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Publication Years
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1
Appropriate use and withdrawal of inhaled corticosteroids (ICS) in patients with chronic obstructive pulmonary disease (COPD)
Román-Rodríguez, M.; Tsiligianni, I.; Wiliams, S.; et al.
International Primary Care - Respiratory Group
(2020)
CC2
The document "Appropriate use and withdrawal of inhaled corticosteroids (ICS) in patients with chronic obstructive pulmonary disease (COPD)" from the IPCRG provides guidance on when to start, adjust, or discontinue ICS in COPD treatment. It highlights the benefits and risks, emphasizing personalized
...
treatment based on patient history, exacerbation frequency, and eosinophil count, while detailing how to optimize bronchodilator use to manage symptoms effectively.
more
Introducing the IPCRG
International Primary Care - Respiratory Group
International Primary Care - Respiratory Group
(2024)
CC2
The International Primary Care Respiratory Group (IPCRG) is a clinically-led charitable company that works locally in primary care and collaborates globally to improve respiratory health. Our vision
...
is that, through universal access to the right care, everyone can breathe and feel well.
more
Under-diagnosis of asthma in ‘under-fives’ may be alleviated by improved inquiry into disease history. We assessed a questionnaire-based screening tool for asthma among 614 ‘under-fives’ with severe respiratory illness in Uganda. The questio
...
nnaire responses were compared to post hoc consensus diagnoses by three pediatricians who were guided by study definitions that were based on medical history, physical examination findings, laboratory and radiological tests, and response to bronchodilators. Children with asthma or bronchiolitis were categorized as “asthma syndrome”. Using this approach, 253 (41.2%) had asthma syndrome. History of and present breathing difficulties and present cough and wheezing was the best performing combination of four questionnaire items [sensitivity 80.8% (95% CI 77.6–84.0); specificity 84.7% (95% CI 81.8–87.6)]. The screening tool for asthma syndrome in ‘under-fives’ may provide a simple, cheap and quick method of identifying children with possible asthma. The validity and reliability of this tool in primary care settings should be tested.
more
Background
Asthma remains highly prevalent, with more severe symptoms in low-income to middle-income countries (LMICs) compared with high-income countries. Identifying risk factors for severe asthma symptoms can assist with improving outcomes. We aimed to determine the prevalence, severity and ris
...
k factors for asthma in adolescents in an LMIC.
Methods
A cross-sectional survey using the Global Asthma Network written and video questionnaires was conducted in adolescents aged 13 and 14 from randomly selected schools in Durban, South Africa, between May 2019 and June 2021.
Results
A total of 3957 adolescents (51.9% female) were included. The prevalence of lifetime, current and severe asthma was 24.6%, 13.7% and 9.1%, respectively. Of those with current and severe asthma symptoms; 38.9% (n=211/543) and 40.7% (n=147/361) had doctor-diagnosed asthma; of these, 72.0% (n=152/211) and 70.7% (n=104/147), respectively, reported using inhaled medication in the last 12 months. Short-acting beta agonists (80.4%) were more commonly used than inhaled corticosteroids (13.7%). Severe asthma was associated with: fee-paying school quintile (adjusted OR (CI)): 1.78 (1.27 to 2.48), overweight (1.60 (1.15 to 2.22)), exposure to traffic pollution (1.42 (1.11 to 1.82)), tobacco smoking (2.06 (1.15 to 3.68)), rhinoconjunctivitis (3.62 (2.80 to 4.67)) and eczema (2.24 (1.59 to 3.14)), all p<0.01.
Conclusion
Asthma prevalence in this population (13.7%) is higher than the global average (10.4%). Although common, severe asthma symptoms are underdiagnosed and associated with atopy, environmental and lifestyle factors. Equitable access to affordable essential controller inhaled medicines addressing the disproportionate burden of asthma is needed in this setting.
more
Demographic and epidemiological transitions are changing the age structure of the population and the most common diseases. Non-communicable respiratory diseases are an increasing problem at both ends of the age range in low-income and middle-income
...
