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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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ASEAN Disaster Management Reference Handbooks

Center for Excellence in Disaster Management and Humanitarian Assistance (2022) C1

Disaster Management Reference Handbook Series Overview. Floods, storms, and wind account for large proportions of displacement compared to other disasters. Floods are the most frequent type of disaster whereas wind-related disasters constitute the biggest losses in terms of economic damage, displac... more

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Human Development Report 2020. The Next Frontier: Human Development and the Anthropocene

UN Development Programme UNDP (2020) CC

Overview. The COVID-19 pandemic is the latest crisis facing the world, but unless humans release their grip on nature, it won’t be the last, according to a new report by the United Nations Development Programme (UNDP), which includes a new experimental index on human progress that takes into acco... more

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Training Guide: Mental Health and Psychosocial Support in Emergencies

International Federation of Red Cross and Red Crescent Societies IFRC (2024) CC

This MHPSS in Emergencies training aims to prepare MHPSS responders, disaster managers, and emergency team leaders for work in the field by building understanding of basic concepts of MHPSS in emergencies as well as planning and implementing PSS activities. It is for MHPSS focal points from the Red ... more

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WHO good manufacturing practices for pharmaceutical products: main principles

World Health Organization WHO (2014) C_WHO

Licensed pharmaceutical products (marketing authorization) should be manufactured only by licensed manufacturers (holders of a manufacturing authorization) whose activities are regularly inspected by competent national authorities. This guide to GMP shall be used as a standard to justify GMP status,... more

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Cities leading the way: Seven climate action plans to deliver on the Paris Agreement

C40 Cities (2019) CC

Cities can help nations achieve their Paris Agreement commitment by supporting the implementation of transformational actions to increase the supply of renewable energy, improve building energy efficiency, increase access to affordable, low carbon transport options, and change consumption patterns. ... more

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Assessing Health Vulnerabilities and Adaptation to Climate Change

Berry, P.; P. M. Enright, J. Shumake-Guillemot et al. (2018) CC

Int. J. Environ. Res. Public Health 2018, 15(12), 2626; https://doi.org/10.3390/ijerph15122626 Climate change is increasing risks to human health and to the health systems that seek to protect the safety and well-being of populations. Health authorities require information about current associatio... more

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Northeast Nigeria Health Sector - Humanitarian Response Strategy 2025 - 2027 (December 2024)

Government of Nigeria; Health Cluster; World Health Organization WHO (2024) CC

The protracted humanitarian situation in northeastern Nigeria, particularly in Borno, Adamawa, and Yobe (BAY) States, remains a concern due to ongoing insecurity, displacement, food insecurity, disease outbreaks, and climate-related shocks. To address these complex challenges, the health sector has ...developed a comprehensive humanitarian response strategy aligned with the three States Development plans, Durable Solutions for the Population Displacement Plan, and the Humanitarian Need Response Plan for 2025. This strategy aims to reduce morbidity and mortality among crisisaffected populations by ensuring timely, equitable, and effective delivery of lifesaving health services, while strengthen the resilience of health system and enhancing local and national capacities for sustainable health response in protracted emergency. Supported by an in-depth analysis of the ongoing health humanitarian response using the Strengths, Weaknesses, Opportunities, and Threats (SWOT) methodology, the strategy is guided by three key objectives: 1. Provide access to lifesaving interventions and sustain an effective response to the prolonged health emergency. 2. Prevent, mitigate, and prepare for health risks from all hazards and respond to all health emergencies. 3. Advance the primary health care approach and essential health system capacities for universal health coverage. To achieve these objectives, the strategy employs the “Five C” framework which refers to: • Collaborative Surveillance: Enhancing collaborative efforts for effective monitoring. • Community Protection: Implementing community-based protection measures. • Safe and Scalable Care: Ensuring care that is both secure and scalable. • Access to Countermeasures: Facilitating access to necessary countermeasures. • Emergency Coordination: Coordinating emergency responses efficiently. These proactive approaches are designed to be more anticipatory and preemptive rather than reactive, aiming to meet the needs of the crisis-affected population by providing lifesaving interventions, enhancing preventive and anticipatory actions, and ensuring the resilience of the health system. All actions are guided by International Humanitarian Standards and the Humanitarian Principles. The implementation of the health humanitarian response strategy will involve collaboration with local authorities, non-governmental organizations (NGOs), and international organizations. The strategy emphasizes localization and resource mobilization, efficient logistics and supply chain management, mainstreaming protection, and the deployment and training of healthcare workers. Continuous monitoring and periodic evaluation will ensure the effectiveness of the response. Cross-sector collaboration with sectors such as WASH, Nutrition, Education, and Protection will be crucial to enhance the quality and reach of health interventions. Additionally, sustainability and transition approaches will ensure long-term health outcomes and benefits, bridging the gap from humanitarian to development efforts. By adopting this comprehensive approach, the humanitarian response in northeastern Nigeria, particularly in BAY States, can be effectively guided, ultimately reducing the suffering of affected populations. more

