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Effectiveness of community health worker training programmes for cardiovascular disease management in low-income and middle-income countries: a systematic review

Abdel-All, M; Putica, B.; Praveen, D. et al. BMJ Open (2017) CC

Introduction Community health workers (CHWs) are increasingly being tasked to prevent and manage cardiovascular disease (CVD) and its risk factors in underserved populations in low-income and middle-income countries (LMICs); however, little is known about the required training necessary for them to ... more

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The link between the West African Ebola outbreak and health systems in Guinea, Liberia and Sierra Leone: a systematic review

Haitham Shoman, Emilie Karafillakis and Salman Rawaf (2017) CC

Shoman et al. Globalization and Health (2017) 13:1 DOI 10.1186/s12992-016-0224-2

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The availability, cost, and affordability of essential medicines for asthma and COPD in low-income and middle-income countries: a systematic review

Stolbrink, M.; Thomson, H.; Hadfield, R.M. et al. The Lancet Global Health (2022) CC

Background: Asthma and chronic obstructive pulmonary disease (COPD) cause a considerable burden of morbidity and mortality in low-income and middle-income countries (LMICs). Access to safe, effective, quality-assured, and affordable essential medicines is variable. We aimed to ... more

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Combined Use of Delamanid and Bedaquiline to Treat Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis: A Systematic Review

G. B. Migliori, E. Pontali, G. Sotgiu, et al. International Journal of Molecular Scienes (2017) C2

Int. J. Mol. Sci. 2017, 18, 341, 1 - 10

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Task-sharing interventions for improving control of diabetes in low-income and middle-income countries: a systematic review and meta-analysis

Linju Maria, J.; et al. (2020) CC

Lancet Glob Health 2020Published OnlineNovember 27, 2020 https://doi.org/10.1016/S2214-109X(20)30449-6

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Infrastructure, policy and regulatory interventions to increase physical activity to prevent cardiovascular diseases and diabetes: a systematic review

Durão, S.; Burns, J.; Schmidt, B. et al. BMC Public Health (2023) CC

Background Noncommunicable diseases are major contributors to morbidity and mortality worldwide. Modifying the risk factors for these conditions, such as physical inactivity, is thus essential. Addressing the context or circumstances in which physical activity occurs may promote physical activity a ... t a population level. We assessed the effects of infrastructure, policy or regulatory interventions for increasing physical activity. Methods We searched PubMed, Embase and clinicaltrials.gov to identify randomised controlled trials (RCTs), controlled before-after (CBAs) studies, and interrupted time series (ITS) studies assessing population-level infrastructure or policy and regulatory interventions to increase physical activity. We were interested in the effects of these interventions on physical activity, body weight and related measures, blood pressure, and CVD and type 2 diabetes morbidity and mortality, and on other secondary outcomes. Screening and data extraction was done in duplicate, with risk of bias was using an adapted Cochrane risk of bias tool. Due to high levels of heterogeneity, we synthesised the evidence based on effect direction. Results We included 33 studies, mostly conducted in high-income countries. Of these, 13 assessed infrastructure changes to green or other spaces to promote physical activity and 18 infrastructure changes to promote active transport. The effects of identified interventions on physical activity, body weight and blood pressure varied across studies (very low certainty evidence); thus, we remain very uncertain about the effects of these interventions. Two studies assessed the effects of policy and regulatory interventions; one provided free access to physical activity facilities and showed that it may have beneficial effects on physical activity (low certainty evidence). The other provided free bus travel for youth, with intervention effects varying across studies (very low certainty evidence). Conclusions Evidence from 33 studies assessing infrastructure, policy and regulatory interventions for increasing physical activity showed varying results. The certainty of the evidence was mostly very low, due to study designs included and inconsistent findings between studies. Despite this drawback, the evidence indicates that providing access to physical activity facilities may be beneficial; however this finding is based on only one study. Implementation of these interventions requires full consideration of contextual factors, especially in low resource settings. more

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Impact of health systems strengthening on coverage of maternal health services in Rwanda, 2000–2010: a systematic review

Maurice Bucagu, Jean M. Kagubare, Paulin Basinga, Fidèle Ngabo, Barbara K Timmons & Angela C Lee Reproductive Health Matters (2012) CC

From 2000 to 2010, Rwanda implemented comprehensive health sector reforms to strengthen the public health system, with the aim of reducing maternal and newborn deaths in line with Millennium Development Goal 5, among many other improvements in national health. Based on a ... more

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Infection Rates and Risk Factors for Infection Among Health Workers During Ebola and Marburg Virus Outbreaks: A Systematic Review

Saranya A, Selvaraj E Lee, Mason Harrell, et al. (2018) CC

The Journal of Infectious Diseases, jiy435, https://doi.org/10.1093/infdis/jiy435. Many outbreaks reported high proportions of infected HWs. Similar HW infection rates and exposure risk factors in both past and recent EVD and MVD outbreaks emphasize the need to improve the implementation of approp ... more

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The impact of mental health and psychosocial support programmes for populations affected by humanitarian emergencies: A systematic review protocol

Bangpan, M; F. Lambert; A. Chiumento; K. Dickson Oxfam (2016) CC

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The economic burden of chronic obstructive pulmonary disease (COPD) in the USA, Europe, and Asia: results from a systematic review of the literature

Rehman, A.; Ahmad Hassali, M.A.; Muhammad, S.A. et al. (2019) CC2

Lack of information about economic burden of COPD is a major cause of lack of attention to this chronic condition from governments and policymakers.