countries. In children, who represent a large proportion of the total population, the increasing problem of asthma is a strain on health services. Improved survival of the older population is increasing the proportion of morbidity and mortality attributable to chronic lung diseases. Health services in low-resource countries are poorly adapted to treating chronic diseases. Designed to respond episodically to acute disease, almost all historical investment has focused on infectious diseases. Crucial to the successful management of chronic diseases is an infrastructure designed to support pro-active management, providing not only an accurate diagnosis, but also a secure supply of cost effective drugs at an affordable price. The absence of such an infrastructure in many countries and the market failure that makes drugs generally more expensive in low-resource regions means that many people with chronic non-communicable lung diseases are not given effective treatment. This has damaging economic consequences. The common causes of poor lung health in lowincome countries are not the same as those in richer countries, and there is a need to study why they are so common and how best to manage them.
more
This guide provides a systematic, practical approach to support primary care and other healthcare professionals to improve the care of peopel over the age of 18 years with difficult to manage asthma.
Adults and adolescents 12+ years. Asthma medication options: Adjust treatment up and down for individual patient needs
The ‘jigsaw puzzle’ approach to building a diagnostic picture of asthma in primary care over time
Ryan, D.; Kocks, J.; Correia de Sousa, J. et al.
International Primary Care Respiratory Group
(2023)
CC
Since there is no single objective diagnostic test for asthma this study suggests an approach of collecting and assembling pieces of clinical information to create a diagnostic picture, like making a jigsaw puzzle. These pieces should include demonstration of symptom and airway variability and/or br
...
onchodilator responsiveness over time, to support a clinical diagnosis.
more
Туберкулез (ТБ)
European Lung Foundation, European Respiratory Society
European Lung Foundation, European Respiratory Society
(2013)
C1
Факты о туберкулезе
This policy brief explores the impact of air pollution on health and address the air quality issue in the response to noncommunicable diseases (NCDs). It also provides key actions that policy makers, NGOs and health professionals can take to ensure that every one can breathe clean air.
Asbestos-related diseases in mineworkers: a clinicopathological study
Ndlovu, N.; Rees, D.; Murray, J.; et al.
ERJ Open Research, part of the European Respiratory Society (ERS)
(2017)
CC
This study compared clinical and autopsy findings for three asbestos-related diseases (asbestosis, mesothelioma and lung cancer) in former asbestos mineworkers, and explored factors that influenced agreement between clinical and autopsy findings using data from two compensation systems. In South Afr
...
ica, statutory compensation for occupational lung diseases in mineworkers makes provisions for autopsy examinations of the cardio-respiratory organs at the National Institute for Occupational Health (NIOH) in Johannesburg. In addition, the Johannesburg-based Asbestos Relief Trust and Kgalagadi Relief Trust (the “Trusts”) compensate individuals with defined asbestos-related diseases who worked in or lived near qualifying asbestos mining or processing operations. The Trusts also compensate dependents of deceased qualifying mineworkers and therefore encourage statutory autopsies for the detection of previously undiagnosed asbestos-related disease or disease that may have progressed to higher compensation grades.
more
Under- and over-diagnosis of COPD: a global perspective
Ho T., Cusack R.P., Chaudhary N. et al.
Breathe, part of the European Respiratory Society (ERS)
(2019)
CC2
The article "Under- and over-diagnosis of COPD: a global perspective" reviews the worldwide variation in the prevalence of chronic obstructive pulmonary disease (COPD) and issues related to its misdiagnosis. It highlights that COPD is under-diagnosed due to factors such as limited access to spiromet
...
ry and variable diagnostic criteria, especially in low- and middle-income countries. Conversely, over-diagnosis often results from reliance on non-standard criteria or inadequate spirometry use. The article discusses key risk factors, including age, gender, exposure to pollutants, and comorbidities, and emphasizes the need for standardized diagnostic practices to better address and manage COPD globally.
more
Chronic respiratory diseases, such as asthma and
chronic obstructive pulmonary disease, kill more than
four million people every year and affect hundreds
of millions more. These diseases erode the health
and well-being of the patients and have a
...
negative
impact on families and societies. Women and
children are particularly vulnerable, especially those
in low and middle income countries, where they are
exposed on a daily basis to indoor air pollution from
solid fuels for cooking and heating. In high income
countries, tobacco is the most important risk factor
for chronic respiratory diseases, and in some of
these countries, tobacco use among women and
young people is still increasing.
