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Laboratory testing for Zika virus and dengue virus infections: interim guidance
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World Health Organization (2022) C_WHO
Zika and dengue viruses remain significant public health threats. These viruses share the same Aedes (Stegomyia) mosquito vectors and geographic distributions but infections cannot be readily distinguished clinically and need to be differentiated from each other, and from other circulating arboviral... more
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Organización Mundial de la Salud OMS OPAS (2021) C_WHO
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Especificacoes tecnicas para selecao de testes diagnosticos in vitro essenciais para SARS-COV-2, 14 de junho de 2021

Organização Mundial da Saúde (OMS) OPAS (2021) C_WHO
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The ‘jigsaw puzzle’ approach to building a diagnostic picture of asthma in primary care over time

Ryan, D.; Kocks, J.; Correia de Sousa, J. et al. International Primary Care Respiratory Group (2023) CC
Since there is no single objective diagnostic test for asthma this study suggests an approach of collecting and assembling pieces of clinical information to create a diagnostic picture, like making a jigsaw puzzle. These pieces should include demonstration of symptom and airway variability and/or br... more
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FIND COVID-19 Diagnostics Resource Centre
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FIND (2020) CC
FIND is collating an overview of SARS-CoV-2 tests that are commercially available or in development for the diagnosis of COVID-19. We do not guarantee that this is a comprehensive list, since the information below has been submitted voluntarily by test suppliers and is not independently verified. Pl... more
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Rapid diagnostics for tuberculosis detection

Open WHO; World Health Organization WHO (2021) C_WHO
This course will provide you with the knowledge and skills needed to implement WHO-recommended TB tests and algorithms. It includes the latest recommendations for novel tests for TB diagnosis and detection of drug resistance, as well as the most recent WHO policy guidance for the use of those tests.... more
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Second WHO Model List of Essential In Vitro Diagnostics

World Health Organization WHO (2019) C_WHO
The updated List of Essential Diagnostics contains 46 general tests that can be used for routine patient care as well as for the detection and diagnosis of a wide array of disease conditions, and 69 tests intended for the detection, diagnosis and monitoring of specific diseases. The List is divid... more
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Diagnostic Techniques for Soil-Transmitted Helminths – Recent Advances

Khurana S., Singh S. et al. Dovepress (2021) C2
Diagnostic performance, cost-effectiveness, ease of performance, rapidity and in-field applicability of tests for Soil-transmitted helminth infections.
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Laboratory testing for severe acute hepatitis of unknown aetiology in children: interim guidance, 17 June 2022

World Health Organization WHO (2022) C_WHO
This document provides interim guidance to countries on testing considerations and strategies for suspect cases of severe acute hepatitis of unknown aetiology in children. It is primarily intended for clinical, programmatic, laboratory and diagnostic stakeholders across Member States and national pu... more
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Diagnostic target product profiles for monitoring, evaluation and surveillance of schistosomiasis control programmes

World Health Organization WHO (2021) C_WHO
Health ministries currently lack effective tools for monitoring and evaluation of schistosomiasis control programmes. Egg detection can be used, but the cost, challenges of obtaining samples, and the need for trained personnel and equipment limit the frequency of monitoring. The purpose of this TPP ... more
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WHO operational handbook on tuberculosis: Module 3: Diagnosis - Rapid diagnostics for tuberculosis detection 2021 update
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World Health Organization WHO (2021) C_WHO
6 July 2021. Three new nucleic acid amplification test (NAAT) classes are endorsed by WHO and included. The latest operational handbook includes the new classes recommended by WHO. It aims at facilitating the implementation of the WHO recommendations by the Member States, technical partners, and ot... more
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Recommandations pour les stratégies de dépistage et les capacités de diagnostic du SARS-CoV-2 à l’échelle nationale
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World Health Organization WHO (2021) C_WHO
orientations provisoires, 25 juin 2021. Des tests de diagnostic rapides et précis sont un outil essentiel pour prévenir et contrôler la propagation du COVID-19. Ce document décrit les recommandations relatives aux stratégies nationales de dépistage et à l'utilisation de la PCR et des tests an... more
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Laboratory testing for diphtheria in outbreak settings: Interim guidance, 26 January 2024

World Health Organization WHO (2024) C_WHO
This document provides detailed guidance on laboratory testing for suspected diphtheria cases during significant outbreaks or in low-resource settings. It aims to supplement and build on other existing WHO guidance documents on surveillance standards, diagnostics and research on Corynebacterium by p... more
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Interim guidance for healthcare providers and Zika virus laboratory diagnosis
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European Centre for Disease Prevention and Control (2016) C1
This document aims to present an algorithm for deciding whom to test and provide guidance on the laboratory tests for Zika virus infection diagnosis in order to support clinical diagnostic and case reporting through surveillance among EU Member States. The algorithm is not intended for clinical man... more
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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC
Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde... more
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Diagnostics, therapeutics, vaccine readiness, and other health products for COVID-19
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World Health Organization WHO (2021) C_WHO
Interim Guidance, 12 July 2021; This tool was developed to assess present and surge capacities for the treatment of COVID-19 in health facilities. It allows health facilities to assess the availability and status of stockout of critical COVID-19 medicines, equipment and supplies on site and to ident... more
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Laboratory diagnosis of Buruli ulcer
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Portaels, F- World Health Organization WHO (2014) C_WHO
A manual for health care providers. This manual provides expert guidance on the laboratory techniques and procedures used in the diagnosis of Buruli ulcer, a disease caused by Mycobacterium ulcerans. Aimed at laboratory technicians and scientists working on this disease, the manual details the exac... more
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Diagnostic methods for the control of strongyloidiasis, Virtual meeting, 29 September 2020

World Health Organization WHO (2021) C_WHO
23 March 2021 The meeting addressed the last key area, that is, determining the best method or combination of diagnostic methods for a control programme for S. stercoralis infections in humans. Dr Montresor’s presentation highlighted that while there is currently no “gold standard” for the... more
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Diagnostics to support the eradication of yaws—Development of two target product profiles

Fongwen, N.; Handley, B.; Martin, D. et al. PLoS Neglected Tropical diseases (2022) CC
Yaws is targeted for eradication by 2030, using a strategy based on mass drug administration (MDA) with azithromycin. New diagnostics are needed to aid eradication. Serology is currently the mainstay for yaws diagnosis; however, inaccuracies associated with current serological tests makes it difficu... more
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Fever Diagnostic Technology Landscape
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UNITAID World Health Organisation (WHO) (2018) C_WHO
1st edition. Unitaid’s report describes a slate of new devices that can more efficiently identify dangerously ill children so that they can be treated immediately. These tools make it easier to recognize danger signs, and support integrated approaches to reducing childhood deaths from the three ... more