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Global, regional, and national prevalence of, and risk factors for, chronic obstructive pulmonary disease (COPD) in 2019: a systematic review and modelling analysis

Adeloye, D.; Song, P.; Zhu, Y. et al. (2022) CC2

Chronic obstructive pulmonary disease (COPD) is an increasingly important cause of morbidity, disability, and mortality worldwide. We aimed to estimate global, regional, and national COPD prevalence and risk factors to guide policy and population interventions.

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Safety and efficacy of long-acting injectable lenacapavir as pre-exposure prophylaxis to reduce the risk of HIV acquisition: a systematic review
recommended

World Health Organization WHO (2025) C_WHO

Guidelines on lenacapavir for HIV prevention and testing strategies for long-acting injectable pre-exposure prophylaxis. Web Annex B

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Restricting the use of antibiotics in food-producing animals and its associations with antibiotic resistance in food-producing animals and human beings: a systematic review and meta-analysis

K.L Tang, N.P Caffrey, D.B Nóbrega, et al. (2017) CC

Lancet Planet Health 2017 Published Online November 6, 2017 http://dx.doi.org/10.1016/S2542-5196(17)30141-9

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Incidence and Prevalence of Opportunistic and Other Infections and the Impact of Antiretroviral Therapy Among HIV-infected Children in Low- and Middle- income Countries: A Systematic Review and Meta-a

M.-R. B-Lajoie; O. Drouin; G. Bartlett; et al. Clinical Infectious Diseases; Infectious Diseases Society of America (IDSA); hivma; Oxford; WHO (2016) C2

Clinical Infectious Diseases 1586 - 1594 • CID 2016:62 (15 June) • HIV/AIDS

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Ongoing Living Update of COVID-19 Therapeutic Options: Summary of Evidence, Rapid Review 22 February 2022
recommended

Pan American Health Organisation PAHO (2022) C_WHO

This document includes the results of a rapid systematic review of current available literature. The information included in this review reflects t ... more

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A systematic examination of international funding flows for Ebola virus and Zika virus outbreaks 2014-2019: donors, recipients and funding purposes

Quirk, E.J.; A. Gheorghe; K. Hauck BMJ Global Health (2021) C1

There has been no systematic comparison of how the policy response to past infectious disease outbreaks and epidemics was funded. This study aims to collate and analyse funding for the Ebola epidemic and Zika outbreak between 2014 and 2019 in order ... more

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Review Challenges in Chagas Disease Drug Development

Francisco, A.; Jayawardhana, S.; Olmo, F. et al. Molecules MDPI (2020) CC

The protozoan parasite Trypanosoma cruzi causes Chagas disease, an important public health problem throughout Latin America. Current therapeutic options are characterised by limited efficacy, long treatment regimens and frequent toxic side-effects. Advances in this area have been compromised by gaps ... more

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Pharmacological Primary Prevention of Diabetes Mellitus Type II: A Narrative Review

Naveed, A.; Farrukh, L.; Khawar Sana, M.; et al. National Library of Medicine (2020) CC2

The evolving epidemic of type 2 diabetes mellitus has challenged health-care professionals. It stands among the leading causes of mortality in the present world. It warrants new and versatile approaches to improve mortality and the associated huge quality-adjusted life years lost to it once diagnose ... more

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Assessing the Impact of Workforce Nutrition Programmes on Nutrition, Health and Business Outcomes: A Review of the Global Evidence and Future Research Agenda

Dhillon, C.N.; Ortenzi, F. International Journal of Environmental Research and Public Health (2023) CC

One in three people globally suffers from at least one form of malnutrition, leading to poor health outcomes and low productivity in the workplace. The workplace offers an important, relatively unexploited opportunity to address malnutrition in all its forms. This narrative literature ... more

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Patient education in the management of coronary heart disease

Anderson, L.; Brown, J.PR.; Clark, A.M. et al. Cochrane Database of Systematic Reviews (2017) CC

Coronary heart disease (CHD) is the single most common cause of death globally. However, with falling CHD mortality rates, an increasingnumber of people live with CHD and may need support to manage their symptoms and improve prognosis. Cardiac rehabilitation is acomplex multifaceted intervention whi ... more

Safety and efficacy of long-acting injectable lenacapavir as pre-exposure prophylaxis to reduce the risk of HIV acquisition: a systematic review recommended

Ongoing Living Update of COVID-19 Therapeutic Options: Summary of Evidence, Rapid Review 22 February 2022 recommended

Safety and efficacy of long-acting injectable lenacapavir as pre-exposure prophylaxis to reduce the risk of HIV acquisition: a systematic review
recommended

Ongoing Living Update of COVID-19 Therapeutic Options: Summary of Evidence, Rapid Review 22 February 2022
recommended