more
Chronic respiratory diseases (CRDs) are among the leading causes of death worldwide, with asthma rated the most common chronic disease affecting children (1). Globally, about 300 million people have asthma, and current trends suggest that an additio
...
nal 100 million people may be living with asthma by 2025.
more
Human Respiratory Syncytial Virus is a negatively stranded, enveloped RNA virus and belongs to the Orthopneumovirus genus of the Pneumoviridae family. It is divided into two antigenic groups (subgroups) hRSV A and hRSV B] The genome is 15 kb long
...
with 10 gene transcripts encoding 11 proteins of which the G glycoprotein and the fusion (F) glycoprotein are major surface proteins that function in attachment. Antigenic groups can be further divided into 16 RSV-A and 22 RSV-B genotypes based on the sequence variability of the second hypervariable region (HVR2) of the distal third region of the G gene.
more
Journal of Pulmonary & Respiratory Medicine 6: 326. doi:10.4172/2161-105X.1000326
Does the patient meet the case definition for a COVID-19 case?
Nation Institute for Communicable Diseases - Division of the National Health Laboratory Service
Department: Health Republic of South Africa
(2020)
C2
Persons with acute respiratory illness with sudden onset of at least one of the following: cough, sore throat, shortness of breath or fever [≥ 38°C (measured) or history of fever (subjective)] irrespective of admission status AND In the 14 days p
...
rior to onset of symptoms, met at least one of the following epidemiological criteria: Were in close contact1 with a confirmed2 or probable3 case of SARS-CoV-2 infection; OR Had a history of travel to areas with presumed ongoing community transmission of SARS-CoV-2; (Visit WWW.NICD.AC.ZA for an updated case definition). OR Worked in, or attended a health care facility where patients with SARS-CoV-2 infections were being treated. OR Admitted with severe pneumonia of unknown aetiology.
more
Preliminary Stakeholder Engagement Plan (SEP)
India COVID-19 Emergency Response and Health Systems Preparedness Project (P173836)
Ministery of Health and Familiy Welfare - Government of India
(2020)
C2
A new respiratory infectious disease, COVID-19, caused by a new coronavirus called SARS-CoV-2, emerged in early December 2019. Since then, the virus has spread to India and 106 other countries in Asia, Europe, North America, Africa, and Oceania. On
...
March 11, the World Health Organization (WHO) declared the outbreak a pandemic, which has since rapidly evolved. As an economic hub with substantial global connectivity and movement of people and goods, India is directly impacted by the COVID-19 pandemic. Although it is too early to gauge the full spectrum of the outbreak’s social and economic impacts, COVID-19 has already caused lockdowns in China, Korea, and in many countries in Europe, and in some states of India, suspension of schools and universities, disruption of food systems and other supply chains, as well as a slowdown in trade between India and rest of the world.
more
Данный курс предназначен для практикующих врачей, работающих в отделениях реанимации и интенсивной терапии (ОРИТ) в странах с низким и средним уровнем дохода, а та
...
же занимающихся клиническим ведением взрослых больных и детей с тяжелыми формами острой респираторной инфекции (ТОРИ), включая тяжелую пневмонию, острый респираторный дистресс-синдром (ОРДС), сепсис и септический шок. Данное практическое руководство может быть использовано в работе специалистов в области здравоохранения, участвующих в организации интенсивной терапии во время вспышек сезонного гриппа, вызванного вирусом птичьего гриппа (H5N1, H7N9), коронавирусом MERS-CoV и новым коронавирусом COVID-19, или во время других новых эпидемий респираторной вирусной инфекции.
WHO Clinical Care Severe Acute Respiratory Infection Training
also available in : English - français - Português - Bahasa Indonesia - Tiếng Việt - Español - македонски - العربية - Tetun
more
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV‑2) causing coronavirus disease 2019 (COVID-19) has reached pandemic levels;
Patients with cardiovascular (CV) risk factors and established cardiovascular disease (CVD) represent a vulnerab
...
le population when suffering from COVID-19;
Patients with cardiac injury in the context of COVID-19 have an increased risk of morbidity and mortality
more
