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The Guidelines for the Prevention and Treatment of Opportunistic Infections in Adults and Adolescents With HIV document is published in an electronic format and updated as relevant changes in prevention and treatment recommendations occur.
Full Guidelines
IAS–USA Topics in Antiviral Medicine. September 22, 2025
Tuberculosis (TB) remains a serious public health threat in South Africa and is the leading cause of death in people living with HIV (PWH). Pre-hospital and early in- hospital mortality is of particular concern in PWH. Significant progress has been made to date, but a monumental effort is require ... more
These 2025 guidelines respond to the need for better approaches to identify advanced HIV disease, improve the poor outcomes of people living with HIV being discharged from hospital and provide updated guidance for treatment for Kaposi’s sarcoma through evidence-informed recommendations. The public ... more
Core Guidance. Differentiated service delivery is highlighted as a key approach for HIV programmes to enhance implementation quality and efficiency.
Essential triple EMTCT services include testing for HIV, syphilis and HBV in ante- natal care (ANC) settings; prompt and efficacious interventions to treat women who test positive; prevent transmission of any of the infections to their children; counseling for women and their partners to reduce t ... more

Prevention of mother-to-child transmission of HIV

Le Saout, E. International MSF HIV working Group (2020) C2
Internal Document
Prevention of mother-to-child HIV transmission (PMTCT) has been a success in many respects but there is still much to do to eliminate mother-to child transmission (MTCT), particularly in low antiretroviral therapy (ART) coverage areas and in the postnatal phase. The success of PMTCT is highly dep ... more
The adopted pillars for the AEVT Plan are a) early testing among children exposed to HIV, syphilis and HBV; b) closing the treatment gap among PBFW and children exposed to HIV, syphilis and HBV; c) prevention of new HIV, syphilis and HBV infections among PBFW; and d) breaking down barriers to access ... more
Les piliers adoptés pour le plan AEVT sont les suivants : a) dépistage précoce chez les enfants exposés au VIH, à la syphilis et au VHB ; b) réduction des inégalités en matière de traitement chez les PBFW et les enfants exposés au VIH, à la syphilis et au VHB ; c) prévention des nouvelle ... more
Pathogens 2022, 11, 33. https://doi.org/10.3390/pathogens11010033
the Pocket Guide includes information on HIV clinical care; growth and development; mental health; child protection; counselling and communication; disclosure; loss, grief, and bereavement; adherence; sexual and reproductive health; transition of care; support systems; and monitoring and evaluati ... more
a comprehensive guide for the HCPs who work in counselling and psychological care of children and adoles- cents. The Handbook includes information on HIV clinical care; growth and development; mental health; child protection; counselling and communication; disclosure; loss, grief, and bereavemen ... more
The Guide on HIV Services for Adolescents Living with HIV (ALHIV) describes organization of adolescent-friendly services to guide heath management teams and health care workers (HCWs) on their roles. It also outlines important aspects to consider when offering comprehensive care to adolescents an ... more
International Journal of Integrated Care, 2025; 25(2): 5, 1–12. DOI: https://doi.org/10.5334/ijic.8920. Community-based intervention support plays a crucial role in enhancing the lives of orphans and vulnerable children in Africa. Community-based intervention support needs to be integrated into ... more
A job aid for cadres supporting caregivers of children and adolescents living with HIV (ages 0-14) in Orphans and Vulnerable Children (OVC) Programs
Ces orientations opérationelles ont pour but de soutenir les pays dans le processus d’introduction d’un antibiotique. Leur objectif est de garantir un accès rapide aux antimicrobiens et l’utilisation appropriée de ces produits ainsi que des résultats optimaux pour les patients, tout en ré ... more
The family-centered approach to reaching every child living with HIV. This report examines the structural barriers impeding equitable access to HIV testing, treatment initiation and long-term adherence – essential elements for sustaining health and well-being for children, adolescents and young wo ... more
Progress report and road map. Countries included in this report: Algeria, Afghanistan, Bahrain, Djibouti, Egypt, the Islamic Republic of Iran, Iraq, Jordan, Kuwait, Lebanon, Libya, Morocco, Oman, Pakistan, Qatar, State of Palestine, Saudi Arabia, Somalia, Sudan, the Syrian Arab Republic, Tunisia, Un ... more