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Chagas Disease Also called: American trypanosomiasis, South American trypanosomiasis

National Library of Medicine- National Institute of Health (2022) CC

Chagas disease, or American trypanosomiasis, is an illness that can cause serious heart and stomach problems. It is caused by a parasite. Chagas disease is common in Latin America, especially in poor, rural areas. It can also be found in the United States, most often in people who were infected befo... more

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Chagas disease (also known as American trypanosomiasis)

World Health Organization WHO (2022) CC

Chagas disease, also known as American trypanosomiasis, is a potentially life-threatening illness caused by the protozoan parasite Trypanosoma cruzi. About 6–7 million people worldwide are estimated to be infected with T. cruzi. The disease is found mainly in endemic areas of 21 continental Lati... more

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Schistosomiasis Bilharziasis Causes, Symptoms and Treatment

JJ Medicine (2019) CC

Lesson on schistosomiasis (bilharziasis): Causes, Symptoms and Treatment. Schistosomiasis is caused by parasitic blood flukes from the genus schistosoma. Schistosoma cercariae penetrate human skin and enter the bloodstream of the infected individual, where the parasites enter the portal vein. Schist... more

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Schistosomiasis Morbidity Hotspots: Roles of the Human Host, the Parasite and Their Interface in the Development of Severe Morbidity

Mawa, P.; Kincaid-Smith, J.; Tukahebwa, E. et al Frontiers in Immunology (2021) CC

Species of the genus Schistosoma are digenetic trematodes and the causative agents of the Neglected Tropical Disease (NTD) schistosomiasis; a parasitic disease that ranks second only to malaria in terms of socioeconomic impacts. Over 220 million people worldwide are currently infected, 90% of whom l... more

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Progress Toward Global Eradication of Dracunculiasis

Hopkins, D.; Weiss, A.; Roy, S. et al. Morbidity and Mortality Weekly Report MMWR; National Libary of Medicine (2020) CC

Dracunculiasis (Guinea worm disease), caused by the parasite Dracunculus medinensis, is traditionally acquired by drinking water containing copepods (water fleas) infected with D. medinensis larvae, but in recent years also appears increasingly to be transmitted by eating fish or other aquatic anima... more

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Dracunculiasis (guinea-worm disease)

World Health Organization WHO (2022) C_WHO

About a year after infection, a painful blister forms – 90% of the time on the lower leg – and one or more worms emerge accompanied by a burning sensation. To soothe the burning pain, patients often immerse the infected part of the body in water. The worm(s) then releases thousands of larvae (ba... more

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Cystic Echinococcosis (CE)

Global Health; Division of Parasitic Diseases and Malaria (2020) CC

People who accidentally swallow the eggs of the Echinococcus granulosus tapeworm are at risk for infection. Dogs that eat home-slaughtered sheep and other livestock become infected with the tapeworm Echinococcus granulosus and the tapeworm eggs can be found in their stool. Direct contact with infect... more

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Leptospirosis – Fact Sheet - zoonotic disease with epidemic potential

Pan American Health Organization PAHO; World Health Organization WHO (2017) C_WHO

Leptospirosis is a zoonotic disease with epidemic potential, especially after a heavy rainfall, caused by a bacterium called Leptospira. Leptospira interrogans is pathogenic to humans and animals, with more than 200 serologic variants or serovars. Humans usually acquire leptospirosis through dire... more

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A One-Health Approach to Understanding the Epidemiology of Cutaneous Leishmaniasis

Lana J. T. (2021) C2

American cutaneous leishmaniasis (CL) is a severely understudied and neglected“disease of poverty” widespread throughout Peru. Transmission dynamics of CL are complex, requiring sandfly vectors and mammalian reservoir hosts to maintain the pathogen in a local environment whereby incidental hosts... more

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United against Rabies Collaboration

World Health Organization WHO (2019) C_WHO

Rabies is entirely preventable, and vaccines, medicines, tools and technologies have long been available to prevent people from dying of dog-mediated rabies. Nevertheless, rabies still kills about 60 000 people a year, of whom over 40% are children under 15, mainly in rural areas of economically dis... more

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Elimination of human rabies in Goa, India through an integrated One Health approach

Gibson, A.; Yale, G.; Corfmat, J.; et al. nature communications (2022) CC

Rabies is a devastating and societally important zoonotic disease, which is transmitted principally to humans through the bite of infected dogs. This acute, progressive viral encephalitis has the highest case fatality of any infectious disease and kills tens of thousands of people annually, with chi... more

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Rabies Frequently Asked Questions

National Institute for Communicable Disease NICD (2021) CC

Rabies is a zoonotic, vaccine-preventable viral disease that causes damage to the brain and spinal cord in infected animals and humans. A zoonotic disease is a disease that can be transmitted between animals and humans. Rabies is nearly 100% fatal once symptoms appear.

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Rabies MSF medical guidlines

MSF medical guidelines (2018) CC

Rabies is a viral infection of wild and domestic mammals, transmitted to humans by the saliva of infected animals through bites, scratches or licks on broken skin or mucous membranes. In endemic areas (Africa and Asia), 99% of cases are due to dog bites and 40% of cases are children under 15 years... more

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Community-Based Interventions for the Prevention and Control of Cutaneous Leishmaniasis

Polidano, K.; Wenning, B.; Ruiz-Cadavid. et al Multidisciplinary Digital Publishing Institute MDPI (2022) CC

Cutaneous leishmaniasis (CL) is a parasitic disease caused by infection with a vector-borne protozoan parasite of the genus Leishmania spp. The parasite is transmitted by the bite of an infected phlebotomine sand fly. Infection results in skin lesions which take a long time to heal and may leave per... more

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Leishmania

National Organization for Rare Disorders NORD (2019) CC

Leishmaniasis is an infectious disease caused by protozoan parasites of the genus, Leishmania. Protozoa are microscopic, single-celled organisms. The parasites that cause the disease are transmitted to people through the bites of certain species of infected sand flies.

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Global distribution maps of the leishmaniases

Pigott, D.; Bhatt, S.; Golding, N.; et al. eLife Sciences Publications Ltd. (2014) CC

Each year 1–2 million people are diagnosed with a tropical disease called leishmaniasis, which is caused by single-celled parasites. People are infected when they are bitten by sandflies carrying the parasite, and often develop skin lesions around the bite site. Though mild cases may recover on th... more

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Geographical Distribution of Cutaneous Leishmaniasis and Pathogenesis

Flaih, M. (2021) CC

Leishmaniasis is still considered to be a global health problem, which spreads in most countries in the world. Leishmania is an intracellular obligate protistan parasite that causes different clinical symptoms in infected humans and other animals. There are clinically different types of the disease ... more

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What is Leishmaniasis? An introduction and overview

Appuhamy, R.; Clark, J. (2015) CC

Leishmaniasis is a disease caused by a group of protozoan parasites called Leishmania. It is classified as a Neglected Tropical Disease and affects some of the poorest countries in the world causing 20-30,000 deaths each year. The disease is transmitted through the bite of an infected sandfly and ca... more

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Global elimination of dog-mediated human rabies. Report

World Health Organization (WHO) (2016) C_WHO

Rabies remains an under-reported neglected zoonosis with a case-fatality rate of almost 100% in humans and animals. Dog-mediated human rabies causes tens of thousands of human deaths annually despite being 100% preventable. More than 95% of human cases are caused by the bite of a rabies-infected dog... more

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Global elimination of dog-mediated human rabies. Poster

World Health Organization (WHO) (2016) C_WHO