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Protecting health through urban redevelopment of contaminated sites: planning brief

World Health Organization WHO, Regional Office of Europe (2021) C_WHO

This brief summarizes the lessons learned across Europe on the redevelopment of contaminated sites as a part of urban planning and renewal. Specifically, it aims to provide information on the health and environmental impacts to be considered during site redevelopment projects, and to identify good p... more

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Schutz der Gesundheit durch städtebauliche Neuentwicklung kontaminierter Standorte

World Health Organization WHO, Regional Office of Europe (2021) C_WHO

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Global Health Security (GHS) Index

Nuclear Threat Initiative (NTI) and the Johns Hopkins Center for Health Security (JHU) The Economist Intelligence Unit (EIU) (2019) CC

The GHS Index is intended to be a key resource in the face of increasing risks of high-consequence and globally catastrophic biological events and in light of major gaps in international financing for preparedness. These risks are magnified by a rapidly changing and interconnected world; increasing ... more

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Myanmar Community Based Disaster Risk Management

[Asian Disaster Preparedness Center (ADPC)] (2009) C1

This Manual is primarily intended for community level volunteers trained in Community Based Disaster Risk Management (CBDRM) and CBDRM Practitioners and Professionals.
The year of publication is not specified in the document.

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Generic procedures for medical response during a nuclear or radiological emergency

World Health Organization WHO; International Atomic Energy Agency IAEA (2005) C_WHO

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WHO technical guidance notes on Sendai Framework reporting for Ministries of Health

World Health Organization WHO (2020) CC

The Guidance Notes seek to help operationalize, simplify and standardize the collection and reporting of data through the application of common language and methods. They provide information on the key issues to take into account in the collection of health data and the types of data that should be ... more

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HCT Myanmar – Inter-agency Emergency Response Preparedness (ERP) Plan (June 2017)

Humanitarian Country Team (HCT), Myanmar (2017) C1

The ERP approach seeks to improve effectiveness by reducing both time and effort, enhancing predictability through establishing predefined roles, responsibilities and coordination mechanisms. The Emergency Response Preparedness Plan (ERPP) has four main components: i) Risk Assessment, ii) Minimum Pr... more

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A framework for mental health and psychosocial support in radiological and nuclear emergencies

World Health Organization (WHO) and InterAgency Standing Committee (IASC) (2020) C_WHO

The health impact of radiological and nuclear emergencies can last for decades. Lessons learned from past radiological and nuclear accidents have demonstrated that the mental health and psychosocial consequences can outweigh the direct physical health impacts of radiation exposure. International rad... more

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Zika, Dengue and Chikungunya Toolkit: Adaptation for Latin America and the Caribbean. School/Youth module

International Federation of Red Cross And Red Crescent Societies (2017) C1

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DRC: Plan de gestion des déchets biomedicaux

Ministère de la Santé Publique, Republique Démocratique du Congo (2016) C1

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Waste Category and Colour-Coding Table

Ministry of Health. Environmental Health Department and Swaziland Health Laboratory Services (SHLS). The Goverment of the Kingdom of Swaziland (2015) C1

Accessed 3rd of October 2015

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Quick Guide to Disposing Laboratory Waste

Ministry of Health. Environmental Health Department and Swaziland Health Laboratory Services (SHLS). The Goverment of the Kingdom of Swaziland (2015) C1

Accessed 3rd of October 2015