKGROUND: Growing political attention to antimicrobial resistance (AMR) offers a rare opportunity for achieving meaningful action. Many governments have developed national AMR action plans, but most have not yet implemented policy interventions to reduce antimicrobial overuse. A systematic evidenc...e map can support governments in making evidence-informed decisions about implementing programs to reduce AMR, by identifying, describing, and assessing the full range of evaluated government policy options to reduce antimicrobial use in humans. METHODS AND FINDINGS: Seven databases were searched from inception to January 28, 2019, (MEDLINE, CINAHL, EMBASE, PAIS Index, Cochrane Central Register of Controlled Trials, Web of Science, and PubMed). We identified studies that (1) clearly described a government policy intervention aimed at reducing human antimicrobial use, and (2) applied a quantitative design to measure the impact. We found 69 unique evaluations of government policy interventions carried out across 4 of the 6 WHO regions. These evaluations included randomized controlled trials (n = 4), non-randomized controlled trials (n = 3), controlled before-and-after designs (n = 7), interrupted time series designs (n = 25), uncontrolled before-and-after designs (n = 18), descriptive designs (n = 10), and cohort designs (n = 2). From these we identified 17 unique policy options for governments to reduce the human use of antimicrobials. Many studies evaluated public awareness campaigns (n = 17) and antimicrobial guidelines (n = 13); however, others offered different policy options such as professional regulation, restricted reimbursement, pay for performance, and prescription requirements. Identifying these policies can inform the development of future policies and evaluations in different contexts and health systems. Limitations of our study include the possible omission of unpublished initiatives, and that policies not evaluated with respect to antimicrobial use have not been captured in this review. CONCLUSIONS: To our knowledge this is the first study to provide policy makers with synthesized evidence on specific government policy interventions addressing AMR. In the future, governments should ensure that AMR policy interventions are evaluated using rigorous study designs and that study results are published. more

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National Guidelines for the Treatment of Malaria - 2019

South African Malaria Elimination Committee (SAMC) National Department of Health South Africa (2019) CC

These guidelines are based on the 3rd Edition of the WHO Guidelines (Published 2015) World Health Organization’s Guidelines for the treatment of malaria. Additional literature surveys have been undertaken. Factors that were considered in the choice of therapeutic options included effectiveness, sa... more

2019 Antibacterial agents in clinical development: an analysis of the antibacterial clinical development pipeline recommended

Management of the sick young infant aged up to 2 months. Chart booklet recommended

Management of the sick young infant aged up to 2 months. Participant Manual recommended

Management of the sick young infant aged up to 2 months. Facilitator Guide recommended

2019 Antibacterial agents in clinical development: an analysis of the antibacterial clinical development pipeline
recommended

Management of the sick young infant aged up to 2 months. Chart booklet
recommended

Management of the sick young infant aged up to 2 months. Participant Manual
recommended

Management of the sick young infant aged up to 2 months. Facilitator Guide
recommended